Protein

Protein accession
A0A8S5LDK5 [UniProt]
Representative
6ZeMl
Source
UniProt (cluster: phalp2_9258)
Protein name
Endodeoxyribonuclease I
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKTIDSIIIHCSATRAGQDLRAKDIDRMHRQRGFSQIGYNFVIDLDGTVENGRPLSIDGAHCSTKGFSGISYNKHSIGICYIGGLDANGKPADTRTPAQRASLREQVAKLCKEYPIVEVLGHRDTSPDLDGSGEVEPAEYIKACPCFDVRSEFSNFLRNTVIRP
Physico‐chemical
properties
protein length:164 AA
molecular weight:18058,2 Da
isoelectric point:6,94
hydropathy:-0,42
Representative Protein Details
Accession
6ZeMl
Protein name
6ZeMl
Sequence length
98 AA
Molecular weight
10939,13840 Da
Isoelectric point
6,56947
Sequence
MQPEELISNGVKGYNSETINVAYVGGIDKSGKGVDNRTDAQRASLRKLLGELRSRYPKAKIQGHRDFSPDTNGNGIVDPWERIKECPCFDAIPEYKDL
Other Proteins in cluster: phalp2_9258
Total (incl. this protein): 429 Avg length: 154,6 Avg pI: 7,03
Protein ID Length (AA) pI
6ZeMl 98 6,56947
165XH 83 6,28812
1HuI7 164 6,21991
1JRnT 86 8,02614
1NABx 114 8,84011
1YaXa 113 9,30106
1cMPk 162 6,50297
1cuaq 162 5,47220
1gFIT 164 6,11391
1k2zM 93 8,86996
1lYaX 164 6,50257
1mYNh 164 6,28977
1mi9V 164 7,62639
1n3k3 164 8,52093
1nQwn 113 7,75798
1nRbx 169 8,52912
1nYaM 196 6,17370
1nutG 163 6,93694
21EXV 163 6,18655
21Ivs 166 8,51268
21oV1 166 8,73136
21sA8 163 6,18695
2396z 162 6,50297
23HNm 165 8,12258
23rZR 167 7,61957
23syi 163 6,58067
24DlT 163 9,05518
24E8S 163 6,18950
24TrE 178 8,23547
24puT 166 8,72156
24qcY 163 6,51002
2BkW 160 7,66146
2HAB 164 6,19104
2VR8z 80 9,60851
2czxD 71 4,97474
2fBjb 145 7,84356
2fMq5 98 5,55206
2lSwl 164 7,62327
2lXEt 164 6,19996
2mf95 163 5,62316
2mhf9 166 6,05457
33BRR 73 9,55468
38H6l 166 6,20019
3AM4G 89 4,21606
3DP7a 72 5,27940
3GMzG 168 6,51229
3TIKt 157 6,50849
3VMiA 165 7,61321
3Vp3u 149 8,28872
3Wzed 166 8,50481
3ZD7Q 160 5,93816
3ZEjF 164 7,60286
3ZPOk 163 8,90503
3ZTYs 164 6,99793
3bY36 167 7,64504
3dRuA 164 6,50900
3fV4e 160 5,93816
3fVXT 170 5,75577
3gR1J 165 5,66562
3gUH2 162 5,72070
3gUHf 162 5,72712
3iAFH 163 6,50911
3j3gQ 164 6,43494
3jX6N 205 5,95982
3k3em 166 6,51241
3kHD8 164 6,28539
3kS9J 186 5,96772
3lB7j 163 5,52449
3lGHO 175 6,40680
3lGaA 164 6,50911
3lNSK 164 7,12769
3lQ3P 164 6,50621
3lW7B 164 6,50399
3lacg 163 6,57925
3lnux 164 5,73349
3lnxp 164 7,63253
3m4jU 164 6,94279
3m69s 164 6,50536
3m9bo 157 6,28761
3mcFC 163 6,93694
3met1 164 6,50849
3mhIS 161 5,83915
3mkMQ 164 6,50399
3mxA4 163 6,20065
3opoM 164 6,93932
3p7TD 175 6,40612
3poLo 164 5,70234
3qSGY 163 5,83494
3qccn 168 6,51218
3qepf 205 7,58604
3quKz 164 6,94586
3qx6D 163 6,58073
