Protein

Protein accession
A0A8S5LK67 [UniProt]
Representative
NN8X
Source
UniProt (cluster: phalp2_16716)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTLQEFKAALLDAKEIIQDKARGLGRDVKAYCHWTGGDYNTDSDDYHICIRGDGTIINTLPLYMTPEATYHRNTGSIAITLDCCRGYTAWSHEDVELGDCPPTDAQIECLAQVIAVICDVMEIPVDIQHVMTHAEAADNMDGEYYHEPYGPENGCERSDLTILHAGEEWMSGGDILRGKAIFYMNQRSA
Physico‐chemical
properties
protein length:189 AA
molecular weight:21066,4 Da
isoelectric point:4,51
hydropathy:-0,35
Representative Protein Details
Accession
NN8X
Protein name
NN8X
Sequence length
136 AA
Molecular weight
14276,76900 Da
Isoelectric point
4,90960
Sequence
VIGDGALDALHAATYRRNSGSVSIALLGCVGATTEDLGAEPPTAAQIEGLATAVAALADGLWLTIDIARIMTHGEAADNADGVCAHAPYGPRTTCERWDLEYLGTAESPVFTPWAKDGTRGGDVLRGKAEWYRQHK
Other Proteins in cluster: phalp2_16716
Total (incl. this protein): 4 Avg length: 178,3 Avg pI: 4,86
Protein ID Length (AA) pI
NN8X 136 4,90960
A0A8S5PYW3 182 4,60353
A0A8S5U2J0 206 5,43144
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_26583
8s4n7
 984 55,9% 134 9.442E-44
2 phalp2_12016
7M9JJ
 1 75,0% 84 1.683E-39
3 phalp2_32054
5Hyk1
 3 38,0% 121 7.213E-21
4 phalp2_15223
QCVp
 291 24,3% 115 4.152E-05

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): NN8X (136 AA)
Member sequence: A0A8S5LK67 (189 AA)
1 136 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctXPh6
[NCBI] 		2827578 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015862 [NCBI]
CDS location
range 38267 -> 38836
strand +
CDS
ATGACACTGCAAGAATTCAAAGCAGCGCTTTTAGACGCAAAAGAAATCATACAAGACAAGGCACGCGGGCTGGGGCGTGATGTAAAAGCGTATTGTCACTGGACTGGCGGAGATTACAACACGGACAGTGATGATTATCACATATGTATCCGCGGAGACGGGACAATAATTAACACATTACCGTTATATATGACTCCGGAAGCAACATACCACCGAAACACGGGATCTATCGCAATCACACTGGACTGCTGCCGCGGTTATACGGCGTGGTCGCATGAAGACGTGGAGCTCGGAGACTGTCCGCCGACCGACGCGCAGATCGAATGTCTGGCGCAGGTCATCGCAGTCATCTGTGATGTAATGGAGATACCGGTAGATATACAGCATGTCATGACTCATGCCGAGGCTGCAGATAACATGGACGGTGAGTATTATCACGAACCGTACGGACCGGAAAACGGATGCGAAAGATCAGATTTGACGATCTTACACGCAGGAGAAGAGTGGATGTCCGGCGGAGACATCCTTCGCGGCAAAGCTATATTTTATATGAATCAAAGGAGTGCGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (NN8X) rather than this protein.
PDB ID
NN8X
Method AlphaFoldv2
Resolution 94.47
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50