Protein

Protein accession
A0A8S5N3N9 [UniProt]
Representative
61rpn
Source
UniProt (cluster: phalp2_2528)
Protein name
Muramidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTQEQKKFIERVGALAAADMQKSGVLASLTIAQAILESGWGKSGLTVKGNALFGIKAGTSWTGAVYSGKTQECYDGVTFTTVTGLFRAYGSWAESVADHSDLLSCNTRYKAVIGERDYKTACRAIAAAGYATDPKYADKLVQIIETYALTAYDGAGSAAKPGGSNTAVGTTSPADAKGAGKMKASEFINKLQNIVDNYKTLYVMGCFGAPLTGANVSRYCTNHRYNKQAARTAMIRAAADKNPPVYGFDCVCLIKGVLWGWSGNAAKPYGGAAYASNGVPDLGADTMITKCSGVSADFSGIVPGEAVWLPGHIGVYIGGGKVIECSPAFKNCVQVTACLNIGAISGMNGRKWTKHGKLPYITYDTAGGAQDGAGSTTKPSGTTTTPATLAFAVGDVVRFTGNTHYTNAAAASGAACKPGTAKVTALAKGAKHPYHLIKQPGGGSTVYGWVNAADVQAVGSGTTAPKMRVGAKVKYSGPLYRDSNGGGQGKTVNGTYTVKYYYPARKCGVHIDGLGWVPESGCTVIG
Physico‐chemical
properties
protein length:526 AA
molecular weight:54426,1 Da
isoelectric point:9,28
hydropathy:-0,11
Representative Protein Details
Accession
61rpn
Protein name
61rpn
Sequence length
551 AA
Molecular weight
57172,18160 Da
Isoelectric point
8,77694
Sequence
MTQEQKAFIERVGALAAADMQKSGVLASLTIAQAILESGWGKSGLTVKANALFGIKAGTSWKGRVYSAKTQECYDGVNFTTVTALFRAYDSWEESVADHSALLTGAARYKAVIGERDYKTACRAIKAAGYATDPQYADKLIRLIESYGLTAYDGAGQAGAGGGSNTTAGAGNPADAKGDGKMKASEFIEKLQDIVDNYKTLYVMGCFGAPLTGGNVSRYCTNHSYNKQAARTAMIKAAANKNPPVYGFDCVCLIKGVLWGWCGDASKTYGGASYASGGVPDIGADTMITKCSGLSTDFSKIVPGEAVWLKGHIGVYIGGGKVIECSPAFKNCVQVTACLNIGAISGLNGRRWTKHGKLPYITYDTAETATGGAGTATKPGGASNTSGGLAFAVGDVVQFTGNVHYTNANAASGKACKPGKAKVTMISKGAKHPYHLVKESGGGSTVYGWVNAADVQSEADAAIEKLAGLGVINSPDYWKNAVAAGTVQYLDLLFISAAEHITKAGPRCATVQAGVDALVKAGAINSPDYWLQNYGKLQSLDLLLCALGGAV
Other Proteins in cluster: phalp2_2528
Total (incl. this protein): 217 Avg length: 524,1 Avg pI: 9,26
Protein ID Length (AA) pI
61rpn 551 8,77694
11GYj 564 8,47928
13Azx 526 9,28275
13E4K 530 9,33846
13qSW 488 9,55874
1FDvG 505 8,93443
1jEYp 518 8,87306
1oa0V 526 9,30622
2m2a7 526 9,34535
3B61P 525 9,28275
3IdzB 526 9,34535
3bV1a 423 9,27328
3jIEl 526 9,37791
3jWIs 526 9,28275
3lDHO 526 9,28282
3lcHH 526 9,37443
3m0mP 523 9,35760
3p2Hd 526 9,28275
3p7Kd 526 9,28275
3pRZ0 551 8,99116
3pf3N 526 9,40698
3qIZo 526 9,28282
3qWoy 526 9,34542
3qy43 463 9,51149
3rg2W 526 9,40698
3sjHT 526 9,24665
3smKM 503 8,68629
3t4AX 526 9,31183
3tHeL 414 8,87647
3tkSn 526 9,38081
3tosB 526 9,31183
3tzj4 526 9,40698
3uYMu 526 9,30629
3uf7O 526 9,34084
3uhsR 526 9,37443
3uras 526 9,35135
3vF1C 526 9,34090
3wSaQ 526 9,34090
3wqaK 526 9,34090
3wqvB 551 8,98227
3wrRV 526 9,28269
3xMNM 526 9,28282
3xr3P 526 9,40698
3ylP1 442 9,16239
4m17V 514 8,73490
4xCqH 429 8,53511
4xDC1 543 9,21822
4z1PA 551 8,71111
5JXNM 532 9,23286
5KoiU 526 9,24672
5LbWe 526 9,28275
5LylM 526 9,28275
5Mpr9 526 9,28275
5Mxxr 488 9,88276
5N2FQ 526 9,37791
5NFvx 526 9,28275
5NJiA 538 9,19946
5O4uJ 526 9,34090
5O5Dn 526 9,34535
5OQgD 526 9,28275
5P1hC 551 8,86165
5P6sw 526 9,28282
5PbUg 526 9,37443
5Q2Vt 526 9,28275
5QBu2 500 9,57151
5QNV7 526 9,35141
5Qu1x 526 9,40711
5RGgi 551 9,08200
5RNBu 526 9,24665
5RgaU 526 9,28275