3rQLV 163 6,04815
3rYYI 198 7,64305
3rYpY 164 6,51030
3s883 163 8,71640
3sIfA 164 6,50621
3sLRi 166 6,94103
3sW91 175 8,13560
3seVF 159 5,84728
3sytm 164 6,57982
3t4Do 163 6,58073
3t6of 164 6,50388
3tCRa 163 6,58186
3tEeP 164 6,50911
3tTk8 164 6,50496
3tfMw 164 6,94620
3tjrz 164 8,20162
3uB83 158 6,28835
3uBJF 186 7,09597
3uO9H 164 8,22805
3ueFp 164 8,21451
3uqGT 163 6,15256
3vE3u 164 6,50820
3vQ2Q 104 5,56769
3vQcI 164 7,63236
3vZGY 163 7,11200
3vs76 164 6,94353
3vwzD 164 7,12962
3w0xZ 186 6,23350
3w7x5 165 6,99383
3wCRb 164 7,77593
3wI6L 164 6,94330
3wRLX 164 5,72263
3wRb7 167 8,53756
3wd4w 164 6,50797
3wfjK 159 6,99747
3x1z3 163 6,58073
3xWmy 186 7,09597
3yWZs 158 6,50962
3ym4v 158 6,05360
3yqZT 164 6,94757
4KL0m 90 9,25323
4KZ0K 80 6,89181
4KZeL 78 4,81554
4Na4D 87 6,03121
4VDz6 164 5,93657
4VFPV 164 5,70234
4VFf3 164 6,50525
4Vssf 168 5,94873
4X2Rm 98 5,60992
4Xgik 105 7,87702
4XqdQ 87 7,76832
4k6H0 106 8,86004
4k7Q6 170 5,96948
4k9D0 163 6,20161
4qsvF 81 9,41246
4xtPp 163 6,64456
4z1Lh 164 6,94705
4z3Ts 166 6,29125
4z86e 74 9,34361
53j1f 100 9,32511
53qHB 71 9,13422
556Re 61 9,67453
5CXgc 52 7,98965
5JVPu 163 5,93185
5KY94 164 7,62929
5LNwg 163 6,58175
5LPD7 163 6,58084
5LlaE 164 8,21458
5M818 169 6,94700
5MUoL 163 6,93739
5NUPx 164 6,94552
5NYKB 163 6,98707
5NoZi 164 8,20156
5O7gY 163 5,82971
5ODHh 164 8,20800
5OHqf 169 6,51116
5OKDN 168 7,62009
5PSEG 164 6,19405
5QJSI 168 6,51229
5QQPt 163 6,64149
5QUqm 159 6,57806
5Qi3d 159 6,28909
5Qmkc 117 6,27772
5RcRU 163 6,58073
5S4EG 163 6,58073
5SI5u 164 7,62929
5SODa 164 6,50644
5SQcq 159 5,93936
5SfsK 164 6,94404
5Sp8b 164 6,18848
5T141 100 8,77055
5U1SO 164 6,94109
5U6wP 168 8,16810
5Ui1F 164 6,51116
5Uwsz 164 6,50957
5V3Eq 163 6,19775
5V4xb 164 6,28761
5VVwd 157 6,05008
5W6b2 164 6,94478
5WALS 196 6,40811
5Wnh1 130 8,91638
5XEvb 164 6,94177
5XUZN 163 6,58186
5XXAM 164 8,53763
5XbwH 168 7,62009
5Xlo3 164 6,50633
5Xod4 164 6,98724
5XuUv 159 6,57914
5YHyR 164 6,20275
5YsQ5 168 6,20184
5ZTTK 163 7,61696
5Zghr 186 7,73410
5ZwpV 163 6,28670
5mMGQ 56 9,81346
5vDS3 98 7,30560
5ywWl 88 8,73329
60PgF 168 7,63304
60Pot 164 6,56322
60Ppd 164 6,19712
60hBd 164 6,29125
60hXL 159 5,84739
60sE2 164 6,94319
60ydj 164 8,51281
61THx 164 8,20800
61aaH 168 7,63049
61o5n 97 5,88252
62BMc 168 7,62009
62C02 158 6,28448
62rtw 163 6,94200
63Be9 164 6,58067
63Q9N 159 6,06321
63QIG 157 5,93475
63dWm 178 8,71846
64BnK 168 7,62009
64Pmk 168 7,62009
64Qzl 163 5,62316
64WZN 163 6,57908
657jQ 164 6,50496
65LwA 168 6,94501
