Protein

Protein accession
A0A8S5MZL8 [UniProt]
Representative
65GA0
Source
UniProt (cluster: phalp2_20813)
Protein name
Putative peptidoglycan binding domain protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MVTRAQIISAAQEEIGYSRWADDEAGSKYGRWYAQATGSPSFGASGVPYCDMFVSYILAKAGINWVSAYVPGRENQARDRGVLINKWDVRPGDLVTFDWQGDGESDHIGIATSAPYGTKIDTIEGNTSWGYSGSQGNGGVVTNKQRDMDDVVWGIRVVDDNSAISTGGDIRDIQRILGAIQDNILGQDTEKRMCAVIKASNWGGREFPWGVAYTQSVIGTEPDGIWGDASEAAHDRVIESLQAALGVTVDGIWGPETWAAWERLARTAERP
Physico‐chemical
properties
protein length:271 AA
molecular weight:29425,1 Da
isoelectric point:4,59
hydropathy:-0,38
Representative Protein Details
Accession
65GA0
Protein name
65GA0
Sequence length
273 AA
Molecular weight
29115,48110 Da
Isoelectric point
4,42801
Sequence
VTTRQDILNTAAAEVGYSRWDDPEAGSKYGRWYAQYKGAYFGASGVPFCDMFVSWVLFQSGINWLSAYVPGREAEARQRGVLISKWDVQPGDLVTFDWQGDGESDHIGIARTAPYGNNIDTYEGNTSPGTGGSQGNGGYVAARTRDMDDVVYGIRVVDAAVGPSPATGPSDITGVQRALGAEPDNVLGPDTERRLYLVVAASNWAGTHFPEGVAATQAIIGTEPDGIWGDASEAAHDRVVESIQRALGVDDDGIWGPATQAAWESLASRAERP
Other Proteins in cluster: phalp2_20813
Total (incl. this protein): 344 Avg length: 273,2 Avg pI: 4,63
Protein ID Length (AA) pI
65GA0 273 4,42801
11ssh 272 4,77643
11uJv 272 4,42795
11uOG 272 4,76529
11ugM 276 4,42897
11w9T 279 4,24442
11wWx 281 4,25226
1HHdR 271 4,60529
1Iako 282 4,10425
1IarF 278 4,30887
1ce32 271 4,64991
1cskU 271 4,63843
1cwSX 282 4,22401
1cxle 272 4,81429
1hR0j 281 9,71489
1kJuD 273 5,05238
1mehj 293 4,41596
2aLGP 272 4,43915
2biUE 271 4,76489
2bkXv 272 4,42801
3VHWL 303 4,32121
3bWAe 295 9,25413
3c3zI 283 4,43767
3c4qS 272 4,84913
3c64y 279 4,21611
3c6Qd 278 4,42897
3c6Ws 271 4,52412
3c6X3 281 4,48894
3c6xV 272 4,87203
3c6yB 271 4,53640
3c8Cz 271 4,63843
3c8EH 272 4,68253
3cfgo 278 4,36753
3dV0E 303 4,33837
3ikuh 301 4,36651
3jIXn 282 4,12983
3lMdW 282 4,62484
5KF2z 278 4,34036
5KLju 276 4,40448
5KR0g 258 4,07572
5LIUA 274 4,61688
5LUdV 271 4,51690
5Liy9 271 4,63621
5MElZ 276 4,42897
5MeYu 278 4,35969
5Mfq1 220 4,76000
5MjE0 276 4,34519
5MjiP 272 4,46296
5MtFq 278 4,26681
5NEWc 281 4,12545
5NXsX 221 4,78899
5NqlX 281 4,34434
5OqUD 275 5,45748
5PRhT 279 4,25590
5Q7f5 281 4,17036
5QYuy 291 7,98146
5QuNu 279 4,36242
5R9jK 278 4,49025
5RBGK 271 4,74619
5RO2k 272 4,46149
5RXYF 321 7,60957