5Ry6f 526 9,28275
5SHh3 526 9,28282
5SPSB 526 9,28275
5SnTN 526 9,37462
5TEKp 526 9,24672
5TUfK 479 9,84137
5TWvw 526 9,34535
5U02y 526 9,34090
5UTMl 526 9,30629
5VAsY 526 9,40698
5VOp2 551 9,08200
5VvhZ 526 9,31183
5WlZX 526 9,24665
5XMuO 526 9,24665
5XN5t 526 9,28275
5XVoQ 526 9,31770
5XZYb 526 9,31770
5XjvP 526 9,31183
5XkB4 526 9,31770
5Y76Z 551 8,99116
5YSuV 526 9,34090
5Z6lX 526 9,20926
5ZKrR 526 9,31770
5ZW5V 526 9,28275
607OP 539 9,36186
60icn 526 9,31763
612pe 526 9,37443
6166f 551 8,71453
61UWN 551 8,91387
61en8 526 9,40698
62FFZ 526 9,37443
62Zlz 526 9,43206
63hwn 526 9,28275
646Xa 551 8,77694
64MRw 399 9,07059
64ZAc 526 9,24665
655v4 526 9,31183
65DFP 526 9,27721
65FZK 526 9,24672
65LXv 539 9,41885
65ZcV 526 9,34090
65gLa 526 9,37185
65iWu 526 9,37449
65qmL 526 9,24672
65wxp 526 9,28275
661Vx 526 9,38075
66BcB 527 9,34542
67PjT 539 9,37153
67fLp 526 9,34090
68DJZ 526 9,31763
68IM7 526 9,24665
68S0c 526 9,28275
68qi2 526 9,30029
69oSh 526 9,31763
69ovj 526 9,31763
6aUDY 526 9,35760
6bDJ0 548 8,88266
6bEz0 526 9,34535
6cDJL 526 9,40698
6cHiu 551 9,24021
6cJA4 526 9,31183
6cnmZ 526 9,21455
6cqgh 526 9,24124
6djZU 526 9,40692
6e361 526 9,28269
6eYg5 526 9,28275
6efJe 551 9,03571
6ekkE 526 9,24665
6eyX7 526 9,34090
6fOms 526 9,28275
6fVqI 526 9,26515
6famE 526 9,31770
6h8UM 526 9,31183
6hYiE 526 9,34542
6iIEt 526 9,31183
6iU4U 526 9,34535
6imqk 526 9,28275
6j4SC 526 9,25220
6je9W 526 9,37443
6jewl 526 9,31189
6jk3O 551 8,71453
6jme0 526 9,30035
6jqjM 526 9,43200
6kEbZ 526 9,31763
6kEtB 526 9,35141
6kIz9 526 9,28275
6l1aW 551 8,71453
6l28l 526 9,31770
6l2WO 526 9,34535
6m562 526 9,32356
6mAPk 526 9,28275
6mFSm 526 9,37443
6mIZT 526 9,28275
6meaN 526 9,31763
6mtOZ 526 9,38081
6n1nP 526 9,31183
6nFrA 526 9,28275
6nsdv 526 9,40698
6oaUM 526 9,43200
6oqxA 526 9,28282
6pw49 527 9,37443
6q969 526 9,28275
6qahP 526 9,25220
6rKG8 526 9,24665
6rjpF 526 9,37443
6s3sM 526 9,34535
6s56s 526 9,37443
6s6cJ 526 9,37443
6sVgr 526 9,28275
6sm8t 526 9,28856
6soLX 551 8,86165
6thNF 526 9,34542
6uID5 526 9,33491
6uRB6 526 9,34709
6unSP 526 9,31763
6vFUD 526 9,25220
6vNqs 526 9,31183
6vXOp 526 9,36824
6vbTp 526 9,40060
6vcYV 526 9,30035
6vloR 526 9,28856
6w2A9 526 9,31183
6wQ3B 526 9,40054
75Ur3 544 9,09663
7BBbq 500 9,57151
7P8TS 526 9,34529
7rTXZ 526 9,34090
7rTvW 526 9,28275
7xRiJ 500 9,48422
85a37 544 9,15362
87GyK 526 9,31183
88oJ9 482 9,29417
8kGXm 516 9,12648
8mJPs 551 8,77706
8oaRm 526 9,31763
8pC0S 526 9,37179
8pJ0U 526 9,31763
BKuK 526 9,28275
lCRi 516 8,25855
mWol 543 9,25690
ofls 543 9,30596
okwu 516 9,02939
osnh 437 9,43032
owb1 526 9,46372
pL9R 494 8,97808
pSnw 526 9,31222
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_7918
npku
 3 70,5% 380 1.699E-176
2 phalp2_25258
7XZmQ
 197 57,5% 379 1.877E-140
3 phalp2_35339
7rQza
 10 59,2% 375 2.822E-130
4 phalp2_530
ofnu
 2 36,5% 550 2.853E-95
5 phalp2_21214
19jI2
 2 39,7% 403 1.680E-74
6 phalp2_25915
5TtYr
 397 27,2% 393 3.620E-34

