Protein

Protein accession
A0A8S5M073 [UniProt]
Representative
3sz7J
Source
UniProt (cluster: phalp2_31453)
Protein name
Cell wall hydrolase autolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 96% (predicted by ML model)
Protein sequence
MLICIDAGHCLSTPGKRCLKSIDPGETREWTLNSRVADKLEAILAGYDCRTMRVDDVTGQRDVTLSQRVAAANRAKADVYLSIHHNAGINGGSGGGIVAYEAPSHQRQSEVVRDAAYRYTVAATGLRGNRAQPLAEQSLYVLNYTTMPATLIELGFMDSTNDTPIILTEQFADQAAAGLAAALVEVYDLQTKGGGQVLLTAVPAGDLTVELVDRPKGECGDNCANAGYFANYSEAGEPFTLPVGHLVGDYKAAGKWTRHYCQERGRFQGDRFTFDAGKWSYANPLHGKAVSTLLISGGKARVEEIRTVPEGTDYAVSGIPVL
Physico‐chemical
properties
protein length:322 AA
molecular weight:34545,5 Da
isoelectric point:5,68
hydropathy:-0,21
Representative Protein Details
Accession
3sz7J
Protein name
3sz7J
Sequence length
333 AA
Molecular weight
35845,94390 Da
Isoelectric point
6,08145
Sequence
MLICIDAGHYIGTPGKRCLKRIDPGETREWTLNSRVADKLEAILAGYDCRTMRVDDVTGRRDVTLSQRVAAANRAKADVYLSIHHNAGINGGSGGGIVAYVAPSHQKQSEVVRDAVYRYTVASTDLRGNRAQPLAEQSLYVLNYTTMPATLIELGFMDSTHDTPIILTERFADQAAAGLAAALVEVYDLQPNGGGQVLMTAVPAEDLTVELVDRPKSECGDNCANAGYFANYSEAGEPFTLPVGHLVGDYKAAGKWTRHYCQERGRFQGDKFTFDSGGWSYANPLHGKAVSTLLISGGKARVEEIRTVPEGTDYAVSGIPVLRAGKACTTAQA
Other Proteins in cluster: phalp2_31453
Total (incl. this protein): 9 Avg length: 323,8 Avg pI: 6,17
Protein ID Length (AA) pI
3sz7J 333 6,08145
1ncE1 294 5,84824
3sUxW 392 6,02433
5PXWe 403 5,94334
6i2Pm 317 5,68347
7060s 265 5,37358
7O1u8 265 5,37358
n779 323 9,49015
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_5941
6ffn9
 61 65,4% 342 1.665E-131
2 phalp2_31486
3PO9t
 18 46,2% 212 1.996E-57
3 phalp2_36520
1qvSh
 1 30,6% 372 2.352E-30
4 phalp2_32481
1c5or
 14 26,5% 279 6.237E-16
5 phalp2_36719
6eCmw
 993 29,1% 206 1.603E-10
6 phalp2_30018
2o9Ij
 3 26,6% 281 1.189E-09
7 phalp2_35652
1qFqy
 5 26,0% 207 3.640E-08

Domains

Domains [InterPro]
Ami3
Unannotated
Representative sequence (used for alignment): 3sz7J (333 AA)
Member sequence: A0A8S5M073 (322 AA)
1 333 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctZDd15
[NCBI] 		2826664 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014788 [NCBI]
CDS location
range 20679 -> >21645
strand +
CDS
ATGCTGATCTGCATCGATGCGGGACATTGCCTGAGCACACCCGGCAAGCGGTGCCTCAAGAGCATCGACCCCGGGGAGACCCGGGAGTGGACCCTGAACAGCCGGGTGGCAGATAAGCTGGAGGCCATCCTGGCGGGGTACGACTGCCGGACGATGCGGGTGGACGATGTGACCGGGCAGAGGGACGTGACCCTGTCCCAGCGGGTGGCGGCGGCCAACCGGGCCAAAGCGGACGTGTATCTGTCCATCCACCACAACGCCGGAATCAACGGAGGCTCCGGCGGCGGCATCGTGGCCTATGAGGCCCCAAGCCACCAGCGGCAGAGCGAGGTGGTGCGGGACGCGGCGTACCGCTATACCGTGGCGGCCACCGGCCTGCGGGGCAACCGGGCACAGCCGCTGGCGGAGCAGAGCCTGTATGTGCTCAACTACACCACCATGCCCGCCACCCTGATCGAGCTGGGGTTTATGGACTCGACCAATGACACCCCCATCATCCTGACGGAGCAGTTTGCCGACCAGGCGGCGGCCGGGCTGGCGGCGGCGCTGGTGGAGGTGTATGACCTCCAGACCAAGGGCGGCGGGCAGGTCCTGTTGACCGCGGTCCCGGCGGGAGATCTGACGGTGGAGCTGGTGGACCGGCCCAAGGGGGAGTGCGGCGACAACTGCGCCAACGCGGGCTATTTCGCCAACTACTCCGAGGCGGGGGAGCCGTTCACCCTGCCCGTGGGCCATCTGGTGGGGGACTACAAGGCCGCAGGCAAGTGGACGCGGCACTACTGCCAGGAGCGTGGGCGGTTCCAGGGGGACAGGTTTACCTTTGACGCTGGGAAGTGGTCCTACGCCAACCCCCTGCACGGCAAGGCAGTCTCCACCCTGCTGATCTCCGGCGGCAAGGCCCGGGTGGAGGAGATCCGGACGGTGCCGGAGGGGACGGACTACGCCGTGTCCGGCATCCCCGTGCTGC

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3sz7J) rather than this protein.
PDB ID
3sz7J
Method AlphaFoldv2
Resolution 90.46
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50