Protein

Protein accession
A0A8S5LVW9 [UniProt]
Representative
6exQW
Source
UniProt (cluster: phalp2_18428)
Protein name
Membrane protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MASYPQCITDESTITVTAAYPYYSDGSHHGGIDTKHPTDFLAFAPQAGTIVTAHTWQGGKTGNDSWGNYIVVDMGKNRYWLAAHFKTQTHTVGEVLKAGDLIGMQGQTGNATGIHTHWEYWVGGRSTRYRQDPSQILGIPNAVGKYDVTWSADNPPGPGPEPPTPGKKAIPVWLLLKMARRYS
Physico‐chemical
properties
protein length:183 AA
molecular weight:20001,1 Da
isoelectric point:7,89
hydropathy:-0,51
Representative Protein Details
Accession
6exQW
Protein name
6exQW
Sequence length
386 AA
Molecular weight
43658,08480 Da
Isoelectric point
5,15452
Sequence
MATYKQCITDQKTIYESAGYPYYDGGGEHGGIDTVHDNYKAYAPLAGKVVWAQVWDGSTITGNMSWGNMILVEFEPNKYWLAAHFASQIWSEGDTIAQGQFIGTQGQTGNVTGTHTHWEYWDGGQTIAYRKDPSSILRIPNGVGTYNVTWDANTPQPKPPLPDAKWHAKNLYGYSRESSEAKDNAIMIYKALVQSLGWTLNAVSAVLGNMEWESGYNPWRWGWDEPLPSTDYRKEDIGYGLVQFTPPQKYIDADIAKSSPGYAPHFSDVMGSPNDGTAQCYFLSNATNLWYPVSPYNMSYAEFKASTKSPEYLASVFLDTYERPAYPEETRADREKAARYWYNYLVQYDPDTPPTPPEPPEPPTPGRKSMPIWMMCLGFYNRKRVI
Other Proteins in cluster: phalp2_18428
Total (incl. this protein): 65 Avg length: 373,6 Avg pI: 5,14
Protein ID Length (AA) pI
6exQW 386 5,15452
1jIAk 380 5,10956
23e6K 370 4,65758
2m3oP 381 5,10786
3IeO7 379 4,99884
3ra7k 379 4,87044
5KRVL 382 5,10786
5LBy2 379 5,09894
5Mj23 379 5,09894
5MsVW 379 5,09894
5N6zh 376 4,98975
5PZQy 381 5,09894
5PwEa 379 5,09894
5Q071 381 4,92865
5QHAu 387 5,23603
5Qhsn 379 5,09894
5SFgN 379 5,02368
5TQdi 376 5,18596
5TmXe 379 4,92865
5UxEe 379 5,08762
5Wvmy 379 5,10786
5YsLg 376 5,10786
5Z0VH 379 5,29116
5ZbFn 379 5,09894
60viW 381 5,19266
62Rhv 382 5,19266
64lDE 379 5,11661
64qGh 382 5,19266
65dk1 380 5,10070
66MHT 380 5,09894
66tsm 380 5,03130
677Hs 376 5,04022
68gUX 379 5,10070
69Bz2 379 5,11661
6ZQ66 376 5,19454
6aHJl 379 5,19454
6aMAn 383 4,90807
6ab8F 384 5,02050
6aztc 379 5,09894
6b5Zg 379 4,98975
6b5Zj 385 5,10070
6bSCr 381 5,19454
6bplF 381 5,19454
6dQeX 379 5,10786
6elTi 382 5,29907
6gTGX 379 5,04022
6hrJT 379 5,19266
6kbXJ 372 5,07182
6m1sw 379 5,10786
6nX2i 380 5,09894
6nZrp 380 5,19454
6o6Xk 379 4,98975
6oOyi 382 5,10070
6qQM2 384 4,96246
6sOkX 380 5,10786
6tC2j 379 5,09894
6tqN6 379 5,10786
7VWc0 380 4,88516
7XxBj 381 5,01862
7Yp2h 386 4,73886
859mW 379 5,03277
8oOCP 372 5,00112
jq7z 376 5,03130
A0A8S5RLT5 187 6,63779
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11847
8uHLg
 5 28,0% 350 4.532E-25

Domains

Domains [InterPro]
PET_M23
Phage_lys2
Disordered region
Representative sequence (used for alignment): 6exQW (386 AA)
Member sequence: A0A8S5LVW9 (183 AA)
1 386 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551, PF18013

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctoyw14
[NCBI] 		2826578 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014751 [NCBI]
CDS location
range 4516 -> 5067
strand +
CDS
ATGGCAAGCTATCCACAATGTATCACGGATGAGAGCACAATTACAGTGACCGCAGCATATCCGTATTATTCGGACGGCTCGCACCATGGCGGCATTGACACCAAACACCCCACTGATTTTTTGGCGTTTGCGCCGCAGGCAGGAACGATTGTAACTGCGCACACTTGGCAAGGTGGCAAAACCGGCAATGACAGTTGGGGTAATTATATCGTGGTGGATATGGGCAAAAACCGTTATTGGCTGGCGGCACATTTTAAGACACAGACACACACGGTCGGAGAGGTGCTCAAAGCTGGCGATTTGATTGGCATGCAGGGTCAGACCGGCAACGCAACCGGCATTCACACCCATTGGGAGTATTGGGTTGGTGGACGCTCTACTCGATACCGTCAAGACCCGTCACAAATTTTGGGCATCCCTAACGCAGTTGGCAAGTATGATGTAACTTGGAGTGCAGACAATCCGCCCGGCCCCGGCCCGGAGCCGCCAACGCCGGGAAAAAAAGCAATACCGGTATGGCTATTGCTTAAAATGGCAAGGAGGTATAGTTAA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6exQW) rather than this protein.
PDB ID
6exQW
Method AlphaFoldv2
Resolution 89.56
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50