5RueR 272 4,87203
5RvFJ 242 4,36298
5SmoV 278 4,47848
5U6cs 272 4,80877
5UJZx 271 4,60307
5V6sI 278 4,42897
5VIAW 272 4,96445
5VNz8 272 4,95041
5W7PO 278 4,42488
5Y4Gu 272 4,53180
5Y9pY 275 5,66539
5ZDPR 284 4,34718
5ZYle 275 5,95482
5Zkhu 272 4,88482
5ZpUy 279 4,20895
5Zpdd 221 4,78899
60Zbb 278 4,34804
60ZwJ 279 4,22623
60bUl 221 4,80332
60qAy 272 4,46149
61GkK 271 4,42494
61dh0 251 4,18207
61eIP 271 4,57300
62WwJ 282 4,14387
63Ljy 242 4,59864
63lfc 278 4,53594
64XLt 276 4,37884
64rmi 277 4,33621
65NuC 278 4,32416
65yFo 242 4,23004
6735j 288 7,76207
676Sd 279 4,20878
67MyF 279 4,30467
67spY 276 4,42505
67u9q 272 4,92825
682D8 271 4,58244
68Dye 278 4,41766
68dWw 278 4,34519
68r8b 271 4,51219
69HQa 287 6,96735
69rG7 271 4,43631
69rGl 271 4,52685
69wEx 272 5,05449
6Z1EV 281 4,32570
6ZQNv 272 4,46546
6ZTNd 278 4,41545
6ZU2i 278 4,38885
6ZapO 278 4,37094
6Zdy1 276 4,42897
6ZpQV 272 4,74204
6ZpRM 271 4,74591
6adLH 271 4,49815
6aem6 271 4,55982
6b1Gr 228 4,10829
6bGVz 276 4,42505
6btVl 258 4,05003
6bzcr 275 5,82244
6bze9 272 4,79803
6c02l 271 4,61575
6c8n5 221 4,87152
6cMxw 271 4,53430
6cmEs 242 4,30899
6coqU 271 4,56436
6d0aW 234 4,23220
6dzme 276 4,37884
6f9gj 278 4,50787
6fQeB 283 4,25527
6ggbL 279 4,19542
6hIAZ 186 4,30791
6hrte 281 4,28852
6iVCn 281 4,30353
6icDf 279 4,19764
6iieZ 277 4,22492
6jfi9 271 4,64991
6k9AQ 278 4,40448
6kAjB 272 4,73670
6kAju 271 4,55209
6kbK9 271 4,49297
6m7Ik 242 4,30279
6mZMJ 282 4,54061
6oLl4 271 4,64689
6oTvi 221 4,82770
6oXme 278 4,35503
6p4GW 275 5,95482
6pBHm 279 4,30887
6pG5a 272 4,81900
6rf4k 271 4,60301
6rf5k 272 4,87311
6sg7x 271 4,59176
6sxGz 278 4,44023
6t8zC 278 4,38373
6tQ9T 278 4,37157
6tZ0G 271 4,60301
6teT3 271 4,57465
6uCKa 279 4,20651
6uDZI 313 4,23970
6uY81 279 4,22492
6uish 221 4,79780
6v5Ya 281 4,28460
6vL3e 278 4,30887
6vPre 277 4,26806
6wg1J 283 4,16314
700Rq 271 4,60301
700eY 276 4,37094
708ms 272 4,82713
70F4S 293 4,33036
70Hpn 271 4,45569
70T5w 271 4,54890
70Wxp 276 4,41766
70muV 271 4,63843
70se2 271 4,50508
70sf3 271 4,56715
70uIL 282 4,12983
70xjp 278 4,42897
70yPP 232 4,33428
7M9wa 272 4,74204
7MANu 293 4,34059
7MUZa 282 4,12983
7MZtv 271 4,76529
7Mczl 285 4,33383
7MgXL 271 4,67764
7MvGo 272 4,77643
7MxT9 272 4,76512
7N45V 271 4,63843
7N77a 271 4,63843
