Protein

Protein accession
A0A8S5MZR9 [UniProt]
Representative
64Nde
Source
UniProt (cluster: phalp2_25923)
Protein name
Endodeoxyribonuclease I
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAQLKQDLIAEDEKAMNIIENNLRFGNMTKRSKTERIILHHAAAETCSVEDIHRWHRNNGWAGIGYHFLVRKDGSVYRGRPENMMGAHASGANYNSIGICFEGNYQHEQSMPAAQLNAGAELVANLKAKYGISKVIAHRDVCSTACPGQYFPFNAIASGAPAATPSQPAQIDARKAFVRQVQSRIGVIVDGIVGPKTRAALPVLSRRRNRRHPVVQVVQARLRALGYNLGTYGVDGVYGSDTKSAVIGYQRDHGLSDDGVIGRATWNSLLVG
Physico‐chemical
properties
protein length:272 AA
molecular weight:29690,4 Da
isoelectric point:9,66
hydropathy:-0,32
Representative Protein Details
Accession
64Nde
Protein name
64Nde
Sequence length
93 AA
Molecular weight
10720,90100 Da
Isoelectric point
7,01339
Sequence
MEIIETNLQFKDMSTRKATQRIILHHADAKNCSAEDIHRWHLNNGWSGAGYHFLVRKDGKIYRLRPEDKVGAHAYGSNNNSLGICFEGNYMEE
Other Proteins in cluster: phalp2_25923
Total (incl. this protein): 24 Avg length: 92,7 Avg pI: 8,73
Protein ID Length (AA) pI
64Nde 93 7,01339
1phRP 95 6,27283
2TMZA 92 9,98391
2Yv8m 97 9,92770
3xMzX 84 9,51568
5NEIT 79 7,96947
5Nvj5 101 9,00328
5POkr 86 7,95658
5QKhM 73 9,72772
5T92V 78 9,25091
5TsIr 92 9,42768
5YRwr 96 6,27607
69Vs4 71 9,25071
6YVbg 68 9,51639
6b8X8 102 9,00328
6buMD 88 9,57892
6kAJ8 79 9,25091
6nzYk 78 9,30100
6oaLT 78 9,25091
6tjdN 80 9,00270
6wLYD 65 8,89182
b4EF 79 6,63552
n81c 99 7,75542
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27898
ipdG
 164 44,6% 65 3.490E-19
2 phalp2_21606
2vySa
 303 38,1% 76 6.579E-19
3 phalp2_1258
vH5l
 5 44,0% 75 1.141E-17
4 phalp2_9904
2GCXD
 1 41,7% 67 4.054E-17
5 phalp2_10521
87KcW
 27 36,0% 61 1.441E-16
6 phalp2_4275
7YpR0
 5 42,4% 66 1.978E-16
7 phalp2_32271
7BWDU
 12 31,1% 90 1.033E-12
8 phalp2_7769
7csDs
 1 38,7% 62 2.675E-12
9 phalp2_37043
NDSw
 22 33,8% 71 7.404E-09
10 phalp2_3113
44LQI
 1 31,5% 76 1.017E-08

Domains

Domains [InterPro]
Ami2
Representative sequence (used for alignment): 64Nde (93 AA)
Member sequence: A0A8S5MZR9 (272 AA)
1 93 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctoMB99
[NCBI] 		2826459 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015023 [NCBI]
CDS location
range 32809 -> 33627
strand +
CDS
ATGGCGCAATTAAAGCAAGATTTAATAGCGGAGGATGAAAAAGCTATGAACATCATCGAAAACAACCTGAGATTCGGCAACATGACGAAGCGCTCGAAGACCGAACGTATCATCCTGCACCATGCCGCGGCGGAAACATGCAGCGTGGAGGATATTCACCGCTGGCACAGAAACAACGGCTGGGCCGGAATCGGATATCATTTTCTCGTTCGCAAGGATGGCAGCGTCTATCGCGGACGCCCCGAAAACATGATGGGTGCACACGCCAGCGGCGCAAACTACAACTCGATTGGTATTTGCTTTGAGGGCAACTATCAGCACGAGCAGTCCATGCCCGCCGCGCAGTTGAATGCTGGCGCTGAGCTCGTTGCGAACCTCAAGGCGAAGTACGGGATCAGCAAGGTAATCGCCCATCGAGACGTTTGCTCCACCGCTTGCCCCGGCCAGTATTTCCCCTTTAACGCCATTGCCAGCGGCGCTCCTGCCGCAACACCCTCTCAGCCCGCTCAGATTGACGCCAGAAAGGCTTTTGTGCGTCAGGTGCAGAGTCGCATCGGCGTGATTGTAGACGGCATTGTAGGCCCGAAAACGAGGGCTGCGCTGCCTGTTCTTTCCAGAAGACGCAATCGCCGACATCCCGTTGTTCAGGTTGTACAAGCGAGACTTCGTGCTTTGGGATACAATCTTGGAACGTATGGGGTCGACGGCGTGTATGGCTCCGACACGAAGAGTGCGGTTATAGGATATCAGCGCGACCATGGTCTGTCTGACGATGGCGTTATCGGGCGCGCGACTTGGAACTCGCTGCTCGTCGGTTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (64Nde) rather than this protein.
PDB ID
64Nde
Method AlphaFoldv2
Resolution 97.82
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50