Protein

Protein accession
A0A8S5N7Q6 [UniProt]
Representative
1ntYC
Source
UniProt (cluster: phalp2_12591)
Protein name
Morphogenesis protein 1 wall, phi29, hydrolase, infection
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MNANALEVYKYLSARGWSLNAIAGLLGNMQSESYVNPGVWQSLQANNYSGGFGLVQWTPATNYTDWARQNGYDIADPNGQLYWIDALSETTGQWIPTSAYNMSWSAFKKSGSSPEELASAFLKNFERAGVEVESNRRSQARSYFNLLGQYGKNAKAVESAVQWAIGIANDNSHGYDQGSRWGPDYDCSSLLITAYQQAGIKVKDAGATYTGNMYSAFLACGFEDVTGFVNLSNGSGIKRGDILLNTASHTAMSIGNGQVVQASQNELGGATGGQSGDQTGREIWCTNYYNFPWNYVLRLSHSESGGSSGGASAYIVKWIPG
Physico‐chemical
properties
protein length:321 AA
molecular weight:34702,7 Da
isoelectric point:5,25
hydropathy:-0,39
Representative Protein Details
Accession
1ntYC
Protein name
1ntYC
Sequence length
337 AA
Molecular weight
36797,91410 Da
Isoelectric point
4,98247
Sequence
MAWTIGNMVLSQSQMDANAVEVYKYFSAKGWTLNAIAGICGNMQSESWLNPGVWQSLKEGNYSGGFGLVQWTPATNYTNWASTNGYGITDPNGQLYWIDALSGSSGQWIATSAYNLSWSAFKKSSQTPEWLASAFLKNFERAGAEVEATRQSQARYYYNLLSQYDTNSKAVESAVQWAINIANDDSHGYDQTHRDGPNYDCSSLICWAYYQAGLNTRPGYTPATGTMYNVFLAAGFEDVTSSVNLTTGEGVQRGDVLLNTVHHTAMSIGNGQVVNASQNEHGGATGGTTGDQTGKEIYIRNYYNYPWNYVLRLPGGSSGNGGTTEAEGIYIVRWIPG
Other Proteins in cluster: phalp2_12591
Total (incl. this protein): 157 Avg length: 331,6 Avg pI: 5,19
Protein ID Length (AA) pI
1ntYC 337 4,98247
1FCK7 335 4,78450
1kXM3 330 5,79891
1kjhG 325 4,48280
1mZ46 332 4,52560
1n8av 329 5,57610
1ngVw 332 5,07052
1oidL 332 4,75773
1oj64 340 5,02914
2l4sf 358 8,26293
2m3mg 332 4,78257
2mxYN 349 4,99788
3C5jR 332 5,39529
3GNDt 335 5,26303
3jIbe 323 5,80783
3jVh7 342 5,04573
3jVjJ 335 4,95275
3jVtt 353 5,12576
3k6IL 332 4,43534
3kHY3 332 4,52844
3kNxf 339 5,02965
3kQ39 339 5,41081
3knqk 334 6,23787
3lFTE 322 4,41880
3lddL 333 5,37165
3lmmW 339 5,77339
3m1Zu 337 4,76114
3mmyg 339 5,20198
3mr5R 332 4,74324
3p3Hc 332 4,66895
3p4mb 305 4,89812
3pvdr 329 4,68310
3qukg 323 5,35914
3rdqf 333 4,90187
3rjqr 274 5,26161
3s8gG 332 5,18306
3sAcf 333 4,61751
3sum2 332 5,18306
3t3Vv 332 4,76370
3uf1c 328 5,29889
3umZB 332 4,63621
3wEra 333 5,22779
3wwRa 333 6,06969
3xMjU 333 5,37904
3xNhV 332 4,71124
3xz7V 332 4,63621
4L1uN 360 6,24822
4SEpk 339 5,04272
4VBGu 325 4,34946
4VtFn 332 4,43534
4VytF 333 5,01459
4z4Pn 318 4,85140
5LErx 328 5,09848
5M3LA 332 4,50588
5Ndlp 335 5,11428
5Ndy9 339 5,09848
5ODsy 333 5,23643
5OSaX 332 4,57840
5P6Z9 328 5,10928
5QgU0 340 4,90540
5SBI6 358 6,26811
5TM9h 329 5,72757
5UU4v 358 7,71262
5Uz96 325 4,37611
5VkQa 332 4,81366
5YkmI 333 5,55314
5YlTL 332 5,41792
5Zt3F 332 5,29764
5Zv2x 332 4,94780
5i2LH 306 4,06509
5zEY 335 4,98571
61iur 339 5,30662
63QwP 332 4,80809
63snY 335 5,11428
64f5Q 340 5,11309
65T1f 358 7,71285
66hud 340 4,91569
67EgD 318 5,58417
68MRl 328 5,50710
68Z4q 344 6,46415
68hRR 358 7,09404
68tVw 332 4,86590
69ssh 339 5,02965
6YIII 339 5,30662
6aD4s 328 5,41598
6ajHU 339 5,19346
6bIqR 329 5,57610
6beKU 331 5,11428
6d24j 339 5,09848
6doay 332 4,74324
6eMx1 332 4,50781
6eMzq 332 4,81321
6eRNV 344 6,72010
6eX4y 325 4,40493
6eneL 335 5,12747
6exLD 332 4,85061
6ghvS 332 4,77046
6gmBL 328 5,28480
6iRrR 329 5,58389
6jGR1 332 4,47882
6k50e 333 5,87456
6k9KC 332 4,85549
6kFC1 333 5,55314
6m7C0 339 5,11468
6m8EF 334 5,74161
6mqT7 325 4,41880
6nioY 321 4,86669
6oCXb 332 4,72181
6px5h 340 4,91569
6qlTa 332 4,50781
6sgvb 243 4,97150
6uOiu 332 4,63621
6uqYb 344 5,30896
6wJAU 323 5,55586
6wRFt 333 5,22779
79FbJ 335 4,79894
7BZoO 332 4,67492
7Geji 321 5,95516
7KzNK 328 4,49690
7MdEN 332 5,43264
7QJJX 335 4,78450
7p3qw 327 4,43636
7pfwW 322 4,68577
7su2W 341 5,01226
7t3HD 331 5,29213
7t7xQ 339 5,30662
7tBFT 332 5,10519
7tQuc 332 5,18630
7uCKH 332 4,67213
7viYf 349 4,99788
7viZY 335 4,79894
7vj0q 342 5,07950
7vj6E 332 4,44813
7wHZE 341 5,01947
7xGeP 335 5,12485
7zqcH 341 5,40723
82sKp 358 7,71648
82z73 339 5,29889
85Hnc 334 4,69350
8dftQ 329 4,78126
8fJxi 332 4,40738
8jQyJ 342 5,00191
8lfs3 358 8,26293
8lg4i 327 5,91338
8lovR 332 4,66895
8q4tf 332 4,41977
8qUiX 334 7,69824
8r3C3 339 5,21796
8rA2s 246 5,10303
8rMiJ 332 4,48240
8rlh7 358 7,71262
8sI5Z 339 5,09848
A0A8S5NAE0 328 4,55845
A0A8S5NXH8 325 4,41880
A0A8S5TDN0 164 5,11462
A0A8S5VWM2 333 5,10678
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_2108
3dVmz
 7 38,0% 344 1.334E-82
2 phalp2_4279
86H4N
 25 26,7% 352 6.031E-50
3 phalp2_8091
6rym4
 4 29,3% 300 1.271E-33
4 phalp2_34740
3dP2O
 18 22,4% 401 2.034E-27
5 phalp2_13483
4MI6v
 2 21,2% 277 2.109E-15
6 phalp2_6365
7wKVL
 5 22,3% 260 9.249E-14
7 phalp2_803
3ulFn
 191 22,5% 359 7.014E-13