7N8kk 278 4,42897
7NKZT 284 4,42653
7NPz9 282 4,12568
7NVw7 278 4,37094
7NunN 282 4,12568
7ONeY 283 4,38328
7OUJE 283 4,39498
7OWp8 293 4,39720
7OYUC 271 4,62666
7OxVJ 272 5,04119
7UNHJ 272 4,46444
7UNHR 272 4,67094
7UNYJ 278 4,38328
7UNvT 272 4,79604
7UNxF 281 4,61779
7UOqy 272 4,74136
7YqGg 271 4,47956
7YyBZ 271 4,82639
7ZASU 272 4,43903
7ZzQo 271 4,59176
7iPXi 286 7,76724
7ogXc 278 4,43039
7qJ6I 292 8,48676
7qJqy 286 7,77281
7sxQe 296 9,55745
7ui2c 278 4,39834
83JnK 237 4,43233
84o7L 271 4,54669
84ouG 272 4,43761
84yQY 207 4,34889
853Z0 279 4,43039
88V9m 271 4,72448
8IImw 287 7,01270
8IImx 272 4,88369
8IImz 278 4,38885
8aUOx 271 4,63843
8b1p8 271 4,60301
8bE1x 272 4,43903
8cFNd 271 4,54362
8caFc 272 4,76967
8cal6 272 4,49110
8cc0z 282 4,12983
8ccgQ 272 4,43903
8h9sd 278 4,39351
8h9uA 282 4,13910
8hcxi 281 4,64564
8hhAK 284 4,59352
8hj7J 272 4,92177
8icom 271 4,52634
8kuea 272 4,43903
8l5ut 272 4,40379
8lHep 271 4,66565
8lpAM 272 4,76967
8lq55 271 4,53043
8lqJA 271 4,59483
8mKSV 272 4,46535
8mYmi 271 4,53271
8ncre 272 4,52941
8nf5C 271 4,46723
8oAkE 271 4,52122
8pLL3 234 4,34133
8pMkx 271 4,47956
8qUnQ 279 4,24442
8qVgX 281 4,27267
A2k5 272 4,91841
A5d7 293 4,39726
BDr8 272 4,49121
BPI0 272 4,79604
BVL7 293 4,38248
BuKI 271 4,45745
CUsk 249 4,73949
D8tO 271 4,68952
DDiJ 280 4,28750
DQI6 271 4,60301
DRcd 278 4,41766
DSxK 293 4,36134
DT1c 282 4,28835
DU4I 272 4,87164
DUmB 271 4,56715
DvjT 278 4,39601
Dxus 274 4,72647
EIR8 278 4,36207
F1GO 279 4,26425
F25q 282 4,11664
HD9N 278 4,36020
HDyx 279 4,19542
HHwm 324 7,70898
HIvJ 271 4,63843
HMhD 272 4,47689
Hkgc 279 4,24442
Hrbt 281 4,28460
Httc 272 4,43903
HuBW 293 4,38697
Hvpz 281 4,27267
Hz2j 279 4,19542
JUbv 278 4,33894
K5EL 282 4,18587
K9sW 276 4,42505
KD7a 278 4,42897
KDeo 278 4,32212
KIRI 271 4,67764
KKhJ 277 4,26511
KLob 271 4,60301
KQ7j 282 4,13119
KQzg 279 4,21350
Ka6M 278 4,35503
Kw9M 271 4,60301
MRdo 276 4,43705
N23E 293 4,42926
N4zA 272 4,85385
NNAE 239 4,76000
NaAk 278 4,27522
NeLR 282 4,15524
Nfbs 276 4,39834
Nkrt 282 4,11664
Nl2E 278 4,38328
Nzto 261 4,40072
O5Ul 278 4,41334
O7du 279 4,18013
OOgz 272 4,81537
OQv5 282 4,20503
OaTr 271 4,63843
OkON 271 4,60301
OoUu 271 4,60068
OsRg 272 4,88408
V0gb 271 4,53970
oBFW 271 4,55982
oBjO 272 4,60654
oCm9 271 4,62700
oFBB 272 4,43915
