Protein

Protein accession
A0A8S5PNB6 [UniProt]
Representative
5KVev
Source
UniProt (cluster: phalp2_14660)
Protein name
Endodeoxyribonuclease I
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRTIKYVAVHCTASRQTMSINELRQEFRRKGWVNPGYHYVVSADGTITQLLPEDKISNGVKGYNSITINVAYIGGIDEHGKPIDNRTEKQKNSLRSLLSMLHKKYPKATIQGHRDFSPDLNKDGKITPNEWIKVCPCFNAKEEYASL
Physico‐chemical
properties
protein length:147 AA
molecular weight:16724,9 Da
isoelectric point:9,36
hydropathy:-0,65
Representative Protein Details
Accession
5KVev
Protein name
5KVev
Sequence length
221 AA
Molecular weight
24755,31170 Da
Isoelectric point
9,35870
Sequence
MQRNTKEWIQYGSAIAVLLLAIILVYISYFTSQARDVTDNVLWYFAQSLMYAGSIFGVASPLMPSSTTSKTNCSIITSKIMRQIKRIFVHCTAGSQSQSIDDLKAEFRRKGWTNPGYHYVIAPNGGIHQLLAIEKVSNGVQGYNSTAINVAYIGGIDAKGKAIDNRTPEQKDALVLLLHKLKQQFPDAQIMGHRDIWGKDKSKWKKMCPCFNAIDEYKDIA
Other Proteins in cluster: phalp2_14660
Total (incl. this protein): 6 Avg length: 153,2 Avg pI: 9,37
Protein ID Length (AA) pI
5KVev 221 9,35870
A0A8S5L697 102 9,18683
A0A8S5PGB8 140 9,61328
A0A8S5SY09 168 9,46030
A0A8S5VWP2 141 9,23776
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11611
1k5JO
 2203 53,0% 149 1.384E-58
2 phalp2_36193
72BPm
 409 38,2% 141 3.429E-37
3 phalp2_23766
13ajC
 287 40,8% 142 8.487E-34
4 phalp2_33574
8Fk8i
 28 35,5% 166 9.163E-32
5 phalp2_3887
6RreM
 7260 35,7% 137 9.834E-30
6 phalp2_25557
3CTPR
 25 35,8% 145 6.371E-29
7 phalp2_26819
3QMwQ
 3 32,8% 143 2.062E-25
8 phalp2_15222
Qitu
 16 28,8% 156 4.006E-23
9 phalp2_19329
8knGF
 9 28,2% 202 1.638E-21
10 phalp2_14613
5sQyS
 2 26,5% 173 1.681E-17

Domains

Domains [InterPro]
Unannotated
Ami2
Representative sequence (used for alignment): 5KVev (221 AA)
Member sequence: A0A8S5PNB6 (147 AA)
1 221 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctnsL8
[NCBI] 		2825666 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015467 [NCBI]
CDS location
range 18816 -> 19259
strand +
CDS
ATGAGAACGATTAAGTATGTTGCTGTTCATTGTACAGCAAGCAGACAAACAATGTCTATAAACGAACTTCGTCAGGAGTTCAGGCGCAAAGGCTGGGTTAACCCTGGCTATCATTACGTAGTATCAGCAGACGGCACTATTACGCAGCTATTACCAGAAGATAAGATTAGTAACGGAGTAAAGGGCTATAATTCTATTACTATAAATGTAGCTTATATTGGTGGTATTGATGAACACGGCAAGCCGATAGACAACCGAACGGAGAAGCAAAAGAACTCTTTGCGCTCGTTGCTTTCAATGCTTCACAAAAAGTACCCAAAAGCAACCATTCAAGGGCATAGAGATTTCTCTCCTGACCTTAACAAGGACGGCAAGATTACACCGAACGAGTGGATAAAGGTGTGTCCATGTTTTAACGCAAAAGAAGAATACGCATCATTATAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0005509 calcium ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5KVev) rather than this protein.
PDB ID
5KVev
Method AlphaFoldv2
Resolution 87.33
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50