Domains

Domains [InterPro]
GLUCO
Unannotated
Unannotated
Representative sequence (used for alignment): 61rpn (551 AA)
Member sequence: A0A8S5N3N9 (526 AA)
1 551 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01832

Taxonomy

  Name Taxonomy ID Lineage
Phage Caudovirales sp. ct7Ux15
[NCBI] 		2826767 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015058 [NCBI]
CDS location
range 9236 -> 10816
strand +
CDS
ATGACACAGGAACAAAAGAAATTCATCGAGCGGGTGGGCGCACTTGCCGCGGCGGATATGCAGAAAAGCGGGGTCCTCGCGTCCCTGACGATAGCACAAGCAATCCTTGAAAGCGGCTGGGGCAAATCCGGCTTGACGGTCAAGGGAAACGCCCTGTTCGGCATCAAGGCCGGGACAAGCTGGACCGGGGCCGTTTACAGCGGCAAAACGCAAGAGTGCTACGACGGCGTGACCTTTACGACCGTGACGGGCCTTTTCCGGGCCTATGGCAGTTGGGCGGAAAGCGTCGCCGATCATTCCGACTTGCTTTCGTGCAATACCCGCTATAAAGCGGTCATCGGGGAGCGGGACTATAAAACCGCGTGCCGGGCAATCGCCGCGGCGGGATATGCGACCGACCCGAAATATGCGGACAAGCTGGTTCAAATCATCGAAACATACGCCCTGACCGCCTACGATGGCGCAGGAAGCGCCGCAAAGCCCGGCGGTTCAAATACCGCGGTGGGGACCACAAGCCCCGCAGACGCGAAAGGAGCAGGCAAAATGAAAGCGTCTGAATTTATCAACAAATTGCAAAACATTGTGGACAACTATAAAACGCTGTACGTCATGGGCTGTTTCGGTGCGCCCCTGACAGGCGCGAACGTGTCCCGCTATTGCACAAATCACAGGTACAACAAGCAGGCCGCGCGAACGGCGATGATTCGGGCGGCGGCGGATAAGAACCCGCCCGTCTACGGGTTCGACTGCGTATGCCTTATCAAAGGCGTTCTTTGGGGTTGGAGCGGAAACGCCGCGAAGCCATACGGCGGCGCGGCCTATGCTTCCAACGGCGTTCCCGATCTTGGGGCCGACACCATGATTACGAAGTGTTCCGGCGTGTCCGCTGATTTCAGCGGCATTGTTCCGGGTGAAGCTGTCTGGTTGCCCGGTCATATCGGCGTATACATCGGCGGCGGAAAGGTCATCGAATGTTCGCCCGCTTTCAAGAACTGCGTGCAGGTGACGGCGTGCCTGAACATTGGCGCTATTTCCGGCATGAACGGGCGCAAGTGGACGAAGCACGGGAAGTTGCCGTATATCACCTACGACACCGCAGGCGGCGCACAGGACGGCGCAGGAAGCACGACAAAGCCCAGCGGCACAACTACCACCCCGGCGACGCTTGCGTTCGCTGTGGGCGACGTGGTGCGCTTTACGGGCAACACCCATTACACCAACGCGGCGGCGGCAAGCGGCGCGGCCTGCAAGCCGGGAACGGCAAAGGTAACGGCGCTTGCAAAGGGCGCAAAGCACCCCTACCACCTTATCAAACAGCCCGGCGGCGGTTCTACCGTTTACGGCTGGGTCAATGCGGCGGACGTGCAGGCCGTCGGGAGCGGTACGACCGCGCCGAAAATGCGCGTCGGTGCAAAGGTGAAGTATTCCGGCCCGCTGTACCGTGACAGCAACGGCGGCGGACAGGGCAAGACCGTAAACGGAACGTATACGGTGAAGTATTACTATCCGGCCCGCAAGTGCGGCGTACACATCGACGGTTTGGGCTGGGTCCCTGAATCCGGCTGTACCGTCATTGGTTGA

Gene Ontology

Description Category Evidence (source)
GO:0004040 amidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (61rpn) rather than this protein.
PDB ID
61rpn
Method AlphaFoldv2
Resolution 85.74
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50