Protein

Protein accession
A0A8S5PSJ4 [UniProt]
Representative
5TtYr
Source
UniProt (cluster: phalp2_25915)
Protein name
Peptidoglycan hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MDKELFIQKVAEKVRKYAPLYGIGVHSPIIAQAIIESGWGSSVLASKYNNYFGLKCGSSWKGGSVNMATREEYKPGVVTNIRDNFRTYEDFDAGIRGYFEFIGYSRYSNLKGVTNPREYCEKLKSDGYATSSSYVDTLMRVIQENNLTRFDNSDKPQSDVDIENLAQRVIKGEFGSGEERKALLGGNYEKVQQRVNEILGSSKPKYNIDDLARRAIRGEFGNGLTRKAKLEKMERGLYDKVQKRINEMMK
Physico‐chemical
properties
protein length:250 AA
molecular weight:28428,8 Da
isoelectric point:9,25
hydropathy:-0,70
Representative Protein Details
Accession
5TtYr
Protein name
5TtYr
Sequence length
493 AA
Molecular weight
54733,43290 Da
Isoelectric point
8,86016
Sequence
MEKQEFIKKIAALVKKYAGLYGITVHSPIIGQAILESGWGESKLAAVYHNYFGLKCGTAWKGKSVNMTTKEEYTAGTLTTIKDNFRVYDSMEEGVKGYFEFIQLTRYANLKGITDPKVYLNTIKADGYATSSTYVNNVYALIVQYNLTQYDKNVDNVDNSKKEGTKVGYSRQAVVDLVESWIGKNEADGSYKSIINIYNSFTGKFPRNTKMEYSWAWCACCWSALAVALKYTAIMPIEISCYYLIEEAKKMGVWVENDAYVPKPGDAVLYDWNDTGKGDCTGTPDHVGTVTYTNKEAGYFVVTEGNYNDAVKKRTVSINGRYIRGFIVPKYDTDTAVQNPVRKPGKTVKEVAHEVIAGQWGNGDERVSALRICGYDPVAVQTEVNSILNGSAVTTDKTKQDSNQAITRTVKATCYAKKKNPAIAGSYVTTADLYCRNDAGTNKKALCLIPKGTTVHNYGYYNVANGVKWLYITVTLDGTEYIGFSSSAYLKKK
Other Proteins in cluster: phalp2_25915
Total (incl. this protein): 397 Avg length: 456,4 Avg pI: 8,23
Protein ID Length (AA) pI
5TtYr 493 8,86016
136AX 502 9,02933
13AyH 474 8,70505
13BJQ 425 8,93985
13E8m 464 9,37720
13GEW 478 8,82477
13caV 434 9,15620
13cjO 388 6,90687
13qdR 424 9,00006
13rY1 421 8,60545
13s9x 424 8,89536
13t36 423 9,18173
1FViU 520 8,96834
1HqCf 426 6,24003
1jUDy 473 5,31885
1kuEM 485 8,85746
1nZOg 473 5,31453
1nhvu 425 9,08980
1nwbZ 485 8,72265
1o1g1 474 5,17879
1o4Pg 371 9,01637
1o9Rb 474 8,78229
1oddz 417 9,01050
1odgT 375 8,82039
1oi4z 485 9,10153
1rmda 486 5,68574
21i7k 480 7,03601
21mcA 455 8,83367
21poB 485 8,79337
21vbK 427 8,38278
23Oah 485 8,85739
24pE8 474 9,17142
24qRa 485 8,86158
291Be 480 8,93050
2VbR3 477 8,94616
2VcXR 478 7,05238
2m9dA 424 8,97975
2mbIz 425 9,09631
2mbL5 473 5,17879
3A4TJ 479 8,46510
3B272 473 5,05966
3TN5h 456 5,15634
3VFDq 422 9,13261
3VIDn 485 8,79350
3VJj4 418 8,69293
3VMGD 421 8,69171
3VMxl 474 9,11095
3WEG6 422 9,24536
3jKJi 473 5,17879
3kMVS 476 8,72684
3kjdt 417 9,06679
3knUq 463 9,12358
3lCTL 463 9,19695
3lcX0 409 8,48038
3lk0t 493 8,74322
3mdQj 463 9,20288
3mwU8 417 9,11333
3nQEW 419 9,03152
3o80f 444 9,29533
3op5x 428 8,56335
3oqiV 375 9,00954
3osdz 425 9,00863
3p3hm 463 9,15092
3p3mA 474 5,23955
3p4c2 375 8,76965
3pBRP 473 5,11894
3pGBV 463 9,15105
3pOEv 424 8,99961
