Protein

Protein accession
A0A8S5PHE8 [UniProt]
Representative
1Nzv3
Source
UniProt (cluster: phalp2_15386)
Protein name
CHAP domain protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 96% (predicted by ML model)
Protein sequence
MMTAALQPRTREAVLAIAAWQIGVLENPAKSNRQKYGLAAGQNGVAWCMWFVWWVFREAGFNLYKTASCTAFVNRYKAFAPSQLVTKDYKPGDIVFFDFSGKRKKTEHVGIVVGVVGGTILTIEGNTGAGNDANGGAVMKRRRDVSLITCGIRPGYPDPA
Physico‐chemical
properties
protein length:160 AA
molecular weight:17447,9 Da
isoelectric point:9,75
hydropathy:-0,07
Representative Protein Details
Accession
1Nzv3
Protein name
1Nzv3
Sequence length
246 AA
Molecular weight
26728,91860 Da
Isoelectric point
8,58733
Sequence
MATVTELLNIARAEVGTKENPAGSNNVKYNTWFYGRTINGSGYAWCMAFVQWCFNQAKMPLGKVTAGCTTFMNWAKTTGQWYTSNYKPGDVLLFDFDSDKGESEHTGICESVTGNIVNTIEGNTWIGNDTAGGAVMKRQRSTSVIIGAYRPKYDEEKKKDIALGEITSVNGSRGADCLVLLVGKSSTGFNKWGVDVIFDNTGTVLKVVNGGENTTIPSGCYCLSGHGKQTSYLISHYKVGSKIKVF
Other Proteins in cluster: phalp2_15386
Total (incl. this protein): 2 Avg length: 203,0 Avg pI: 9,17
Protein ID Length (AA) pI
1Nzv3 246 8,58733
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_16018
3yVVm
 206 57,6% 156 2.259E-62
2 phalp2_40071
41qFE
 139 44,9% 189 5.399E-44
3 phalp2_24157
2dFjl
 298 42,0% 157 3.906E-31
4 phalp2_17860
jW87
 92 39,8% 163 1.679E-27
5 phalp2_1568
7XJtL
 188 41,2% 172 1.679E-27
6 phalp2_4499
3nCxR
 65 38,1% 173 1.462E-26
7 phalp2_11549
ZJ7o
 17 38,6% 163 8.078E-25
8 phalp2_13419
4ybTO
 2 39,0% 174 8.078E-25
9 phalp2_2684
7236j
 6 34,4% 177 2.390E-23
10 phalp2_33264
5Ekx7
 97 33,5% 161 4.422E-23

Domains

Domains [InterPro]
CHAP
Unannotated
Representative sequence (used for alignment): 1Nzv3 (246 AA)
Member sequence: A0A8S5PHE8 (160 AA)
1 246 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctwDU14
[NCBI] 		2825726 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015421 [NCBI]
CDS location
range 19879 -> 20361
strand +
CDS
ATGATGACGGCGGCGTTACAGCCCCGGACCCGTGAGGCGGTGCTGGCCATCGCAGCGTGGCAGATCGGCGTGCTTGAGAACCCCGCCAAGTCCAACCGGCAGAAGTACGGTCTGGCAGCCGGACAGAACGGAGTGGCGTGGTGCATGTGGTTCGTGTGGTGGGTGTTCCGGGAGGCTGGCTTCAATCTCTATAAAACCGCCAGTTGCACGGCGTTTGTGAACCGATACAAAGCCTTTGCCCCCAGCCAGCTCGTGACCAAGGACTACAAGCCGGGGGACATCGTGTTCTTCGATTTCAGCGGGAAGCGAAAGAAAACGGAGCACGTCGGCATTGTGGTGGGTGTTGTTGGCGGCACGATCCTCACGATTGAGGGCAATACCGGCGCTGGAAACGACGCCAACGGCGGCGCAGTGATGAAGCGGCGCCGGGATGTTTCTCTCATCACCTGCGGCATTCGGCCCGGTTATCCGGATCCGGCCTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1Nzv3) rather than this protein.
PDB ID
1Nzv3
Method AlphaFoldv2
Resolution 93.13
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50