Protein

Protein accession
A0A8S5MUL8 [UniProt]
Representative
D7gk
Source
UniProt (cluster: phalp2_23707)
Protein name
Peptidoglycan-recognition protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MFRQITMDELKALALDAYGKIEKAYLHWTGVKDGKHFKDYHINIDRAGTMWTDMEALTDYKEHTYMRNSNAVGIAIEACWDAVSENNLGSEPPTKEQLATMTQIMAVLTINAGVPLDIQHQMTHAEAADNKDGLDLYYLDPTGYPNNTYGPDSNVDRWDLLVCHEGDERWSGGDWLRGTARWWGAQWGSTI
Physico‐chemical
properties
protein length:191 AA
molecular weight:21657,9 Da
isoelectric point:4,78
hydropathy:-0,57
Representative Protein Details
Accession
D7gk
Protein name
D7gk
Sequence length
132 AA
Molecular weight
14660,75370 Da
Isoelectric point
5,18982
Sequence
MFRQITMDELQALALKAYGQIEKAYYHWTGVKGGKHFTDYHINIARDGTMLTDMEALTDYKEHTYMRNSNAVGIAIEACWDAVSENNLGSEPPTTAQLTTMAQIMAVLAINIVIFNLIPIPALDGGKILINL
Other Proteins in cluster: phalp2_23707
Total (incl. this protein): 6 Avg length: 153,8 Avg pI: 4,88
Protein ID Length (AA) pI
D7gk 132 5,18982
1kHl0 113 4,89250
qhy8 105 5,18982
A0A8S5UEQ0 191 4,59261
A0A8S5UWK4 191 4,62257
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_31144
3u0Gd
 7 46,9% 81 2.448E-18

Domains

Domains [InterPro]
Peptidase family M50
Representative sequence (used for alignment): D7gk (132 AA)
Member sequence: A0A8S5MUL8 (191 AA)
1 132 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF02163

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctv1i11
[NCBI] 		2826709 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014992 [NCBI]
CDS location
range 38841 -> 39416
strand +
CDS
ATGTTTAGACAAATTACAATGGACGAGTTGAAGGCCTTAGCACTAGATGCATACGGCAAAATTGAAAAGGCATACCTGCATTGGACTGGCGTCAAGGACGGTAAGCACTTCAAGGATTACCATATCAACATCGACCGAGCTGGCACGATGTGGACCGATATGGAAGCATTAACCGATTATAAGGAACACACTTATATGCGGAACAGTAACGCTGTAGGCATTGCTATTGAGGCGTGTTGGGATGCAGTCAGTGAAAATAATCTTGGTAGTGAGCCACCAACAAAAGAACAGTTGGCCACTATGACACAAATTATGGCAGTGCTCACTATTAACGCGGGTGTACCACTTGACATACAACATCAAATGACACACGCCGAGGCGGCCGATAATAAGGACGGCCTAGACCTCTATTATTTAGATCCGACGGGATACCCTAATAATACTTACGGCCCGGACTCCAACGTTGACCGATGGGACCTCCTAGTGTGCCATGAAGGTGACGAACGATGGAGTGGTGGTGACTGGTTACGTGGCACCGCTCGATGGTGGGGCGCTCAGTGGGGTAGTACGATTTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (D7gk) rather than this protein.
PDB ID
D7gk
Method AlphaFoldv2
Resolution 92.34
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50