3pbii 427 8,46820
3phei 424 9,05911
3pkKz 463 9,23975
3pszm 473 5,47788
3pxiM 475 9,09638
3pysQ 433 9,10779
3qJ72 463 9,14531
3qNlW 427 8,74425
3qPv4 463 9,15105
3qxSM 485 8,93624
3r0ET 474 8,78216
3rTAP 477 8,60551
3rUCY 474 8,78229
3reZn 463 9,10211
3rq8c 591 8,87067
3rt2o 474 5,12497
3sGOD 427 8,39941
3shjr 417 9,10198
3skzj 424 8,70119
3slUU 463 9,16897
3tOk9 463 9,20281
3tQHY 488 9,23066
3tSL1 375 9,01598
3tUUK 434 8,93978
3tVGj 463 9,15111
3thE0 417 9,15040
3tjv9 496 6,63086
3troR 463 9,30616
3ttmM 315 9,06285
3uNdu 485 9,22506
3ufYs 463 8,97640
3umeW 434 9,03455
3v0NK 424 5,64919
3vxSm 463 8,83941
3w9kn 425 9,00277
3wIO3 425 9,07040
3wLPu 424 8,79047
3wR3m 305 6,47091
3wRPg 463 9,31886
3wRhP 424 9,06498
3wcIi 463 9,25452
3wdRW 417 8,99458
3whv9 425 9,00277
3wwY8 470 4,92410
3xAGy 425 8,91232
3xIK4 474 8,78216
3xIzk 434 8,96254
3xWAK 463 9,15105
3xqQV 470 4,77330
3xzf9 463 8,84418
3y7IV 484 8,81368
3y9xy 433 9,06492
3ykJc 433 8,99961
3yqre 427 8,63994
4114R 422 5,60514
41dbi 428 9,16097
4Lccy 400 4,98065
4QiKn 485 8,64284
4VLhE 463 9,11365
4VRqp 463 9,10792
4VTCq 479 9,14389
4VYg0 485 8,79744
4VyAI 425 9,04171
4y9ZF 489 4,96633
4yjqk 479 5,15094
4ymaN 364 4,97304
4ypL2 484 5,25865
4z8hH 433 9,05892
5C0Vt 474 8,84998
5C0er 415 8,32978
5EUT 442 8,97034
5Kccd 472 5,17879
5L0R9 594 9,27586
5LHJV 475 8,74799
5LVAh 474 8,70086
5La5s 473 5,16510
5LfpK 473 8,97460
5MYKq 473 5,18016
5MlPa 375 8,98349
5Mmdm 425 9,14582
5Mrvm 474 8,78229
5NXXH 474 8,85004
5Njxs 473 5,31453
5Nk8k 473 9,18766
5NnPQ 474 8,70499
5OUw4 588 8,88479
5OyxP 473 5,12224
5POom 477 8,92328
5QCNF 456 8,43790
5QUmZ 473 5,18829
5QlyB 417 8,94952
5Qnae 417 9,15040
5R1cz 524 9,26122
5R8Ic 425 8,73116
5R9Fg 474 8,91980
5RhAy 474 8,60397
5RooY 375 8,91264
5RyW6 425 9,00863
5S13G 473 9,15485
5S4RU 463 8,90394
5SKqB 375 8,93617
5SoRj 477 8,02382
5T2kI 473 5,17879
5TZXn 477 8,91825
5UYvp 424 9,06421
5UZwI 473 5,06460
5VJBM 463 9,15698
5VTbj 475 5,48374
5VlTo 488 7,82164
5VxZg 425 9,09012
5Vzk0 474 8,77790
5WIRB 417 8,80936
5WJ4l 403 8,87332
5WKtH 473 5,11894
5WKu6 473 5,11894
5WjFF 375 8,75818
5WwjV 463 9,20900
5Wwo6 463 9,27405
5X0uM 463 9,31892
5XHrn 425 9,05821
5XyEo 417 9,15040
5Y6RT 524 8,98214
5YAS2 588 8,82200
5YECo 481 8,79615
5Yckg 441 8,01415
5Ydfq 473 5,17561
5YhUD 474 8,77790
5Yqzq 529 9,02630
5YwmW 469 8,88247
5Z9HO 473 5,17879
5ZRvH 473 9,16052
5Zg8q 474 8,61157
5Zipx 496 6,62955
5ZvjJ 422 9,17264
5otyD 473 9,05176
5tUBD 481 8,00718
604AL 425 8,86655
605Fe 469 8,75456
60Qkx 610 9,32124
60rpq 417 9,10198
612wC 474 8,79093
61P5C 474 8,70119
61Sat 473 5,48283
