Protein

Protein accession
A0A8S5N5R1 [UniProt]
Representative
5RDQF
Source
UniProt (cluster: phalp2_32076)
Protein name
Cell wall hydrolase autolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MVNNMKINVHAGHNPDGKIACGAVGLIKESTEARKVKKEVIRLLKKKGHKAYDCTCTNGTSQADVLKRIVTKCNKHKVDLDVSIHFNAGAGDKKGNGKTTGTEVYVYSSTSAAKPAAERVVKEIVALGFKNRGVKIRTDLYVLHRTNSPAMLIECCFVDDKDDVELYDYKKMAAAIVAGILGLKA
Physico‐chemical
properties
protein length:185 AA
molecular weight:20091,2 Da
isoelectric point:9,43
hydropathy:-0,26
Representative Protein Details
Accession
5RDQF
Protein name
5RDQF
Sequence length
390 AA
Molecular weight
42313,03070 Da
Isoelectric point
9,53489
Sequence
MASYNIHGGHNPKGKIACGAVGLLDESEQDRIIKNKVISILRANGHTVYDCTEDNGTSQSDVLKKIVAKCNVHKVDLDVSIHFNSGANDTNGNGTTTGSEVWIYKNSSSSKTAAQRIVNNLASVGFKNRGIKTSTGLYVLRKTKSPALLVEVCFVDDKDDYNLYINNVDRIAKAIADGIVGATLSSGNNAPSTPNPTPTTTNQLYRVRKSWSDVKSQTGAYKDISNAKRECPNGYSVFDSNGNVVYTNGTIQATNTAPTVTAKPSAPASSSSTTSKYYLANARVRGWQSAMNKGFDLKGNNKLVVDGKFGEASQSCASSHNLWSGQKHNCPTAIKWLRKTLHDTYRFTKLPITGKWDAYLTTCVKVFQKNRGLTQDGRVGLVTTYYLLKG
Other Proteins in cluster: phalp2_32076
Total (incl. this protein): 9 Avg length: 286,8 Avg pI: 9,30
Protein ID Length (AA) pI
5RDQF 390 9,53489
3pgDb 390 9,57376
8tqtK 389 9,39538
A0A0A8WIP6 271 8,95667
A0A2R2ZGL3 271 8,95661
A0A2R2ZH38 271 8,95661
A0A8S5RG13 189 9,65648
A0A8S5TWM7 225 9,23827
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_30607
6ndmR
 8 37,4% 270 1.631E-47
2 phalp2_11988
35NoL
 2 37,5% 245 1.130E-39
3 phalp2_21446
82r2O
 3 32,5% 249 2.670E-25
4 phalp2_263
6tFdA
 76 26,8% 380 6.419E-16
5 phalp2_11834
8nufL
 33 29,7% 252 2.666E-14
6 phalp2_4252
7Y66x
 61 26,2% 274 1.479E-13

Domains

Domains [InterPro]
Ami3
Unannotated
PG_1
Representative sequence (used for alignment): 5RDQF (390 AA)
Member sequence: A0A8S5N5R1 (185 AA)
1 390 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctnFo11
[NCBI] 		2826454 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015066 [NCBI]
CDS location
range 31961 -> 32518
strand +
CDS
ATGGTGAATAATATGAAGATCAATGTACATGCCGGGCATAACCCGGATGGAAAGATCGCTTGCGGAGCAGTAGGACTGATCAAGGAGTCCACAGAGGCACGCAAGGTCAAAAAAGAAGTGATCCGGCTTCTTAAAAAGAAAGGGCACAAGGCGTATGACTGCACCTGCACCAATGGGACAAGCCAGGCGGATGTCCTGAAGCGAATCGTCACAAAATGTAATAAGCATAAGGTGGATCTGGATGTTTCCATCCATTTCAATGCCGGAGCTGGCGACAAGAAAGGCAACGGCAAGACGACTGGAACGGAAGTGTATGTGTACAGTTCCACCAGCGCAGCGAAGCCGGCGGCAGAACGTGTCGTTAAAGAGATCGTGGCTCTTGGATTTAAAAACCGCGGTGTTAAGATCAGAACGGATCTGTATGTGCTACACAGAACCAATTCTCCGGCCATGCTGATCGAGTGCTGCTTCGTGGATGATAAGGACGATGTGGAACTGTATGATTACAAGAAGATGGCGGCAGCTATTGTTGCAGGAATCCTTGGATTGAAAGCATAG

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5RDQF) rather than this protein.
PDB ID
5RDQF
Method AlphaFoldv2
Resolution 86.11
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50