Protein

Protein accession
A0A8S5NBQ3 [UniProt]
Representative
69UWv
Source
UniProt (cluster: phalp2_2535)
Protein name
Morphogenesis protein 1 hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKAGQKLVYNGSEVCLFPMETMNITQWSSPTAESHCCGHPFDNAINGQVRVPVYAPFSCHLSYSDSVGNTRAYSSDNPVWTPNGLTYVTVSFTHDPNPPTATRYAQGDLIYHTGEAGYATGDHCHIDQTFTQNAGLVYYGVTCRYGNQCYALSGSVLPTEVFYINDTNIVNGYGQRWKTFEGGEPPAPEPQYKYIKHYFILDGLGIDLGFYKTKEEILPEPPTPTGKWVIPGDINNTRPLTEDESKQNWVAFWQFFKAKGWTANAVAGMLGNAYFESTVNPNRWEGDIPFAQPVASRGYGLVQWTPWTNIINWLKDKGYYPDVSKFGLGECERIQWEMENGAQWIATATYPESFASFSKSTADPYTLAIEFLANYERPLDPNQPTRGTKAREIYDYIKDK
Physico‐chemical
properties
protein length:400 AA
molecular weight:45025,6 Da
isoelectric point:5,17
hydropathy:-0,51
Representative Protein Details
Accession
69UWv
Protein name
69UWv
Sequence length
394 AA
Molecular weight
44547,34850 Da
Isoelectric point
5,23751
Sequence
MKPNEKLSYKGYQVCLFPMETMYITQWSSPDSYSHCCGHPFDCAVGGRTDVPLYAPCDCHLINADSAQNGNTRIYTSDKKVWTPSGLRQVTFSFTHDNNPPTKTTFKQGELIAHTGVAGMVTGDHSHIDQTFTVDGTLISYGITCSFGNECYALNGSVLPTLFWYVNDTVIENDMGHTFSTFKKGKPSYDTLEWVITNSSLTEPSRPLTDEEMKNNAKCFYGTMNILYGWTLNACCGVLGNMQSESTISPCRWQNDTPYGTPTESQGYGLAQWTPYTKVLDWLRDNGFLIQNFGEGECARMNYEVATNTQWIATSAYPESFKEFTQSKGNPYDLAIEFLANYERPADPNQPIRGTQAEQWYQYLKDWKPVLPGSGDIEPEKKKSKWIYYMGRPF
Other Proteins in cluster: phalp2_2535
Total (incl. this protein): 137 Avg length: 400,8 Avg pI: 5,24
Protein ID Length (AA) pI
69UWv 394 5,23751
1keMI 400 5,32174
2Iiu 400 5,08404
3Id3f 400 5,13850
3p9rJ 394 5,56268
3pSVl 400 5,58940
3rOJQ 404 5,00828
3rQ7Z 401 5,02379
3rmdc 404 4,96508
3toVF 401 4,87391
3torG 401 5,30492
5JZ1v 394 5,59963
5KKCI 400 5,15134
5Kf7V 334 5,58218
5LGGV 400 5,14424
5LkL6 401 5,25683
5M16X 401 5,57382
5OK7O 400 5,07080
5P8Kq 400 5,14031
5Px02 400 5,23597
5Qqyn 404 5,38023
5RXF3 373 5,68881
5SAzt 400 5,09700
5SInv 400 5,23546
5Sezz 401 5,29372
5T0oM 404 5,02260
5TXxu 400 5,58082
5Tzg5 404 5,28878
5TzgD 404 4,98605
5UxCB 402 5,61464
5VQIo 404 5,38796
5VrmS 398 5,14424
5WAnc 394 6,15148
5WFwx 402 5,08677
5WVoh 402 5,30015
5X3LG 403 5,28878
5XO8p 400 5,31572
5XobJ 405 5,30986
5YelC 400 5,48140
5YzP8 400 4,93836
5ZE1s 400 5,30492
5ZNM6 400 4,86806
5ZfkT 497 5,34766
5Zptg 401 5,15890
608l4 401 5,48510
60OHt 321 5,70365
6112l 400 5,56047
62Kxz 401 5,30958
62O1k 404 5,16146
63aBf 400 5,21318
642CZ 400 5,23546
64KsA 400 5,30941
64PrH 400 5,23694
64ScF 400 5,15685
64UgK 400 5,30492
64UhQ 400 5,10536
64wX2 320 5,54035
65EK9 402 5,37159
65ypS 401 5,00828
6652M 403 5,48510
66kYE 400 5,30015
66vJk 400 5,55365
67zsK 400 5,38967
684OF 404 5,56962
689XV 373 5,57388
68GXd 406 4,56669
68HEC 404 5,30981
68P59 404 5,08677
68gUy 404 5,58508
68mf2 400 5,15691
695e5 404 4,99361
69bxL 400 5,24189
6a2iM 404 4,96383
6b3sp 406 4,56669
6bBCc 401 5,39359
6bNWq 394 5,92373
6bNXK 400 5,31572
6bPnB 405 5,05221
6cC1R 406 4,61080
6cYBM 401 4,97281
6chj3 401 5,30492
6d10C 401 5,09126
6d5BB 399 4,98230
6daX4 405 5,13702
6dpgm 400 5,21852
6eWx0 399 4,99924
6ec28 406 4,46075
6eeJN 400 5,15685
6egCA 402 5,29861
6f8CF 401 5,08825
6fJfU 400 5,27076
6fKA8 465 4,91006
6fNQV 394 5,52869
6gBJ5 376 5,48942
6i4Q7 394 5,30310
6i6hM 404 5,02953
6jfhc 399 5,20619
6jmp1 401 5,05773
6k7dq 401 5,30333
6kA3X 402 5,48510
6kCzB 401 5,02175
6mAh0 404 5,37932
6mxMT 407 4,86874
6nB5i 403 5,49078
6nGAQ 401 4,94507
6o6Ys 400 5,24189
6oJRS 394 5,43588
6oM0r 406 5,50573
6pxVW 400 5,23921
6q2vM 382 5,22637
6q4B9 401 4,81883
6qGSx 400 5,48277
6rTzH 404 4,96633
6siyW 401 5,21852
6tXcu 401 5,39359
6vypN 413 5,39228
6wzcw 406 4,54589
7W0Nj 400 5,38285
7WPUC 400 5,24069
7ZIQO 497 5,47816
7Zhsl 406 4,66548
81l5E 430 4,55504
83vSa 417 5,55916
84M9t 406 4,54129
84hke 400 5,48879
88Yi6 402 5,40893
8bAYT 394 6,24930
8bBBR 399 5,12480
8dg1R 389 5,58235
8k19t 406 4,54748
8lULQ 406 4,57278
8lUxq 393 5,88911
8oOS9 403 5,02277
8oPoe 402 5,46685
8svLg 401 5,52489
a27w 391 5,53239
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_35180
60OI3
 5 84,7% 275 8.473E-149
2 phalp2_18428
6exQW
 65 29,6% 317 9.313E-29
3 phalp2_14324
3WNLt
 2 26,9% 404 1.091E-26

