Protein

Protein accession
A0A8S5NN92 [UniProt]
Representative
8lvpW
Source
UniProt (cluster: phalp2_12804)
Protein name
Peptidoglycan hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSIENMISWMTSKEGRITYSMTNRLGPNSYDCSSAVFFSLIAGGYLPKGSMGNTETLFAMNGTFFKKISRAEVRRGDIFIAGTPGASHGSEGHTGIFLSNKSFIHCSYYWNGIHTDSHDSYMSTRLPHHFYRIVASGSADVNTDNSAQMIKLAIDGQWGPLVTLRLQEYYNTTRDKVISHQYKQKYNKNIYSAEFDITLIGSDVIRAIQMGLKAKGYYTGSIDGLCGEATIKAMQKALGTTVDGVISPQSDMVKALQRALNNNKLPW
Physico‐chemical
properties
protein length:267 AA
molecular weight:29593,3 Da
isoelectric point:9,10
hydropathy:-0,29
Representative Protein Details
Accession
8lvpW
Protein name
8lvpW
Sequence length
119 AA
Molecular weight
13298,20860 Da
Isoelectric point
9,23885
Sequence
MIKLAIDGQWGPLVTLRLQEYYNTTRDKVISHQYKQKYNQNIYSAEFDTTLIGSDVIRAIQMGLKARGYYSGVIDGLCGEATIKAMQKALGTTVDGIISPVSDMVKALQRALNNNKLPW
Other Proteins in cluster: phalp2_12804
Total (incl. this protein): 5 Avg length: 144,2 Avg pI: 7,99
Protein ID Length (AA) pI
8lvpW 119 9,23885
7BMNE 88 9,77426
7sSWe 121 5,12150
7tQI5 126 6,71384
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_22714
8cFAE
 4 43,6% 87 7.463E-22
2 phalp2_1816
3ebwD
 3 37,8% 119 3.012E-19
3 phalp2_12018
7MMHs
 20 39,4% 114 7.767E-19
4 phalp2_17621
6Hjw9
 1 30,0% 120 1.140E-06
5 phalp2_4815
5dJYJ
 2 24,7% 89 5.441E-06
6 phalp2_39082
2bOI7
 1 25,5% 90 1.388E-05
7 phalp2_11337
7m8rw
 6 32,6% 92 2.290E-04

Domains

Domains [InterPro]
PG_1
Representative sequence (used for alignment): 8lvpW (119 AA)
Member sequence: A0A8S5NN92 (267 AA)
1 119 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ct1is2
[NCBI] 		2826273 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015204 [NCBI]
CDS location
range 13875 -> 14678
strand +
CDS
ATGAGTATTGAAAATATGATTTCATGGATGACAAGCAAGGAAGGGCGAATCACTTATTCTATGACAAATCGCTTAGGACCGAACAGTTATGATTGTTCCTCCGCAGTGTTCTTCTCGCTGATCGCAGGAGGTTACTTGCCAAAAGGGTCAATGGGTAACACCGAAACATTATTTGCCATGAATGGGACATTCTTTAAGAAAATTAGTCGTGCAGAAGTGAGGCGTGGTGATATCTTTATCGCTGGGACTCCTGGGGCTTCTCATGGATCAGAAGGGCATACCGGTATCTTTTTAAGCAACAAGAGTTTTATTCATTGCAGCTATTACTGGAACGGAATTCACACAGACAGCCACGATTCTTACATGAGTACGCGATTACCGCATCATTTCTATCGAATTGTAGCTAGTGGTAGTGCAGATGTGAATACTGACAACAGTGCTCAAATGATTAAATTGGCGATTGATGGTCAGTGGGGACCACTCGTTACTTTACGTTTGCAAGAGTATTACAACACTACTCGTGATAAAGTGATTAGTCATCAGTACAAGCAAAAGTATAATAAAAATATCTATTCCGCAGAATTTGATATCACATTGATCGGTTCTGATGTTATTAGAGCTATTCAAATGGGGCTAAAAGCTAAAGGATATTATACTGGTTCAATTGATGGTCTATGTGGTGAAGCAACAATCAAAGCGATGCAAAAAGCATTAGGAACAACGGTTGATGGTGTTATCAGTCCGCAATCTGATATGGTTAAGGCTTTGCAACGAGCATTGAACAATAACAAGCTTCCATGGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8lvpW) rather than this protein.
PDB ID
8lvpW
Method AlphaFoldv2
Resolution 98.08
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50