Protein

Protein accession
A0A8S5LP63 [UniProt]
Representative
3VGN3
Source
UniProt (cluster: phalp2_2168)
Protein name
CHAP domain protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 95% (predicted by ML model)
Protein sequence
MSVIDELTRIAKGQIGNNGSKYRKWFYNRTSDYYGVNWCAVFISWLFNQVNGLGKYIVKSDGAGSIPRESIAAGLKGTWYESEYSAGSTRPLAGDIVVFTWNGIGRVPGQDKYYSNHIGYVYAVDSSYIYTIEGNTGSDSADYSVVAYRQYSRTSGKVNGYYRPYYNQKEDDEMNFKKGDKSDGVLAYKSLLQQGQKLGIIKSKVDNTNSFGGGTYKATLEVQKKFKLEQDGVAGKNTITALRNAINKALGSLSVGGTMVKGDINLGVYAVKRSLQTAHAAGIIKSNCDSKNGFGTGTEKCVKEIQKIACLKPSGIVDKGVINAINNLIEKRLTK
Physico‐chemical
properties
protein length:335 AA
molecular weight:36679,0 Da
isoelectric point:9,44
hydropathy:-0,43
Representative Protein Details
Accession
3VGN3
Protein name
3VGN3
Sequence length
342 AA
Molecular weight
37816,41040 Da
Isoelectric point
9,36566
Sequence
VDKDIVYKDFSYIKQRGMNGYKAAKNTNVKTVVNNDRDTFVNKMKTYVGTNGKRVCSGVGLNYVDEWCAYLISLGMLECNYIGKYIKNIEGGAGSIARFSDGIYGGFFKKGAKLPEPGDIVMFRYSSIAYYADKDRYFSDHVGVVVETRANSIITVEGNIKGNDCKTSTCDYVTHSLSESSVYAFYRPYWRTTTTTSTGTTKTTTVKTKTDGNEIYQINSSAVVDYDVIVTSDNGVNIRQGASTTYKILGAVPYNVKLHVSRATSGGGHTWGLIEYDGVKGWIALTYTKKYNKAQPVYYTVKAGDTLSGIAAKYKTTVSTLVKLNNIKNPDLIYGGQKIRIK
Other Proteins in cluster: phalp2_2168
Total (incl. this protein): 9 Avg length: 305,9 Avg pI: 8,71
Protein ID Length (AA) pI
3VGN3 342 9,36566
3e1Yh 301 8,33500
3idfM 297 9,05035
40DAS 294 8,70596
40Fws 302 9,06176
4JXnm 288 9,19798
4SKYb 295 5,68341
7DJw7 299 9,56287
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_4009
11iJK
 7 38,7% 333 1.038E-78
2 phalp2_6929
2LVGE
 3 25,8% 363 6.892E-25
3 phalp2_10891
4yt2F
 36 24,5% 277 3.977E-21
4 phalp2_9136
6d0dy
 3 25,6% 292 1.036E-19
5 phalp2_7368
4xoTh
 314 25,0% 264 1.982E-18
6 phalp2_12538
16lqa
 19 24,5% 411 2.903E-16
7 phalp2_30942
13AWP
 189 21,9% 251 3.888E-16
8 phalp2_29393
1dfbb
 105 23,3% 321 1.249E-15
9 phalp2_13490
4Oiht
 65 24,4% 229 5.526E-12
10 phalp2_33156
7DPYX
 1 22,7% 330 9.817E-12

Domains

Domains [InterPro]
Disordered region
Unannotated
SH3_3
LysM
Representative sequence (used for alignment): 3VGN3 (342 AA)
Member sequence: A0A8S5LP63 (335 AA)
1 342 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476, PF08239

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. cto6l14
[NCBI] 		2827590 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015887 [NCBI]
CDS location
range 20394 -> 21401
strand +
CDS
ATGTCAGTAATTGACGAATTAACAAGAATTGCAAAAGGCCAAATAGGAAACAACGGAAGCAAATACCGCAAGTGGTTTTACAACCGTACAAGCGACTACTACGGTGTAAACTGGTGTGCGGTTTTTATAAGCTGGCTATTTAACCAGGTAAACGGTTTGGGCAAGTATATTGTAAAGTCTGACGGTGCTGGCTCAATCCCACGCGAGAGCATCGCGGCAGGACTAAAAGGCACATGGTATGAAAGTGAGTATAGTGCAGGTAGTACACGGCCACTAGCTGGCGACATCGTTGTATTTACATGGAACGGTATAGGCAGAGTGCCGGGACAAGATAAATATTATAGCAATCACATCGGATATGTGTATGCAGTTGACAGCAGCTATATTTATACGATAGAGGGCAACACAGGAAGCGACAGTGCAGACTATAGTGTAGTTGCATACAGACAATACAGTCGCACAAGTGGCAAAGTCAACGGTTATTACAGACCTTACTATAATCAAAAGGAGGACGACGAAATGAATTTTAAAAAGGGTGATAAATCAGACGGAGTATTGGCGTATAAGTCATTACTGCAGCAGGGTCAGAAATTGGGCATAATTAAGTCAAAGGTAGACAATACAAACAGCTTTGGCGGCGGTACTTACAAGGCAACCTTGGAGGTGCAGAAAAAGTTTAAGCTTGAGCAGGACGGCGTTGCCGGTAAAAACACAATTACGGCACTGAGAAACGCTATAAACAAGGCGCTGGGCAGCTTATCTGTCGGCGGTACAATGGTAAAGGGTGACATTAACTTGGGCGTGTACGCAGTCAAGAGGAGCTTACAGACCGCACACGCAGCAGGCATTATCAAGAGCAACTGTGACAGTAAAAACGGCTTTGGCACCGGCACAGAAAAATGTGTTAAAGAGATTCAAAAAATTGCATGTCTTAAGCCGTCGGGCATCGTTGATAAGGGTGTCATTAATGCTATTAATAACCTAATAGAAAAGAGGTTGACAAAGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3VGN3) rather than this protein.
PDB ID
3VGN3
Method AlphaFoldv2
Resolution 71.34
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50