Protein

Protein accession
A0A8S5M6G7 [UniProt]
Representative
5MKpS
Source
UniProt (cluster: phalp2_23384)
Protein name
Cell wall hydrolase autolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKKEEFIVILDNGHGKNTPGKRSVDGSLQEWAWARVVTTRLEKKLKDNGYNAVRIVTGEHDVPLQERCNLANQYVKKFGASNSCFISVHVNAAGNGTKWLNANGWSAYTTPGLTKADSIATKLYESAKKHLPGKRMRIDTTDGDSDIEANFYVLKHTNCPAVLTENLFMDNEQECKFLLSEEGITAIVNLHYDGIVDYINSL
Physico‐chemical
properties
protein length:202 AA
molecular weight:22538,2 Da
isoelectric point:6,59
hydropathy:-0,45
Representative Protein Details
Accession
5MKpS
Protein name
5MKpS
Sequence length
290 AA
Molecular weight
32415,45780 Da
Isoelectric point
5,48919
Sequence
MKILIDNGHGSNTPGKCSPGGRLKEYAYAREIAIRLEAELRKKGIDAERIVKEEIDVPLSERCRRANEYKANDTILVSIHCNAAGSGSEWMQPRGWEAWTSAGQTKADKLADSLYAAAERLLPDMKIRKDMSDGDADKESGFYILKHTKCPAVLTENLFQDNKEDVDFLLSEEGKRAIVDLHVQGIVNYLNNSKKINIMASVDLNFTKEDKVYVADIASPGKCIVQIERKESGWTTVFSKVDNLEFSEVAKFPDGPDKKSVIFELNIPEGMPVRIQSNKEVEIAKYVTEG
Other Proteins in cluster: phalp2_23384
Total (incl. this protein): 3 Avg length: 231,7 Avg pI: 6,78
Protein ID Length (AA) pI
5MKpS 290 5,48919
A0A8S5S9C8 203 8,25751
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37494
3aZmq
 1971 57,8% 211 1.575E-63
2 phalp2_38776
1gGIw
 71 43,8% 219 3.394E-48
3 phalp2_7949
zu48
 832 44,4% 189 5.571E-42
4 phalp2_22711
8625G
 10 35,1% 202 1.237E-29
5 phalp2_13925
foQI
 206 34,7% 193 3.107E-29
6 phalp2_33525
85Tz
 32 35,6% 191 8.562E-24
7 phalp2_24413
4m1OU
 1246 35,0% 194 1.317E-22
8 phalp2_23918
1NTlO
 42 29,9% 267 1.317E-22
9 phalp2_32087
63Erl
 43 29,7% 202 1.486E-21
10 phalp2_21129
DfJM
 1 32,6% 199 7.522E-20

Domains

Domains [InterPro]
Ami3
Unannotated
Representative sequence (used for alignment): 5MKpS (290 AA)
Member sequence: A0A8S5M6G7 (202 AA)
1 290 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctlRg1
[NCBI] 		2826692 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014834 [NCBI]
CDS location
range 28055 -> 28663
strand +
CDS
ATGAAAAAAGAAGAATTCATTGTCATACTTGACAATGGCCACGGTAAAAACACACCAGGAAAAAGAAGTGTTGATGGCTCTCTGCAAGAGTGGGCTTGGGCACGTGTAGTAACAACACGACTCGAAAAGAAGCTAAAAGACAACGGCTACAATGCTGTGCGTATCGTTACGGGCGAGCACGATGTACCTTTACAAGAACGGTGCAACCTGGCTAACCAGTATGTGAAGAAGTTTGGCGCTTCAAACAGCTGCTTCATCAGTGTACACGTAAATGCTGCCGGCAATGGCACCAAATGGCTCAATGCAAATGGATGGAGTGCATACACAACTCCTGGTCTGACGAAAGCAGATTCAATCGCCACGAAGTTGTATGAAAGCGCGAAGAAGCATTTGCCTGGTAAAAGGATGCGAATCGATACAACCGATGGTGACAGCGATATCGAAGCAAATTTCTATGTGCTCAAGCACACGAACTGCCCAGCGGTTCTTACAGAAAATCTGTTCATGGACAATGAACAGGAGTGCAAATTCTTGTTGTCAGAAGAAGGCATTACAGCTATCGTGAATCTGCACTACGATGGCATTGTAGACTATATCAATAGCCTATAG

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5MKpS) rather than this protein.
PDB ID
5MKpS
Method AlphaFoldv2
Resolution 94.25
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50