Protein

Protein accession
A0A8S5PWF5 [UniProt]
Representative
5LPSD
Source
UniProt (cluster: phalp2_8060)
Protein name
Cell wall hydrolase autolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MHKRRQRRRGHGHALSAVAACGHLLRGGARVRVCISVGHGKSAGGGYDSGAVGGGFHEFRIARKIGFYIAEALKKYGCDAVLINYDADMYLTDRIAYVNRENFDLAAEIHLNAGGGTGSEVYYKHADEDGKKLAAKISAGIAKTFSLRDRGAKTKLNSAGGDYFGFVRSVGCRSLLIETVFIDSSSDRKNVETEAGQKKCGESIAASIAEFYRLCVKNKPQKVAQYADIRAGDRVKIIGKNYATGQRIPSWVKLRTHTVAKVEPSRALLKEINSWVRLSDLRLAARPSVSVGSVVFIKPGAVYGGCTSARGKRVPDSQLSPKKHTVTKVQQNRGTLEALLGDISSWVAVGSLEEV
Physico‐chemical
properties
protein length:355 AA
molecular weight:38384,4 Da
isoelectric point:9,84
hydropathy:-0,28
Representative Protein Details
Accession
5LPSD
Protein name
5LPSD
Sequence length
304 AA
Molecular weight
33267,83120 Da
Isoelectric point
9,61612
Sequence
MKISVCIGHGKSQSGKYDSGAVAAGYQEFKLARAIGKCLKQELSKYNCTVDLINYDGDKNLSERIKYVNSKGYDLNMELHLNAGGGTGPEVYYRHTSKQGKALAAAISKSISTNLGLKNRGAKTKLVNGQDYFGCVREIKCMSFLVENVFIDTKGDRDKVIYASGQEQCAKAIATAVAKYYGLKLKGSPAPAPAPSPKPAPTPSSKKSNTEIAKEVIQGKWGNGAERKKRLEDAGYDYAAVQKEVEKLLYEPEKKPVKKSVDEVAREVIAGKWGNGAKRMYNLTKAGYNYYAVQKRVNKLLKGK
Other Proteins in cluster: phalp2_8060
Total (incl. this protein): 13 Avg length: 305,4 Avg pI: 9,61
Protein ID Length (AA) pI
5LPSD 304 9,61612
5OLg8 300 9,56287
5SCq7 295 9,53624
5Uif5 300 9,57222
5X5Ef 303 9,64829
5Yax2 303 9,58795
62UTj 300 9,60748
6iF9V 301 9,56248
6sMWN 303 9,58795
7WP4K 303 9,54417
8b1b2 303 9,62489
8toUP 300 9,62515
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_38795
1mhnb
 2 45,4% 240 4.475E-54
2 phalp2_25310
8uXcI
 3 42,1% 192 2.881E-43
3 phalp2_3787
5STbs
 32 32,6% 346 1.129E-34
4 phalp2_36558
1J8Qa
 2 34,4% 293 2.451E-33
5 phalp2_6489
uh4U
 19 35,8% 293 1.137E-30
6 phalp2_4252
7Y66x
 61 33,5% 301 2.064E-28
7 phalp2_11834
8nufL
 33 35,9% 203 7.675E-25
8 phalp2_17577
6kJnH
 104 34,3% 189 5.422E-20
9 phalp2_23918
1NTlO
 42 34,8% 250 1.176E-17
10 phalp2_6374
7yZe6
 41 34,4% 203 2.132E-17

Domains

Domains [InterPro]
Ami3
CW_7
CW_7
Representative sequence (used for alignment): 5LPSD (304 AA)
Member sequence: A0A8S5PWF5 (355 AA)
1 304 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF08230

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctaMv1
[NCBI] 		2825131 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015528 [NCBI]
CDS location
range 2503 -> 3570
strand -
CDS
ATGCACAAGAGACGACAGCGGCGGCGAGGGCACGGTCATGCACTATCTGCCGTCGCAGCTTGTGGGCATTTACTTCGAGGAGGTGCGAGAGTGAGAGTTTGTATATCCGTGGGTCACGGAAAATCGGCGGGCGGCGGCTATGACAGCGGCGCGGTCGGAGGGGGCTTCCACGAGTTTCGCATAGCGCGAAAGATAGGCTTTTATATCGCCGAGGCGCTCAAAAAATACGGCTGCGATGCCGTGCTCATAAACTACGATGCCGATATGTATCTGACGGACAGGATAGCTTATGTCAACCGCGAGAACTTCGATCTGGCTGCCGAGATTCATCTGAATGCAGGCGGCGGAACGGGGAGCGAGGTCTATTATAAACACGCCGACGAGGACGGCAAAAAGCTCGCCGCGAAGATAAGCGCGGGCATTGCGAAAACATTTTCACTGCGCGACAGGGGAGCTAAAACGAAGCTCAATTCCGCAGGCGGCGATTATTTCGGTTTCGTCCGCTCGGTCGGGTGCCGCAGTCTGCTCATCGAGACCGTGTTCATAGACAGCTCTTCGGACAGAAAGAATGTCGAAACGGAAGCGGGACAGAAAAAGTGCGGCGAATCGATTGCCGCGTCGATAGCCGAATTTTACAGGCTTTGCGTAAAAAACAAACCGCAAAAAGTCGCGCAGTATGCCGATATCAGAGCGGGCGACCGCGTGAAAATTATAGGCAAAAACTATGCCACGGGTCAGCGAATCCCGTCGTGGGTGAAGCTCAGAACGCATACCGTCGCAAAAGTCGAGCCGAGCCGCGCGCTGCTCAAGGAGATAAACTCTTGGGTCAGGCTCTCTGACTTGAGACTCGCGGCGAGACCGTCCGTCTCGGTCGGGAGCGTTGTTTTTATAAAGCCCGGTGCGGTCTACGGCGGCTGCACCTCGGCGCGCGGAAAGCGCGTGCCCGATTCTCAGCTCTCGCCGAAAAAACACACCGTCACAAAAGTTCAACAGAATCGCGGCACGCTCGAAGCCCTGCTCGGCGATATTTCGAGCTGGGTCGCGGTCGGCAGTCTCGAGGAGGTGTGA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5LPSD) rather than this protein.
PDB ID
5LPSD
Method AlphaFoldv2
Resolution 88.00
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50