65P3W 164 6,50633
65p8S 164 7,63174
660oC 161 6,58419
668H5 163 6,58084
669KX 163 6,19587
66Bgg 157 6,57817
66EyG 160 7,65805
66GeC 164 7,76639
66QXw 165 6,58300
66VUR 164 6,50388
67Tj0 168 6,99344
67rzL 168 8,18209
685tu 164 8,19530
686K3 163 6,99719
68X3Y 168 7,62009
68tYh 168 6,94501
696O5 168 8,18202
69N44 157 6,99520
69OKC 163 6,58186
69Om0 185 8,14895
69qsw 164 6,19604
69uJ9 157 6,57925
69xhf 168 7,62009
6DZuI 96 8,04561
6Dwnh 96 9,47951
6KNYA 96 9,07278
6R96a 89 9,69593
6YGY9 85 9,71856
6YXBZ 97 5,87507
6Yip6 168 7,62009
6ZiaL 168 7,62009
6a2h9 157 6,28806
6bOcu 163 6,04815
6bmwj 168 8,18209
6c1YJ 180 7,03840
6cDSb 150 7,00037
6cFBX 166 6,51252
6cxHq 168 7,63077
6d94y 164 6,93819
6dW8Q 164 6,93444
6e2pj 169 6,20292
6eJRs 164 7,63236
6egFb 165 5,50380
6eq0M 175 7,73456
6f7zz 164 8,22115
6fY1i 162 6,58073
6fxjV 163 6,50814
6gLkS 164 6,57970
6gVTS 164 6,50496
6gtID 106 5,08461
6hEqi 168 7,62009
6hW8e 163 6,50803
6hYyN 162 6,94200
6hbxQ 168 7,62009
6hu9k 166 5,72075
6iGEX 163 6,20019
6ioI9 168 6,99395
6iq1Q 168 7,63378
6j6Zk 168 7,62009
6jEBi 164 6,28761
6jlIb 168 7,62009
6jona 163 6,50615
6k19e 164 8,20800
6kPpm 164 7,63253
6kiX9 164 6,94342
6lkAi 168 8,18557
6mM7p 113 5,49169
6mUbk 169 5,72075
6mZYQ 163 6,50627
6mcHK 158 6,64427
6mqYp 168 8,49128
6mrmd 168 7,61724
6nXpU 164 6,94376
6nYEv 164 6,94478
6nkNa 169 8,52912
6nnIv 164 6,93932
6nzfa 163 5,43457
6pE3K 164 8,20800
6pZOs 168 8,17383
6qVey 164 6,94705
6qYoJ 164 6,50445
6r9Ly 168 7,62009
6rDH1 164 7,62327
6rDp4 164 6,94632
6rSOE 163 5,63061
6rmI5 164 7,62327
6s9fC 163 6,06207
6sVUb 164 7,63208
6stgg 163 5,93185
6svEn 163 6,94200
6swuf 164 7,62327
6tByA 163 6,50388
6tDRk 168 7,62009
6tEKK 163 6,58209
6tTFZ 163 6,98667
6tpjp 168 7,62009
6uZWg 164 6,94586
6ulvy 164 6,94705
6ur4I 159 6,28909
6uzUW 166 6,29278
6vej3 159 5,66863
6vtuv 163 5,62327
6w027 164 5,49959
6wCvc 168 7,62009
706be 168 6,20371
70KtQ 164 5,93362
70RTM 69 9,61135
70UQm 168 7,62009
736PJ 164 7,63208
748S1 164 7,63515
76qJT 198 8,18550
79Gqz 164 6,58067
7C4tC 164 6,93887
7CkZg 84 4,35434
7MEvf 164 7,62554
7MMcA 164 6,50797
7NfJY 164 6,98832
7NgcZ 186 8,81794
7NjJz 164 6,19604
7OhNr 166 6,51252
7P2eU 164 7,62327
7TDig 149 8,57721
7X82D 168 6,51218
7XTCR 198 7,03908
7Ya0d 164 7,62327
7Z5IF 168 8,17964
7Zkme 168 7,63344
7aLAd 166 6,20195
7cjSm 164 6,18706
7cjWY 164 6,50058
7joGj 96 9,30261
7ptll 160 6,99878
7ptr2 163 7,61326
7tomi 97 9,72153
7urkH 96 9,30300
7x6wT 163 6,29130
7xSv9 163 6,93785
7y4ZJ 164 6,94330
7yxAc 149 7,59081
85Xhp 168 6,99446
