Protein

Protein accession
A0A8S5LUB8 [UniProt]
Representative
7t5S8
Source
UniProt (cluster: phalp2_36884)
Protein name
NlpC/P60 family
Lysin probability
100%
PhaLP type
endolysin
Probability: 53% (predicted by ML model)
Protein sequence
MTVKELTDYAKSFAGKVKYVFGGNDVENGQLDCSSYIQAVYRKAGVELPRTTQEQAKIGTYVKPEDAKEGDMVMFQNTYTNGISHVGYYLGNGKVLHNSSNGITISDLTSGYYAEHFSQFRRVLDDKTMAAVDIGGVENSGEDVSLNGGIWYVVVRMVTIALAILFGMLFFVKSMNLEV
Physico‐chemical
properties
protein length:179 AA
molecular weight:19728,2 Da
isoelectric point:5,35
hydropathy:-0,09
Representative Protein Details
Accession
7t5S8
Protein name
7t5S8
Sequence length
619 AA
Molecular weight
68568,71300 Da
Isoelectric point
9,42529
Sequence
MKLDYKSDRPELQVMYFNKGILHRMTEVAESVSIKGDVAQAARECSINFANTTKGIQRIFDIVNGQEVRIMSGEMEVFRGTVRSFERHSDGRDSLIAKDGNEYLVKNTVNVKFIEKTATQIIKTLCGNYGIAVGKLADTKHKIPRYIMRGKTIYDVFITALTMTQKVTGKRYMLHNVKGKLTLEVVQPAQEWLRYEQGKNLISASYSESIEDTRTQILYTGGDEKSPYKVVVKKNTDKYGIMQHVEHNSDANQSALPGLANALLAELSKPQTEMNIKVLGIRNMVAGMAVVVQDNLTGIRGTYFVLADAHEYIAGGVHVMDLTLSKTLDLPVLEYEPPDESSDDPDSGKSAEYDFPYSTGWVATAYDPMLGGINTSGDPRTTATSTRWAYNRTIAVDPKVIPYGSVVAIKVPSMPKYNGMYLAEDTGGAIKGKRIDILIQGKSATAAFGRRDVEVAILEKGKGAPDARAKAKTWDSIKRKWNTKKEQKGVDKAAKGKAAEILKTAHSYKGKLRYVFGSKDLPNGKSDCSGFISYVFNRHGIKLPHGTSAQIRLGKSVNKAEAIPGDLVFFQNTYRKGVSHVGVVTRKGYCISMHNSGCTEHTYTTGYWGKHYMSIRRVL
Other Proteins in cluster: phalp2_36884
Total (incl. this protein): 17 Avg length: 529,0 Avg pI: 8,95
Protein ID Length (AA) pI
7t5S8 619 9,42529
1Gxp4 646 8,98362
1cmvH 619 9,91648
1mHnl 620 9,92589
3dJLe 618 9,22686
75TSO 620 9,89514
7BysC 615 9,13635
7d9un 657 9,13396
7dBZc 620 9,91035
7nHp4 641 9,42626
7oveb 455 9,18225
7s1x3 531 9,20410
7sJFV 619 9,45295
7xRvu 431 9,16974
7yjMk 324 9,27715
A0A8S5VUE2 179 5,59520
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_9548
1c6mm
 1 38,3% 449 3.353E-103
2 phalp2_3094
3MMk4
 6 28,5% 714 6.036E-92
3 phalp2_27798
7xQBg
 127 28,7% 591 3.087E-76
4 phalp2_2344
4SDRd
 25 24,6% 620 8.710E-68
5 phalp2_22078
5KWSa
 64 21,7% 465 1.094E-28
6 phalp2_25540
3onVx
 2 24,4% 422 1.006E-26
7 phalp2_34789
3xruw
 12 19,5% 587 9.595E-26
8 phalp2_23526
7aLOU
 1 18,5% 582 1.259E-20
9 phalp2_33801
1gwmB
 2 20,2% 578 2.061E-19
10 phalp2_36355
pLVt
 6 20,8% 567 6.299E-19

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Tectiviridae sp. cthzn51
[NCBI] 		2826821 Kalamavirales > Tectiviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014741 [NCBI]
CDS location
range 11094 -> 11633
strand +
CDS
ATGACTGTAAAAGAATTAACCGATTATGCGAAATCGTTCGCCGGGAAAGTAAAATATGTTTTTGGCGGTAATGACGTAGAAAATGGTCAGCTAGATTGTAGTTCATATATTCAGGCGGTATATCGAAAAGCTGGGGTTGAATTACCTAGGACTACCCAGGAACAGGCAAAAATAGGAACATATGTGAAACCGGAAGACGCCAAAGAGGGCGATATGGTTATGTTCCAGAATACATACACGAATGGTATTAGTCATGTTGGTTATTATCTTGGAAATGGAAAAGTATTGCATAATTCAAGTAACGGCATTACAATATCCGATTTAACATCAGGATATTATGCCGAACATTTTTCACAATTCCGCAGGGTCTTGGATGATAAAACCATGGCGGCAGTAGATATCGGCGGCGTGGAAAATTCTGGCGAAGATGTTTCACTGAACGGTGGCATTTGGTATGTCGTTGTGCGTATGGTGACGATTGCTTTAGCAATTCTTTTCGGTATGTTATTTTTTGTAAAAAGTATGAATTTAGAAGTATAA

Gene Ontology

Description Category Evidence (source)
GO:0003677 DNA binding molecular function None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)
GO:0016020 membrane cellular component None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7t5S8) rather than this protein.
PDB ID
7t5S8
Method AlphaFoldv2
Resolution 84.95
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50