Protein

Protein accession
A0A8S5MNP1 [UniProt]
Representative
6XoIV
Source
UniProt (cluster: phalp2_36180)
Protein name
Cell wall hydrolase autolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRIGLNAGHTLNGPGSGAVGVLIESVETRRIVQAITPMLQAAGCEVVDCTVDKAASQSAYLKEVVKLANRQDLDWFISFHLNNDAAKKGKGVEAYTYQGRQYPDAVEVCELIAALGLKNRGVKEGSGLYVIKKTKAKSILFEICFVNEPDASTYQRQFDEICKAIVYGLADYVGAVTKPEPPSALPEKKQYVRVKCDNLSIRSKPSWADDAVCGTVRKNEVFTISEGPITVGNGKMYRLKSGVYITAAEEYVETYEK
Physico‐chemical
properties
protein length:257 AA
molecular weight:28128,9 Da
isoelectric point:8,05
hydropathy:-0,21
Representative Protein Details
Accession
6XoIV
Protein name
6XoIV
Sequence length
397 AA
Molecular weight
44113,97490 Da
Isoelectric point
4,93393
Sequence
MTIGINCGHTVSGAGYGAVGIIKESEHARLVGYALMEKLRAAGVKVVDCTIDEANTQGEYLAAAVALANREDLDWFISIHFNASLTHDGQGVEVYTYEGKQYQDALDVCNNIAAHGFKNRGVKAGTGLYVIKNTKAKAMLIEVCFCDNQADVDLYNSIGGADTIAQAIFNGIYDYAVTPEPVPEENHDMAFEEFAEYVGEIARQDWIDRKIMLPSVVVAQAIKESARGTSELARNANALFGIKKNGWTGKTYRKAATEQRSDGSYYTVDNTEWRSYGSWKESILDHNTYIAERSTDSGKTLRYGPLIGCEEYVLACQYLQDLGYATSLTYAESLINDYIEKYDLTRFDVVEDELAPDGKLWVVQLGAYKSRNNAERFIKRLEGMGIISLLKQYNIEQ
Other Proteins in cluster: phalp2_36180
Total (incl. this protein): 23 Avg length: 388,1 Avg pI: 5,79
Protein ID Length (AA) pI
6XoIV 397 4,93393
13a8w 401 5,21307
1k48P 401 5,58184
1oeNb 398 6,18229
2sLP 405 5,91736
3nABD 399 5,40541
3nYiE 399 5,14623
3qh6Z 405 5,91736
3w0Dt 405 5,04676
5j1o1 395 6,30506
6WWUv 428 5,09166
7X1rL 294 5,59144
7e98U 401 5,51898
7nG9z 401 5,68000
7pdW3 402 5,50437
89xjq 408 5,06381
8fOdJ 354 7,85388
n4VM 397 5,66011
n6HB 397 5,66568
nK9b 397 5,58320
ocr4 397 6,20434
ono3 389 6,02814
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_20819
6dUOP
 6 31,8% 320 1.071E-47
2 phalp2_10294
1gJBd
 19 30,0% 360 2.690E-47
3 phalp2_18634
8Scy
 22 32,5% 301 7.729E-44

Domains

Domains [InterPro]
Ami3
GLUCO
Representative sequence (used for alignment): 6XoIV (397 AA)
Member sequence: A0A8S5MNP1 (257 AA)
1 397 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF01832

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctJfU3
[NCBI] 		2826638 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014944 [NCBI]
CDS location
range 21365 -> 22138
strand +
CDS
ATGAGAATCGGATTAAACGCAGGACACACGTTAAACGGACCGGGAAGCGGAGCAGTTGGGGTACTGATTGAAAGCGTTGAGACACGCCGCATCGTACAGGCGATCACACCGATGCTTCAGGCGGCAGGCTGCGAGGTGGTCGATTGTACGGTAGACAAGGCGGCATCCCAGAGTGCATACCTGAAGGAAGTTGTAAAACTGGCGAACAGGCAGGACTTAGACTGGTTTATCAGCTTCCATTTGAACAATGATGCTGCCAAAAAGGGAAAAGGCGTGGAAGCATATACATACCAGGGAAGACAGTACCCTGACGCTGTGGAGGTTTGTGAGCTGATCGCAGCGCTTGGCTTAAAGAACCGCGGCGTAAAAGAGGGAAGCGGTTTATACGTTATCAAAAAGACAAAAGCTAAGTCAATTTTATTTGAGATTTGCTTTGTCAACGAGCCGGATGCATCCACCTACCAGAGACAATTTGACGAAATCTGCAAGGCAATCGTGTATGGCTTGGCGGATTATGTTGGTGCAGTTACAAAGCCGGAGCCGCCGAGTGCACTGCCAGAGAAAAAGCAGTATGTGCGCGTGAAGTGCGACAATCTGTCCATAAGAAGCAAGCCAAGCTGGGCGGATGACGCCGTATGCGGAACGGTGAGAAAGAACGAGGTGTTCACGATTAGTGAAGGACCAATCACCGTTGGCAACGGAAAGATGTACAGGCTTAAATCAGGTGTGTACATCACCGCTGCGGAGGAATATGTGGAAACATATGAGAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6XoIV) rather than this protein.
PDB ID
6XoIV
Method AlphaFoldv2
Resolution 93.66
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50