Protein

Protein accession
A0A8S5MEJ9 [UniProt]
Representative
70eSG
Source
UniProt (cluster: phalp2_13805)
Protein name
Lysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MFTLTQAINYVRNLADNNIGVNFDGWYGWQCWDLVAKVMYEATGKVVNGNAINLPESAEAQGLNVIQEGPGVIAKAGDIFVMDVPGSPYGHTGVVIEDSDGYTLKTIEQNVDGNWDYLENGGPARYRTRSYANMVAFIRPDYATDSENVQRPSGWLEDEKGWWYRNDDGSYPKSKWEKINGSYFRFDDNGYALENTWYQDDEGLWYWLKPGGFMAVGWQLINNKWYFFNNVGEMQTGWIQYFDKWYYCTNENGDMVSKEVRKIGDKFYYFNDKGEMLERAAVYVDENGVIHFEE
Physico‐chemical
properties
protein length:294 AA
molecular weight:34005,2 Da
isoelectric point:4,48
hydropathy:-0,62
Representative Protein Details
Accession
70eSG
Protein name
70eSG
Sequence length
306 AA
Molecular weight
35058,73930 Da
Isoelectric point
4,71306
Sequence
MADNITVIKRRIFMFTLTHAINYVRNLADNNIGVNFDGWYGWQCWDLVAKVMYEATGKVVNGNAIDLLDSAAAQGIKVIQEGPGVIAKAGDIFVMDVPGSPYGHTGVVIEDSDGNTLKTIEQNVDGNSDYLEVGGPARYRTRSYTNMVGFIRPDYAADSEIVQQPSGWVEDEKGWWYRNVDGSYPQSDWVKINGSWFRFDKDGYALENSWYQDEQGRYFWLKGGGYMAIGWLKIGDFWYFFENNGEMRTGWIPYFDKWYYCIPENGAMVSKEVRKIDGKYYYFNSNGEMLERAAVYVDENGAMHFE
Other Proteins in cluster: phalp2_13805
Total (incl. this protein): 253 Avg length: 288,5 Avg pI: 4,66
Protein ID Length (AA) pI
70eSG 306 4,71306
11utt 292 4,49752
1HHcR 293 4,71544
1HKmP 288 4,65070
1Ianl 293 4,59330
1clog 294 4,69049
1kJ7L 288 4,36935
3Idb8 260 4,51742
3c6mp 296 4,66679
3kV8p 288 4,50377
5JTyI 292 4,54601
5Kb4V 281 5,28196
5KrLI 288 4,61569
5LMHa 282 5,14185
5Q4oy 294 4,51025
5Srm4 288 4,69504
5Vivo 281 5,01811
5WLa3 288 4,53828
5Y4hx 288 4,45245
5YN2u 292 4,59455
5Yc7c 294 4,63087
5YqOF 293 4,38748
602RI 292 4,57329
609Uk 288 4,59028
60YSY 282 5,24916
61kXT 288 4,64684
61te6 281 4,94985
620sG 299 6,17558
62cSQ 294 4,56471
62cgg 240 4,11079
63czi 288 4,58483
63wcB 294 4,62149
65ftM 293 4,91540
669pW 289 4,62694
6775K 292 4,54601
68Drb 281 5,01805
68Ndh 295 4,81019
68NgP 287 4,79900
693kY 288 4,64371
69oM0 297 4,62211
6YHJy 297 4,68628
6YKpk 288 4,63308
6Ybqv 286 4,26693
6Yg3X 288 4,63632
6YgN2 294 4,57988
6ZBXe 288 4,63530
6ZNX3 290 4,49371
6ZO6L 294 4,57988
6ZUmS 292 4,93251
6ZiST 297 4,57892
6Zj1A 294 4,54441
6ZjLx 288 4,53407
6ZtO8 267 4,50656
6ZzV8 288 4,54953
6a0MX 288 4,71391
6aHTw 252 4,90347
6aftL 299 4,84009
6bRaz 281 4,95502
6dC1q 291 4,64354
6dOJV 296 4,63166
6dSYo 294 4,55385
6ecEU 293 4,79621
6ewcj 288 4,65212
6exvg 288 4,56522
6eyWI 294 4,89170
6eyor 292 4,58341
6g0U7 283 4,41789
6g5l1 288 4,61143
6gwHg 296 5,16214
6ijfN 281 4,88721
6jnr7 299 4,69799