oGUP 278 4,41334
oHMt 278 4,46507
oLv1 281 4,29296
oSuF 272 4,43903
p69x 278 4,48166
pM9Y 271 4,63843
pMiw 262 4,66628
pOqA 282 4,11664
pP42 271 4,60301
pegq 272 4,68168
qbkC 228 4,98611
qfPu 272 4,79638
rkW6 217 5,21330
rkYj 271 4,48962
rl33 281 4,76444
roLz 279 4,24442
wMVh 272 4,47689
wMVn 271 4,60301
wX7h 208 4,54623
xAgd 278 4,23976
xApo 278 4,40101
ye7K 282 4,23203
ygh4 276 4,39834
ynRs 281 4,46092
yukL 279 4,21350
z6EX 279 4,22782
zgIh 271 4,60301
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_15543
8rE1J
 35 35,3% 277 2.334E-82
2 phalp2_2684
7236j
 6 50,8% 171 1.135E-72
3 phalp2_36057
6gvlc
 1 48,8% 180 2.620E-71
4 phalp2_552
ESm7
 27 47,9% 173 4.398E-67
5 phalp2_36689
5M39B
 515 37,6% 234 1.878E-62
6 phalp2_4061
1gHkc
 4 40,2% 216 1.878E-62
7 phalp2_22129
6wVUf
 53 30,8% 369 1.818E-56
8 phalp2_29611
88cwQ
 48 30,3% 303 4.397E-50
9 phalp2_5932
67zj5
 27 35,9% 206 7.016E-46
10 phalp2_1568
7XJtL
 188 31,1% 273 3.578E-43

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 65GA0 (273 AA)
Member sequence: A0A8S5MZL8 (271 AA)
1 273 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctJYR5
[NCBI] 		2826551 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015028 [NCBI]
CDS location
range 14937 -> 15752
strand +
CDS
ATGGTCACCCGAGCACAAATCATCTCCGCCGCCCAGGAGGAAATCGGCTACAGCCGCTGGGCAGACGACGAAGCGGGCTCCAAGTACGGACGCTGGTACGCCCAAGCAACCGGCTCCCCCAGTTTCGGTGCCAGCGGCGTCCCCTACTGCGATATGTTCGTGTCCTACATTCTCGCCAAGGCAGGCATTAACTGGGTAAGCGCCTACGTCCCCGGCCGCGAGAACCAGGCCCGCGATCGTGGCGTCCTCATTAACAAATGGGACGTGCGCCCCGGCGACCTAGTCACCTTCGACTGGCAGGGAGACGGAGAGTCCGACCATATCGGAATCGCTACCAGCGCACCCTACGGGACCAAGATTGACACCATTGAAGGAAACACTTCATGGGGTTATTCCGGGTCACAGGGTAATGGTGGCGTCGTTACCAATAAGCAGCGCGATATGGATGACGTTGTCTGGGGCATTCGCGTAGTCGACGACAACTCCGCCATTTCCACTGGCGGCGATATCCGAGACATTCAGCGAATCCTCGGCGCCATACAGGACAATATCCTTGGGCAGGACACCGAGAAGCGAATGTGCGCCGTCATTAAGGCCAGCAACTGGGGCGGACGCGAATTCCCCTGGGGCGTCGCCTACACTCAGAGTGTAATCGGCACAGAGCCCGACGGAATCTGGGGCGACGCCAGCGAAGCCGCCCACGACCGCGTCATCGAATCCCTACAGGCCGCACTCGGCGTCACCGTCGACGGCATATGGGGCCCCGAAACCTGGGCCGCCTGGGAGCGACTAGCCCGCACCGCAGAACGCCCATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (65GA0) rather than this protein.
PDB ID
65GA0
Method AlphaFoldv2
Resolution 90.85
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50