Protein

Protein accession
A0A8S5N8U2 [UniProt]
Representative
76YNm
Source
UniProt (cluster: phalp2_30701)
Protein name
NlpC/P60 family
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MTATMAAIQTDKAIQWALKIAQDPSHGYDQTKRWGPDYDCSSFLITAWDQAGVPLIKAGATYTGNMRKAMLKNGFRDVTSTVDFATGAGLCRGDILLNEQHHVAMYIGNGQIVHASINERGRATGGKTGDQTGREICVRSYYVYSKGWQKVLRYKGSGKEEVRKVKQYAGIVKVSSYLNVRTGAGTENPVMKIGDQDFRLPAGMVVSIEAEKGGWGKLTNIGGWVCLDYIKK
Physico‐chemical
properties
protein length:232 AA
molecular weight:25436,8 Da
isoelectric point:9,41
hydropathy:-0,37
Representative Protein Details
Accession
76YNm
Protein name
76YNm
Sequence length
307 AA
Molecular weight
33139,61380 Da
Isoelectric point
8,70235
Sequence
MELFNEEVENEVTKTEKAVTWAVGIANDDSHGYDQGANRWKQDYDCSALVIQAWEQAGVPVKTAGATYTGNMKKIFLANGFADVTKSVNLTTGAGLQRGDVLLKEARHTAMSIGSGQIVQASINEKGGATGGRVGDQTGREIWTRSYYNYTGGWDCILRYTGDPATTGKTLDELAREVLAGKWGSGDARKQALTAAGYDYKAVQTRVNALLKGGTTAVKPAVTYTPGQTCTVNISLNVRTGPGTNYRKKKHSELTASGQQADSTRTGVMDPGTKVTCKEIQLDGENIWIRTPSGWLAAYYNGKQYIN
Other Proteins in cluster: phalp2_30701
Total (incl. this protein): 80 Avg length: 264,6 Avg pI: 7,70
Protein ID Length (AA) pI
76YNm 307 8,70235
13AJt 224 9,27708
1d7qv 258 8,80330
1gIlF 239 9,33671
1gJAX 292 9,18470
1k2Tn 244 9,12423
21Akc 239 4,86561
21HuO 245 9,01012
239dt 244 4,93103
23aCW 244 9,28076
23uXn 243 4,82781
24I4g 248 9,42536
2VaLn 247 9,36340
2VbUf 244 9,31415
2Vboj 305 6,10413
2VcfE 246 9,19798
2Vd39 249 9,65441
2VjLs 247 9,53109
2VkvX 235 9,28965
2Vnrt 249 9,78200
3GQ9x 232 6,04815
3Jc6Q 301 6,53656
3lI7r 339 9,34864
3lNRu 232 6,04815
40dYP 233 9,09689
4ysBd 243 4,61501
4yuIT 243 4,65616
5HJch 299 9,23099
5M51t 301 6,23554
5MltZ 232 5,88223
5PyLA 232 6,04815
5QbT7 301 6,53497
5RQop 339 9,40337
5S52g 280 9,31170
5W2Sf 301 6,53656
5Wy0q 334 9,32588
5YPGE 300 6,96342
5ZXRE 300 6,53639
5oKEF 255 9,68110
5tDX8 249 9,28082
60Aqz 241 9,17322
62YCx 226 6,22685
66U11 232 6,04815
67Zzk 232 5,57320
685vN 301 6,23799
6HAnq 253 9,57531
6HzRU 253 9,57499
6amvD 301 5,99818
6cesl 232 6,04962
6dpg0 232 6,22867
6elSB 232 5,72212
6elqs 232 5,87996
6hp65 300 6,96439
6k8Wj 232 6,22867
6ljbT 232 6,04127
6nO8r 338 9,34864
6niJ5 325 9,20797
6nmhD 232 6,04815
6qNWf 232 5,88343
6t8b2 301 6,23810
6v0Jh 301 6,53372
7OGth 338 9,34864
7XtAY 339 9,30874
7aKQv 279 9,19366
7pZUA 248 9,59111
7uCVT 303 9,45617
7zqif 338 9,24859
81O8l 251 9,64404
81lfA 236 5,47169
82nUx 254 9,48834
84bYP 280 9,17967
87QZu 295 4,64968
8fjam 196 8,98401
8jqP3 303 9,51710
8lKzE 232 6,04815
8mKZn 232 6,04815
8rAPv 295 4,66588
8vrUt 232 6,22867
obsN 233 9,68936
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36427
10262
 294 58,5% 193 2.858E-71
2 phalp2_30104
38LMY
 4 42,7% 201 3.427E-39
3 phalp2_21505
8k22n
 3 27,5% 225 2.566E-22
4 phalp2_30683
6W6ka
 7 26,6% 214 3.758E-18
5 phalp2_36439
13b8a
 1 23,2% 267 2.691E-14
6 phalp2_4897
5Vd10
 91 23,8% 306 9.423E-08

Domains

Domains [InterPro]
Unannotated
CW_7
Unannotated
Representative sequence (used for alignment): 76YNm (307 AA)
Member sequence: A0A8S5N8U2 (232 AA)
1 307 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF08230

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctiBE32
[NCBI] 		2826685 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015088 [NCBI]
CDS location
range 7538 -> 8236
strand -
CDS
ATGACGGCAACAATGGCAGCAATACAAACGGATAAGGCTATACAGTGGGCCCTCAAGATCGCACAGGATCCGTCGCATGGATACGACCAGACAAAGAGATGGGGGCCCGATTATGACTGCTCCTCGTTCCTGATTACAGCATGGGATCAGGCAGGAGTGCCTCTGATTAAGGCAGGGGCCACCTATACGGGGAACATGCGGAAAGCGATGTTGAAGAACGGCTTCCGGGATGTAACGTCCACTGTGGACTTTGCAACAGGGGCCGGGCTCTGCAGAGGCGACATCCTGCTGAACGAACAGCACCACGTCGCAATGTACATCGGGAATGGTCAGATCGTCCACGCAAGCATCAACGAGAGAGGACGTGCAACCGGAGGCAAGACCGGAGACCAGACGGGGCGTGAGATTTGCGTCCGGAGCTACTATGTCTACTCAAAAGGATGGCAGAAAGTACTCCGATACAAGGGATCCGGAAAGGAAGAGGTACGAAAAGTGAAGCAGTACGCAGGGATTGTCAAGGTCAGCAGCTATCTGAATGTAAGGACCGGAGCAGGGACAGAGAATCCTGTGATGAAGATCGGAGATCAGGACTTCCGGCTTCCGGCAGGCATGGTCGTGAGCATTGAAGCTGAGAAAGGCGGCTGGGGCAAGCTTACCAATATTGGCGGCTGGGTGTGCCTCGATTACATAAAGAAATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (76YNm) rather than this protein.
PDB ID
76YNm
Method AlphaFoldv2
Resolution 86.44
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50