6jz6f 288 4,47086
6khSh 282 5,25825
6lQBR 288 4,59585
6mCqZ 282 5,28872
6mfbH 297 4,74983
6mvQi 288 4,52395
6p1FG 288 4,62552
6tGX8 293 4,88920
6tGqt 294 4,67276
6tqHe 269 4,66264
6vSbO 288 4,66849
6wNiW 296 4,74977
6wceP 288 4,60660
701Y5 288 4,51469
703SE 294 4,72505
70Da8 294 4,64769
70Idq 293 4,64769
70p8A 288 4,65053
70uIq 294 4,58909
70vAa 288 4,59716
70ynn 297 4,64923
7152i 293 4,65229
71GP2 288 4,66849
71oMq 293 4,59142
7M76C 290 4,84668
7MIGM 294 4,60779
7MRTc 296 4,47257
7MgF1 292 4,57352
7N8ci 288 4,53663
7NbBz 279 4,70538
7NbRx 294 4,51952
7NdYt 288 4,61569
7Nu7a 288 4,54953
7OLb5 287 4,63274
7OXUx 294 4,63467
7OdKA 295 4,74983
7OrI8 294 4,57158
7P7E5 296 4,47257
7Rguh 249 4,93257
7UODr 282 4,49968
7YoSE 288 4,48218
7ZAgj 294 4,58164
7ZB1c 281 4,92228
7ZzaH 282 4,45700
7eVap 288 4,69538
7owa8 288 4,64110
7qHTh 281 5,08370
7qHvY 288 4,74642
7rCKW 288 4,69242
7rCgP 288 4,59710
7rCiv 290 4,71391
7vAAw 288 4,64132
84yhA 288 4,68805
88GHn 294 4,46677
88GX3 294 4,50093
8IEyO 288 4,60938
8b0j7 288 4,61546
8bEiD 292 4,51861
8bq31 288 4,66076
8hcrg 297 4,59227
8hjjs 292 4,60159
8hkA3 291 4,55567
8kQFk 294 4,44739
8lqxy 288 4,61217
8nTea 281 4,90170
8ncHh 288 4,66076
BLrK 288 4,71414
BLyi 287 4,59773
BVWP 287 4,64815
C4Xs 297 4,65053
C7e1 288 4,61569
CEMg 288 4,56522
CF6U 288 4,51469
CF81 288 4,54964
CLTM 294 4,65724
Cqd6 291 4,55567
D29S 260 4,66002
D9ef 288 4,60574
DBMS 288 4,47086
DBZZ 294 4,61728
Da07 260 4,69191
Dve0 292 4,49900
ERHL 297 4,71965
ExBJ 288 4,61569
Exwm 288 4,65781
F21E 294 4,61728
F6Pm 288 4,72397
HI3U 288 4,51349
HJGt 305 4,62211
HJqx 288 4,49786
HKUo 288 4,58119
HNlF 290 4,59330
HjOU 294 4,61728
Hk0u 288 4,45035
HkFd 288 4,58892
HmhE 292 4,76165
HnqJ 294 4,51952
HoA8 283 4,40544
HowB 288 4,62655
HvRB 294 4,57988
Hwbq 288 4,44716
HzzI 288 4,51020
JQ51 297 4,78013
JR01 287 5,02885
JVjj 288 4,64542
JZLi 288 4,54913
KN4Q 288 4,56687
KNLS 278 5,58707
KwbB 295 4,86590
Kwl9 288 4,58625
MQxm 297 4,76535
MRsu 288 4,72397
N7k7 293 4,53373
N7nk 288 4,66787
N7rC 288 4,64655
N8jY 295 4,45336
ND6z 288 4,46063
NDGl 291 4,59199
NDob 288 4,63530
NHgD 288 4,63621
NJPg 288 4,49513
NKWA 294 4,55908
NWEM 288 4,72408
NYke 288 4,68805
Na98 294 4,59040
Nazp 287 4,90335
Nngu 294 4,95246
Nr0U 288 4,49786
Nrnh 292 4,54601
NssO 292 4,63024
NszH 288 4,49110
NxxC 288 4,61427
O456 288 4,72397
O9g7 288 4,57766
O9gG 288 4,66787
OKSl 290 4,40573
OL1C 294 4,43494
OLrD 292 4,58909
OR5d 288 4,67833
Obii 294 4,54441
OkbN 216 4,61921