61wM0 479 8,64684
62S25 504 5,49658
62aaZ 473 5,11894
62z3M 424 8,73129
630I1 473 5,11758
63BQ9 471 8,13193
63KYu 492 8,86584
63OL5 528 8,73026
63bL7 424 8,61506
63qXO 417 9,24536
6457L 495 6,61972
64A2U 473 9,15485
64Sqy 474 8,78229
64kvy 463 9,05479
64w9S 474 8,85449
650wi 463 9,08026
65TTG 463 9,26193
65XVk 417 9,15620
66P3s 474 8,78229
66PQf 474 8,61151
66aeH 592 8,99961
66kMD 417 9,20204
67QPI 474 9,05479
67T2H 473 5,17879
67Tlz 433 8,87248
67d4T 417 9,10198
67vgZ 473 9,13203
68MqA 473 5,48283
68e2P 463 8,97131
691kh 479 9,14389
69AIu 473 5,50465
69Svh 474 8,77816
69eeO 417 9,15040
6Anrd 480 5,48629
6Ywvt 385 8,05096
6ZHGj 463 9,04919
6aVHy 425 8,96686
6acaF 477 8,93856
6bLUZ 595 9,00921
6bhcH 473 9,16059
6bs1U 474 5,12497
6cCSb 433 8,93437
6cIt3 474 8,70512
6cRbc 423 9,22731
6chmc 473 5,39399
6dDoF 427 8,31960
6dKSZ 417 9,11333
6dSa3 463 9,21616
6dUuz 474 8,74367
6eUH6 474 8,70512
6edVJ 473 5,11405
6eo4y 424 8,97853
6f01H 479 9,05589
6fANt 473 5,06580
6fF29 463 9,16291
6fP3j 473 9,11314
6g65M 463 9,33620
6g6i0 473 9,13357
6gGzM 463 9,19611
6gXep 510 8,69035
6gjOe 470 4,89056
6goKs 474 8,70099
6gyxg 424 9,12745
6h1TV 474 8,84998
6hEnx 473 5,06460
6hJ3I 473 5,31140
6hhK3 425 9,02920
6huwt 375 8,76378
6if1r 474 8,70099
6izMN 473 9,11875
6j6MQ 610 9,30480
6jGwx 478 8,88956
6jmzX 425 9,08406
6jsb5 473 9,06240
6kgtG 425 8,97840
6kkCs 425 9,18792
6l4XT 479 9,11875
6lEgP 425 8,96686
6lNRJ 425 9,14589
6lPiP 475 8,96905
6lZkr 463 9,03868
6lr2f 473 5,17879
6mSV4 524 9,03139
6mXyF 473 9,02437
6mZc5 473 5,11894
6n2OJ 473 5,17879
6nPqv 551 9,09238
6ngbR 434 9,09586
6nig8 426 7,55546
6oC5V 417 9,04487
6oCPy 592 8,88937
6og2S 475 9,22306
6osp8 473 9,16632
6pGzw 473 5,12491
6pavz 425 8,86655
6pr0U 425 9,14589
6qAmi 591 8,74992
6qF5d 473 5,18016
6qO7X 424 9,00857
6qUlH 417 9,05570
6qbQS 424 8,48180
6qpPs 475 9,07871
6qt43 474 8,92934
6qt7P 481 8,52757
6qxNL 588 8,75431
6r43F 463 9,18508
6rrQE 375 8,86410
6rzhL 473 5,31407
6s1Dm 375 8,61106
6sCND 588 8,75005
6sPPW 473 9,16059
6tS3o 473 5,15913
6tthL 524 9,08090
6u7AY 478 8,61970
6uJbS 529 9,11140
6v0T7 463 9,24607
6vHn1 425 9,05828
6vVU4 463 9,21616
6vqLe 425 8,86655
6wBLP 425 8,86655
6wMEf 473 9,11875
72wCT 480 6,16972
76OfM 483 5,88064
7JBb2 418 8,99742
7M6no 332 8,04238
7NjoZ 463 9,15105
7UkD5 473 5,11894
7X04d 425 8,91367
7X9kf 473 5,38876
7YC8h 475 8,76237
7YcRU 474 8,78242
7aKS9 425 9,09567
7per8 504 5,30583
7plK1 504 5,60554
7q2Gg 434 9,16188
7qBIa 473 5,38876
7qBWw 417 9,11333
7rXVO 463 9,19089
7smoa 417 9,15620
7vF1K 496 6,16887
7xWve 375 8,72729
7yoqf 474 5,24410
82z5i 478 8,43306
