Protein

Protein accession
A0A8S5MEP9 [UniProt]
Representative
7ZZsG
Source
UniProt (cluster: phalp2_37317)
Protein name
Peptidoglycan-recognition protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTNKLYRCIVHWSAGTGKANATDKSHYHFLVQNDGSVIKGNYIPEDNANCNDGRYAAHTGGGNTGSIGISLCGMAGYQQGKPQSTKYPLTAIQCEAAWKKIAELCKAYNIPVTPETVMTHYEFGIKHPKTSSAGKIDIVYLPSQPKLKKEEIGNFIRNKVKWYYNNI
Physico‐chemical
properties
protein length:167 AA
molecular weight:18503,9 Da
isoelectric point:9,21
hydropathy:-0,54
Representative Protein Details
Accession
7ZZsG
Protein name
7ZZsG
Sequence length
344 AA
Molecular weight
36784,53330 Da
Isoelectric point
8,45582
Sequence
MTVNQQGKLVRVIAHWTGGGGRASDLDRKHYHRMVEYDGSIIFGNETPEDNIVTSDGDYAAHTLNLNTGSIGVAVCGMAGAKEQPFEAGDAPITERQFRAFAILIADLCRTYAIPVTASTVLTHAEVQHTLGVKQKGKWDIARLPFRPELVGPRAVGDYLRDLVREAYGEPAPTMDLPPLRHGDRGPLVKDWQGQLASMGYFVGKQDGIFGVRTRAGTLAFQADNGLPTDGVVGPRTRGKMATAMPPPKRDVSTDDLRKRGSETIKAADKIDLAAGAAAVTTALPAVKDAVEQATGILPTLTALVRDHWPALVVIALLAGAVVLSRRIRSDRVAAAVNGEDLSK
Other Proteins in cluster: phalp2_37317
Total (incl. this protein): 35 Avg length: 342,6 Avg pI: 6,87
Protein ID Length (AA) pI
7ZZsG 344 8,45582
13j8A 343 7,19868
17cXP 343 6,45909
1suMh 346 5,84927
2I265 351 8,33120
2TYVz 351 6,64876
3PxX 356 6,00341
3eYIE 365 6,80126
3iGOD 346 6,08810
3mPXd 346 6,08589
48lwj 345 7,21215
4Khks 351 5,40331
4UmUO 347 7,94104
4hcib 329 9,47139
4jVFO 382 8,79080
4uIJC 351 6,76000
5I863 321 5,63277
5sJ0f 343 7,14633
6MZQu 346 5,40336
71mrQ 346 6,20900
7Bdlx 335 7,10194
7TaZp 346 6,08810
7cuRi 346 6,00637
7lzB 347 6,16671
7orge 334 6,00279
7rT7f 351 9,04274
7sp4I 352 8,28917
80Xod 344 5,26473
8AFN2 353 6,25953
8dNXZ 370 7,07028
8erEN 346 6,08737
Yub2 346 6,25760
xEYz 350 6,51963
xLAl 353 7,16918
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_19974
6PE0f
 7 44,5% 249 2.216E-87
2 phalp2_9404
8Fz4V
 29 46,8% 220 4.786E-77
3 phalp2_22282
7wBZw
 14 44,4% 243 2.490E-74
4 phalp2_25618
48uUY
 31 28,5% 235 1.761E-24
5 phalp2_2920
NQqI
 114 28,5% 235 9.244E-17
6 phalp2_19675
4Bope
 30 26,0% 219 2.338E-14
7 phalp2_12351
98nO
 35 27,2% 261 5.574E-14
8 phalp2_15742
3xGp4
 1 24,5% 244 2.330E-10

Domains

Domains [InterPro]
Ami2
PG_1
Unannotated
Representative sequence (used for alignment): 7ZZsG (344 AA)
Member sequence: A0A8S5MEP9 (167 AA)
1 344 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctYh54
[NCBI] 		2826379 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014884 [NCBI]
CDS location
range 44082 -> 44585
strand -
CDS
ATGACAAATAAATTATATAGGTGCATCGTCCATTGGTCAGCTGGGACAGGAAAAGCAAATGCAACAGATAAATCTCATTATCATTTTCTTGTTCAGAATGATGGAAGTGTTATAAAAGGCAATTACATACCCGAAGACAATGCTAATTGCAATGATGGTCGTTATGCAGCACATACAGGCGGTGGAAACACTGGTTCAATAGGAATCTCTTTATGTGGAATGGCTGGGTATCAACAAGGAAAACCACAAAGCACCAAATATCCGCTCACTGCTATCCAATGTGAAGCAGCATGGAAAAAGATTGCAGAATTATGCAAAGCATACAACATTCCAGTAACCCCAGAAACGGTAATGACGCATTATGAGTTTGGGATTAAACATCCTAAAACTTCAAGTGCAGGTAAGATTGATATAGTGTATCTTCCTTCTCAACCAAAGTTGAAAAAGGAAGAAATAGGAAACTTTATACGCAATAAAGTTAAATGGTATTACAATAATATTTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7ZZsG) rather than this protein.
PDB ID
7ZZsG
Method AlphaFoldv2
Resolution 87.26
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50