OqR3 288 4,41022
OzxR 281 4,95502
VNHg 293 4,82389
oBZB 281 4,99128
oBiG 281 4,97264
oCtM 294 4,83287
oDVS 297 4,61830
oEG9 292 4,57232
oGH3 288 4,44631
oPnH 287 4,69077
oQWG 296 4,74977
oW9R 288 4,71374
pPvk 288 4,56158
pPws 294 4,51241
par8 288 4,57971
q1W0 288 4,80974
q1ye 294 4,42619
qfBo 288 4,52861
rjWB 287 4,59028
rk0P 288 4,57505
rkbI 288 4,56067
ro1d 288 4,61427
wA2M 260 4,69237
wP5m 288 4,65855
wwDT 260 4,72431
wwJe 288 4,61586
wygy 288 4,54782
xlC2 288 4,51884
yaej 288 4,53339
yamV 288 4,57744
yb7e 288 4,62655
ygFl 293 5,01845
ylFN 288 4,76626
yo0M 294 4,60779
yoYK 292 4,69526
ypNJ 294 4,61728
yuDJ 292 4,59040
z6RN 305 4,53589
z6vY 297 4,63757
zhQI 288 4,63530
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_25333
7ocj2
 56 52,1% 184 1.882E-85
2 phalp2_10432
23svY
 92 35,2% 255 7.393E-55
3 phalp2_12732
7UP1W
 1 30,4% 279 4.093E-34
4 phalp2_5203
41aUo
 11 28,9% 221 7.523E-30
5 phalp2_18736
K5Uf
 303 29,9% 277 4.947E-24
6 phalp2_5206
41nu6
 6 27,5% 240 3.181E-16

Domains

Domains [InterPro]
CHAP
Choline_bind_3
Representative sequence (used for alignment): 70eSG (306 AA)
Member sequence: A0A8S5MEJ9 (294 AA)
1 306 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257, PF19127

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctet217
[NCBI] 		2826409 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014887 [NCBI]
CDS location
range 946 -> 1830
strand -
CDS
ATGTTTACTTTAACGCAAGCAATCAATTATGTAAGAAATTTAGCAGACAACAACATTGGTGTTAACTTTGACGGGTGGTACGGTTGGCAATGTTGGGATTTAGTAGCAAAAGTAATGTATGAAGCTACTGGGAAAGTAGTTAATGGAAATGCTATTAATTTACCTGAATCTGCTGAAGCTCAAGGACTTAATGTTATTCAAGAAGGTCCGGGAGTTATCGCAAAAGCTGGTGACATCTTTGTAATGGATGTGCCAGGTTCGCCTTATGGGCATACTGGTGTAGTAATCGAAGATAGTGATGGCTACACTCTTAAGACTATCGAACAGAACGTAGATGGGAACTGGGACTATCTAGAAAACGGTGGCCCTGCTCGTTATCGCACACGCTCATACGCAAACATGGTCGCATTTATTCGTCCAGATTATGCTACTGATTCAGAAAACGTCCAACGTCCTAGCGGTTGGCTTGAAGACGAAAAGGGTTGGTGGTATAGAAACGATGACGGATCTTACCCTAAATCAAAATGGGAAAAGATTAATGGAAGTTACTTCCGATTTGATGACAATGGCTATGCTCTTGAAAACACTTGGTACCAAGATGATGAAGGTTTATGGTATTGGTTAAAACCAGGAGGATTCATGGCTGTTGGATGGCAATTAATCAATAACAAGTGGTATTTCTTCAATAACGTGGGAGAAATGCAAACAGGATGGATTCAGTATTTTGACAAGTGGTACTATTGCACAAACGAGAACGGAGACATGGTATCTAAAGAAGTCCGTAAAATTGGTGATAAATTCTACTACTTCAACGATAAAGGCGAGATGTTAGAACGTGCTGCAGTTTATGTAGACGAAAATGGCGTAATCCATTTCGAAGAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (70eSG) rather than this protein.
PDB ID
70eSG
Method AlphaFoldv2
Resolution 86.72
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50