Domains

Domains [InterPro]
Phage_lys2
Disordered region
Representative sequence (used for alignment): 1ntYC (337 AA)
Member sequence: A0A8S5N7Q6 (321 AA)
1 337 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF18013

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctRlj31
[NCBI] 		2826338 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015081 [NCBI]
CDS location
range 9350 -> 10315
strand -
CDS
ATGAATGCAAATGCGTTGGAAGTGTATAAATATCTCTCAGCAAGAGGATGGTCGCTAAATGCAATTGCTGGATTGCTTGGCAATATGCAGAGTGAGTCCTATGTCAATCCTGGAGTGTGGCAGAGTTTACAAGCGAACAACTATTCGGGTGGGTTTGGTCTTGTGCAGTGGACTCCTGCCACGAATTATACGGACTGGGCGCGCCAGAACGGATATGATATTGCAGATCCGAACGGTCAGCTGTATTGGATTGACGCCTTGTCGGAGACGACAGGACAGTGGATTCCAACAAGCGCTTACAATATGTCGTGGAGCGCATTTAAAAAGTCAGGATCCTCGCCGGAAGAACTCGCCAGTGCATTCCTCAAAAATTTTGAACGCGCCGGAGTAGAGGTTGAGTCCAACAGACGGTCACAGGCTCGGAGTTATTTTAATTTACTCGGTCAGTACGGTAAAAATGCCAAAGCTGTAGAGTCTGCAGTTCAATGGGCGATTGGAATTGCAAATGATAATAGTCACGGATACGATCAAGGGAGTCGCTGGGGTCCAGACTATGACTGCTCCTCATTACTGATCACTGCCTATCAGCAAGCCGGAATCAAGGTTAAGGATGCCGGTGCGACATATACCGGAAATATGTACTCTGCATTTTTAGCGTGTGGATTTGAGGATGTGACAGGATTTGTCAATCTGTCAAATGGTAGCGGAATAAAGCGAGGAGATATCTTACTAAACACAGCAAGCCACACTGCTATGTCGATCGGCAATGGTCAAGTAGTACAGGCGAGCCAGAATGAGCTTGGCGGTGCTACGGGAGGTCAGAGTGGTGACCAAACAGGACGAGAAATATGGTGCACGAATTATTATAATTTCCCGTGGAATTATGTCCTGAGATTGTCGCACAGTGAATCAGGCGGATCGTCAGGCGGAGCATCAGCGTATATCGTCAAATGGATTCCAGGGTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1ntYC) rather than this protein.
PDB ID
1ntYC
Method AlphaFoldv2
Resolution 92.32
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50