Protein

Protein accession
A0A8S5NXB9 [UniProt]
Representative
6diyx
Source
UniProt (cluster: phalp2_38047)
Protein name
Cell wall hydrolase autolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKIGLRGGHSPYCKGAMGILDEQAEVRQIYAELKPMLETKGHVVIDCNSNANNVNAELAEGTNKANANNCDVYYTLHMNASKDGSGNGVECWMYDASNEDMNQIADQICKNFKSKGYYNRGKKFNAGYHDLRESAMPAMIIETMFCDNAGDAGRYGSLTAKGIAQLIAEGIDKKAVSGATDVSKPRPENSIVPGAGGLKELGKVDIYSAGFTDRWWPEVKNATDWVGAGDGLPLRYLGFRVTKGSIKVRVYTEASGWLPYIIFGQSYNTNDLDNGVVGDGSPIQAVEMEYLTPEGYKYKYVKYCVSDINNTSFYPAQVDNQRGGGQDGYAGVIGVAADKLIAEIV
Physico‐chemical
properties
protein length:345 AA
molecular weight:37469,7 Da
isoelectric point:5,29
hydropathy:-0,40
Representative Protein Details
Accession
6diyx
Protein name
6diyx
Sequence length
242 AA
Molecular weight
27484,71230 Da
Isoelectric point
8,52938
Sequence
EIVCEGLKAAGYTPGIYASLSWFNNYLGSVRGKYVEWMARYKNLPEDTYKGQYAIWQYASDGQVDGVSGRVDVNHCYMELGGSVAPATPSKPAEKKDLGQVDITYQAFTDRWWPPVVNKIDWAGKGDNVSIKWLAIKVSKGSIRCRVYTRKNGWLPYLTFGNSYDLNDKKNGILGDGSEILAVELYYITPEGYKYKMVHYRVSVQNNKNFYADQVDTLKASGMDGYAGDKYRFIDKFQAWIE
Other Proteins in cluster: phalp2_38047
Total (incl. this protein): 2 Avg length: 293,5 Avg pI: 6,91
Protein ID Length (AA) pI
6diyx 242 8,52938
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_19565
3TIJJ
 398 48,8% 254 1.263E-55
2 phalp2_22108
68XSz
 8 41,6% 156 6.091E-26
3 phalp2_15489
81O6h
 75 36,4% 247 1.335E-24
4 phalp2_432
Orh
 9 30,0% 273 1.358E-20
5 phalp2_7195
3e2lT
 1 35,2% 173 2.506E-20
6 phalp2_22088
5QLBY
 1 33,8% 207 3.612E-15
7 phalp2_29363
150JJ
 9 25,7% 206 3.623E-08

Domains

Domains [InterPro]
GH25
Unannotated
Representative sequence (used for alignment): 6diyx (242 AA)
Member sequence: A0A8S5NXB9 (345 AA)
1 242 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctNU74
[NCBI] 		2825471 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015285 [NCBI]
CDS location
range 2277 -> 3314
strand -
CDS
ATGAAAATCGGTTTAAGAGGTGGACACTCTCCGTATTGCAAAGGAGCAATGGGGATTTTAGATGAGCAGGCAGAGGTGCGGCAAATTTATGCAGAATTAAAGCCTATGCTGGAAACGAAAGGGCATGTAGTAATCGACTGTAACTCAAACGCAAATAATGTAAATGCGGAGCTTGCGGAGGGGACAAATAAGGCAAACGCAAACAACTGCGATGTCTATTACACGCTGCACATGAACGCATCCAAAGACGGAAGCGGAAATGGTGTAGAATGCTGGATGTACGATGCATCAAATGAGGACATGAATCAGATTGCAGATCAGATCTGCAAGAATTTTAAGTCAAAAGGATATTATAATCGAGGTAAAAAATTTAATGCAGGATACCACGATCTAAGAGAATCTGCAATGCCGGCAATGATTATAGAGACAATGTTTTGCGACAACGCAGGAGATGCTGGAAGATACGGAAGTTTAACAGCAAAAGGAATTGCGCAGCTGATTGCGGAAGGGATTGATAAAAAGGCAGTATCTGGAGCAACGGACGTTTCCAAACCGAGACCAGAAAACTCTATTGTACCGGGAGCTGGCGGATTAAAAGAACTTGGAAAAGTAGATATATACTCCGCAGGTTTTACTGATCGGTGGTGGCCGGAAGTTAAAAATGCCACAGACTGGGTTGGGGCAGGAGATGGACTACCACTCCGGTATCTTGGATTTAGAGTAACTAAAGGATCTATAAAAGTAAGAGTGTACACGGAGGCGAGCGGATGGCTGCCATATATCATATTTGGCCAGTCTTACAACACAAATGATCTTGATAACGGTGTTGTTGGAGATGGATCACCGATTCAGGCAGTCGAGATGGAATACCTTACTCCAGAGGGATACAAGTATAAGTATGTAAAATACTGTGTATCAGACATTAACAATACATCATTCTATCCAGCACAGGTAGACAATCAACGCGGTGGTGGCCAGGATGGGTATGCAGGAGTTATTGGAGTAGCAGCAGATAAGCTTATTGCTGAGATTGTGTAG

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6diyx) rather than this protein.
PDB ID
6diyx
Method AlphaFoldv2
Resolution 90.56
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50