Domains

Domains [InterPro]
Unannotated
Phage_lys2
Disordered region
Representative sequence (used for alignment): 69UWv (394 AA)
Member sequence: A0A8S5NBQ3 (400 AA)
1 394 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF18013

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctTZV6
[NCBI] 		2826556 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015127 [NCBI]
CDS location
range 11607 -> 12809
strand +
CDS
ATGAAAGCCGGTCAAAAGTTAGTTTATAATGGCAGTGAAGTCTGTTTATTTCCAATGGAGACAATGAACATTACACAATGGTCTAGTCCAACAGCTGAGTCACATTGCTGTGGACATCCATTTGATAATGCGATCAATGGGCAGGTCCGTGTACCAGTTTACGCTCCTTTCAGCTGTCATTTATCGTATAGTGATAGTGTAGGAAATACACGTGCGTATAGTTCCGACAACCCCGTATGGACTCCCAACGGGTTAACATATGTTACAGTTAGTTTTACACATGACCCGAACCCACCAACCGCAACAAGGTACGCGCAAGGTGATTTAATTTATCACACAGGTGAAGCCGGATATGCTACCGGAGATCATTGTCATATCGACCAAACTTTTACACAGAATGCCGGATTAGTCTATTATGGTGTTACATGCAGATATGGCAATCAATGTTATGCGTTAAGTGGTTCAGTTCTACCAACGGAAGTATTTTATATAAATGATACAAATATTGTAAATGGATACGGTCAACGATGGAAAACTTTCGAAGGCGGAGAACCACCAGCACCCGAACCACAATACAAATATATTAAGCATTATTTTATTTTAGATGGTTTAGGAATTGACCTAGGCTTTTATAAAACAAAAGAAGAAATACTACCCGAACCACCGACGCCAACAGGCAAGTGGGTTATTCCTGGGGATATTAATAACACAAGACCACTAACCGAAGATGAGTCCAAACAAAATTGGGTTGCTTTTTGGCAGTTTTTTAAAGCTAAGGGATGGACCGCAAACGCGGTTGCTGGCATGTTAGGAAACGCTTATTTTGAAAGCACGGTTAACCCGAATCGTTGGGAGGGTGATATACCTTTTGCACAGCCGGTTGCTAGTCGTGGATATGGTTTGGTTCAGTGGACGCCTTGGACGAATATTATAAACTGGCTAAAAGATAAAGGATACTATCCGGACGTTTCAAAATTTGGGTTGGGTGAGTGTGAACGAATCCAATGGGAAATGGAGAATGGCGCACAGTGGATAGCTACAGCAACCTACCCCGAAAGTTTCGCGAGCTTTTCAAAATCAACCGCCGACCCTTATACATTAGCGATAGAATTTTTAGCCAACTATGAAAGACCGCTAGATCCTAACCAGCCAACGCGTGGCACGAAAGCGCGTGAAATTTATGATTATATCAAAGACAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0016787 hydrolase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (69UWv) rather than this protein.
PDB ID
69UWv
Method AlphaFoldv2
Resolution 88.30
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50