Protein

Protein accession
A0A8S5NZZ1 [UniProt]
Representative
4USyj
Source
UniProt (cluster: phalp2_7513)
Protein name
Peptidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 93% (predicted by ML model)
Protein sequence
MPIDQLDILFVGCAHEIHTYSFRIYIITHIFYFVKEEKSMVSCFKGKFRLTSPRGDRVLNGVKGYHHGIDLVGLDDTTVYSIVDGKVRTGSDNSAGNYVCVTIEDGRRVYYFHLKSFKVKTGDTVKKGQAVGIMGNTGHSFGAHTHLELRVKGTAYKSLDISEFTGIPNKVGVYEYKEDGVKQNKYSYDDTVDAMIQDGVTDLKNMANWEKMLDGREKLEAKYVREIFRRYHEKLNKK
Physico‐chemical
properties
protein length:238 AA
molecular weight:27174,7 Da
isoelectric point:8,88
hydropathy:-0,47
Representative Protein Details
Accession
4USyj
Protein name
4USyj
Sequence length
192 AA
Molecular weight
21050,78370 Da
Isoelectric point
9,60690
Sequence
MMIFKGINRVTQAYGGNHGGIDIVGDTDPTVRCVADGTVYLIQKWDGKTKTGSQSYGNLVIVIDDKKRYYYAHLKSIAVKQGQKVKQGDTIGIMGSTGNSTGPHVHFEVRTGATTATRIDPTPYCGVENRKGVYTEPYRYTSKDGRRALQIAARLAKPTPDDLKLLDMDGDGKITTKDAREVLRKAAKLNVK
Other Proteins in cluster: phalp2_7513
Total (incl. this protein): 3 Avg length: 215,0 Avg pI: 8,48
Protein ID Length (AA) pI
4USyj 192 9,60690
1QrG7 215 6,96990
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_22440
Otxz
 62 43,7% 151 8.372E-35
2 phalp2_5933
67ENK
 29 42,6% 129 1.523E-28
3 phalp2_4480
3h5QZ
 10 36,4% 159 1.314E-24
4 phalp2_14848
7w0BH
 74 42,7% 124 1.929E-22
5 phalp2_5213
453FH
 7 42,6% 143 2.634E-22
6 phalp2_25537
3nGXJ
 39 37,3% 190 4.911E-22
7 phalp2_18623
3ebV
 83 39,5% 134 6.260E-19
8 phalp2_39908
1iVNq
 39 35,9% 181 8.537E-19
9 phalp2_36864
7kPyj
 9 34,6% 202 1.164E-18
10 phalp2_9504
10yNL
 1 37,2% 129 1.652E-16

Domains

Domains [InterPro]
PET_M23
Unannotated
Representative sequence (used for alignment): 4USyj (192 AA)
Member sequence: A0A8S5NZZ1 (238 AA)
1 192 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctiMP24
[NCBI] 		2825621 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015297 [NCBI]
CDS location
range 23511 -> 24227
strand +
CDS
ATGCCAATCGACCAACTTGACATCCTCTTTGTGGGGTGTGCGCATGAAATACACACATATTCGTTTCGTATTTATATTATAACACATATATTCTATTTTGTCAAGGAGGAAAAAAGTATGGTAAGCTGCTTCAAAGGCAAATTCCGTTTGACGTCTCCGCGTGGCGACCGGGTGTTAAACGGTGTCAAAGGCTATCACCACGGCATTGACCTTGTCGGGCTTGACGACACGACGGTATACAGCATTGTGGACGGCAAGGTTCGCACCGGGTCGGACAACAGTGCCGGTAACTATGTATGTGTGACCATCGAGGACGGCAGGAGGGTATATTATTTTCATTTGAAAAGCTTCAAGGTCAAGACCGGCGATACCGTCAAAAAGGGACAGGCGGTTGGAATCATGGGCAACACCGGGCACAGCTTTGGGGCGCACACGCACCTTGAGTTGAGGGTCAAGGGCACGGCATACAAGAGTCTCGATATTTCCGAGTTTACCGGGATCCCGAACAAGGTTGGTGTGTATGAGTACAAGGAGGACGGCGTGAAGCAGAACAAATACAGCTATGATGATACCGTGGATGCCATGATACAGGACGGTGTGACGGATTTGAAGAACATGGCGAACTGGGAAAAGATGCTTGACGGACGGGAGAAGCTGGAGGCGAAGTACGTCAGGGAGATCTTCCGGCGATATCATGAAAAATTAAATAAGAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4USyj) rather than this protein.
PDB ID
4USyj
Method AlphaFoldv2
Resolution 90.45
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50