84mRm 473 9,15485
89Vsw 463 9,05486
8bB0p 463 9,10779
8cEkJ 463 9,04403
8d8jY 472 8,78229
8eTYv 417 8,97453
8f5iI 591 8,80234
8f6pp 424 9,11391
8fBBj 493 8,97402
8fNcC 475 8,66740
8fjQw 485 8,72639
8gjSk 474 8,58263
8hdZ2 336 5,45208
8iEyL 463 8,97131
8iLAN 473 9,13357
8icdc 410 9,30641
8kP63 463 9,20288
8kUhN 463 9,26193
8lVV7 473 5,17879
8lgMF 474 8,78667
8lkLN 463 9,15111
8mKql 417 8,93927
8mPTM 474 8,50043
8oCQn 463 9,14524
8oeEf 474 8,70512
8qQwX 422 8,25874
8qZFm 478 8,76443
8rGis 498 7,85942
8vBg8 473 5,11161
8vtt3 427 8,04799
NAom 424 8,69635
nq71 426 8,28395
oTBV 457 9,19624
oar5 498 6,36860
osVK 434 9,09090
rnkH 463 9,19688
z8xA 300 6,31660
A0A6B9STL9 301 9,44812
A0A6B9SXM8 308 9,39873
A0A8S5UZS1 472 5,09820
A0A8S5NGU8 221 6,76068
A0A8S5Q6E5 425 9,31331
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24033
810r1
 150 69,0% 336 3.922E-162
2 phalp2_32645
23D70
 91 45,2% 356 2.611E-113
3 phalp2_23993
40d9r
 21 41,6% 334 1.486E-103
4 phalp2_2377
7JCYq
 91 41,9% 348 4.936E-83
5 phalp2_38028
5LT2j
 38 25,9% 408 4.501E-63
6 phalp2_11372
7BXB0
 3 26,6% 435 5.240E-25
7 phalp2_22655
23BKV
 6 25,1% 346 2.912E-23

Domains

Domains [InterPro]
GLUCO
Unannotated
CW_7
Unannotated
Representative sequence (used for alignment): 5TtYr (493 AA)
Member sequence: A0A8S5PSJ4 (250 AA)
1 493 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01832, PF08230

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctt6T3
[NCBI] 		2825282 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015496 [NCBI]
CDS location
range 5700 -> 6452
strand +
CDS
ATGGATAAGGAATTATTTATTCAAAAAGTTGCAGAAAAGGTTAGGAAATATGCACCGTTGTATGGCATCGGTGTACATAGTCCGATTATCGCTCAGGCGATTATTGAAAGTGGTTGGGGTTCTAGCGTGTTAGCTAGTAAATATAACAACTACTTTGGACTAAAGTGTGGCAGTTCTTGGAAAGGTGGTAGTGTTAATATGGCTACCAGAGAGGAATATAAACCGGGAGTTGTCACAAATATAAGAGATAATTTCAGAACATATGAGGACTTCGATGCCGGTATCAGAGGATACTTTGAGTTTATAGGATATTCAAGATATTCTAATCTCAAGGGTGTTACTAATCCTAGAGAGTATTGCGAGAAGTTGAAGTCTGATGGCTATGCTACAAGTAGTTCTTATGTTGACACTCTTATGAGAGTCATTCAGGAAAATAATCTCACAAGATTTGATAATAGTGATAAACCACAATCAGATGTGGATATTGAGAATTTAGCACAGAGAGTTATCAAAGGTGAATTTGGTAGTGGTGAAGAGAGAAAAGCTCTTCTTGGCGGTAACTATGAAAAAGTTCAGCAAAGAGTTAATGAAATTTTAGGTTCATCTAAACCTAAGTATAACATTGATGATTTAGCTAGAAGAGCTATCAGAGGAGAGTTTGGAAATGGTTTAACAAGAAAAGCCAAACTTGAAAAAATGGAACGTGGATTATATGACAAAGTTCAAAAGAGAATCAATGAAATGATGAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0004040 amidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5TtYr) rather than this protein.
PDB ID
5TtYr
Method AlphaFoldv2
Resolution 90.75
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50