85aOa 166 6,29278
87zk5 98 9,24375
8BE9s 72 4,93734
8EFfd 111 4,89835
8Eb8K 93 8,37201
8dhmQ 123 5,34323
8dnuM 168 6,99446
8eoyC 157 6,57828
8fJSf 168 6,51195
8hOew 159 6,28909
8kcQr 163 6,06207
8nYBa 94 7,80630
8oG7V 104 5,04147
8oNw6 163 6,06207
8r0oq 164 6,58107
8r8y9 163 6,50576
8rAgg 164 6,49962
8rLAE 186 6,51718
8sH1T 205 5,95982
BO9n 185 6,51303
BYZb 168 7,62009
CNRC 164 6,99275
DfDr 79 8,86461
EZ6U 164 5,93504
Ey2E 164 5,71615
F2NQ 158 6,29346
GuOQ 88 8,38768
IFtV 168 7,62009
JH5U 91 9,44418
KI6l 168 7,62009
LPEI 71 9,59027
MOiU 73 9,42981
MU1F 163 6,98667
N1Q 175 7,16321
NT4 165 6,19411
NutQ 164 6,28761
Nvka 164 5,83801
Nvmq 164 5,93657
OSP 164 6,50621
OnIH 164 6,63978
UNd 164 6,94103
Xkvg 76 9,07588
q9U4 164 5,93339
qaw7 164 6,94376
rmty 163 6,93694
rnyb 164 6,21991
xCDz 164 7,62566
ysvM 85 9,67898
A0A8S5SYK5 148 9,13248
A0A8S5T4U4 148 8,86990
A0A8S5TE36 154 8,99207
A0A8S5V352 168 6,99326
A0A8S5VRL6 164 6,94575
A0A9Y1MRQ9 168 7,63049
A0AAE9V2M5 168 7,63049
A0AAF0A696 168 7,63350
A0AAF0A847 168 7,63350
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11611
1k5JO
 2203 63,2% 98 4.099E-51
2 phalp2_25112
1plEg
 298 43,7% 96 4.728E-31
3 phalp2_25435
2NLUL
 9 34,7% 95 3.346E-27
4 phalp2_1572
7VT79
 79 35,9% 103 1.630E-26
5 phalp2_24958
obUW
 71 35,8% 92 1.457E-21
6 phalp2_25760
4OCuh
 74 38,4% 78 8.220E-19
7 phalp2_10774
3IYDg
 14 31,2% 96 8.740E-16
8 phalp2_25589
3Vd7e
 10 31,0% 74 1.200E-15
9 phalp2_2298
4Fmu3
 19 42,6% 75 7.371E-14
10 phalp2_19536
3DXjR
 12 32,5% 86 9.290E-13

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 6ZeMl (98 AA)
Member sequence: A0A8S5LDK5 (164 AA)
1 98 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctCCX1
[NCBI] 		2823567 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK014690 [NCBI]
CDS location
range 72610 -> 73104
strand +
CDS
ATGAAAACTATTGATTCGATTATTATTCATTGCTCGGCCACACGTGCCGGGCAAGATTTACGTGCTAAAGACATTGACCGGATGCACCGACAAAGGGGATTCAGTCAGATCGGTTACAATTTCGTGATTGATTTGGATGGTACCGTGGAGAATGGCCGTCCATTATCCATCGATGGTGCACATTGTAGCACAAAGGGATTCTCTGGCATATCATACAATAAGCATTCGATAGGTATCTGCTATATCGGTGGACTTGATGCGAACGGAAAACCTGCTGATACACGGACGCCCGCTCAAAGAGCTAGTTTACGTGAGCAGGTAGCAAAGCTCTGCAAGGAATATCCTATTGTGGAGGTTCTGGGGCATCGTGATACTTCTCCAGACTTGGACGGCAGCGGTGAAGTAGAACCGGCTGAGTATATCAAGGCTTGTCCCTGCTTTGATGTTCGTTCTGAGTTTTCTAATTTTCTTCGTAATACAGTGATCCGGCCATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6ZeMl) rather than this protein.
PDB ID
6ZeMl
Method AlphaFoldv2
Resolution 95.20
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50