Protein

Protein accession
A0A8S5MP77 [UniProt]
Representative
5TGNK
Source
UniProt (cluster: phalp2_4896)
Protein name
CHAP domain protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 96% (predicted by ML model)
Protein sequence
MYKPRLKAPAPNNVLWTKKNPFFRAGYGLPNCTAYVWGRWYELIGKAPKLSLGNAGDWYKNIKDGYERGDTPRLGAVICWSKVGGEAQGKGHVAIVEKINPDGSIVIGESGYKKFRFRTMTLKPPYTYFTGYKLQGFIYCPAVKERTYDVLSTLNIRAKPSLTGKVLDKLKKGESVTGIPSGTWLKTEKGYVRIRGIKEYLREI
Physico‐chemical
properties
protein length:204 AA
molecular weight:23008,5 Da
isoelectric point:9,87
hydropathy:-0,46
Representative Protein Details
Accession
5TGNK
Protein name
5TGNK
Sequence length
204 AA
Molecular weight
22894,28160 Da
Isoelectric point
9,92293
Sequence
MYKPRLKAPAPNNVLWTRKNPFHSAGYGLPNCTAYAWGRWYEIIGKAPKLSLGNAGNWYKNIKDGYDRGDTPRLGAVICWSKVGGEAQGKGHVAIVEDIKSDGSIVIGESGYKKFRFRTMTLKPPYTYFTGYKLQGFIYCPKVAEKTYRVLSTVNIRQKASLTAPKAGKLKKGEYVTGIPQGTWLKTDKGYARIKGIREYIKEI
Other Proteins in cluster: phalp2_4896
Total (incl. this protein): 9 Avg length: 202,4 Avg pI: 8,83
Protein ID Length (AA) pI
5TGNK 204 9,92293
5PuMH 146 10,01299
64gV6 204 9,83486
67QY7 202 9,89939
6gRoj 240 5,22637
6oNhW 204 9,92293
6seK3 204 9,87412
6tjq8 214 4,94092
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_18807
1gBg7
 77 48,9% 149 7.137E-47
2 phalp2_11680
1Nyjf
 74 49,6% 149 5.232E-41
3 phalp2_40337
3iVXO
 43 47,0% 170 5.232E-41
4 phalp2_10722
3dYCr
 65 43,8% 171 1.084E-38
5 phalp2_12720
41oqI
 16 38,8% 211 1.439E-32
6 phalp2_3062
21xLs
 8 38,3% 146 4.493E-31
7 phalp2_36602
21saM
 3 33,8% 201 2.145E-30
8 phalp2_4546
3WKbr
 13 35,2% 156 3.029E-25
9 phalp2_17558
5WoZV
 75 33,9% 168 1.437E-24
10 phalp2_25206
24Le0
 10 32,4% 197 3.656E-24

Domains

Domains [InterPro]
CHAP
Unannotated
Representative sequence (used for alignment): 5TGNK (204 AA)
Member sequence: A0A8S5MP77 (204 AA)
1 204 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctoqT5
[NCBI] 		2826577 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014952 [NCBI]
CDS location
range 19934 -> 20548
strand -
CDS
ATGTATAAACCAAGATTGAAAGCCCCAGCGCCGAATAATGTGCTGTGGACGAAAAAAAACCCGTTTTTTAGAGCGGGGTACGGGCTGCCGAACTGTACGGCTTATGTATGGGGGCGGTGGTATGAGCTAATAGGAAAAGCACCTAAATTGTCGCTTGGCAATGCCGGTGACTGGTATAAGAACATCAAAGACGGCTACGAGCGAGGCGACACGCCAAGACTTGGAGCCGTTATTTGTTGGTCGAAAGTCGGCGGCGAAGCACAGGGCAAAGGCCATGTTGCCATTGTCGAAAAAATCAATCCCGACGGCTCTATTGTCATAGGAGAGAGCGGATATAAGAAATTCCGCTTCCGTACAATGACCTTAAAACCTCCGTATACCTATTTCACAGGTTATAAGCTGCAAGGATTTATTTATTGTCCTGCCGTGAAAGAGCGTACTTATGATGTTCTTTCGACGCTCAATATCAGAGCAAAGCCGTCTCTTACAGGGAAAGTGCTTGATAAACTGAAAAAGGGAGAATCTGTGACAGGTATTCCGTCCGGTACATGGCTGAAAACCGAAAAGGGATATGTACGAATTAGAGGAATTAAAGAATATCTTAGGGAGATTTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5TGNK) rather than this protein.
PDB ID
5TGNK
Method AlphaFoldv2
Resolution 96.75
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50