Protein

Protein accession
A0A8F3E8Z8 [UniProt]
Representative
3Y9h2
Source
UniProt (cluster: phalp2_25598)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MVAPIIKMPNTEKHSGISGIPTQLLVLHSGESPLRGGYAQSLTQWGNIPLRDGGPEASWHWFVDPIAIVSMVDPIYAAWHASEANPMSEGFEQAGYARFSRAEWTTAEGMKQLDNLAWIMAQRALANGIPAVWLTTDQVEAVTKRGNRSIKGFALHRQIDPETRTDPGNDYPYDLLMERIKSYMAGKTPATSQEEYDMAAPTAKEIAQAFLREKAWDGTDKTVSHVLKALFEHDFVGGTSMPEGVALKDFVAYKLPGVIASTLAPALAKISGGTSVSKDEVAKIIHEAFAAEVGRLEATVTVAPTK
Physico‐chemical
properties
protein length:306 AA
molecular weight:33249,4 Da
isoelectric point:5,65
hydropathy:-0,20
Representative Protein Details
Accession
3Y9h2
Protein name
3Y9h2
Sequence length
318 AA
Molecular weight
34664,01050 Da
Isoelectric point
9,41240
Sequence
MVTPAQVAEKYLAMPSSKHSGKRSRTQMLTVHSAESPLRRGFAKSLTNWSNTTGVQASWNAFADPGVVVRAVHTAYAAWHASWANPISIGYETAAYAAFSRADWLTLEGRRMLERLAIEMAADAEIFDIPLRWLTGRQVNLIRAGNTSIKGLSAHRQIDPAYRTDPGDGFPYGYLLKRIKHHSGVKPASNKPKPIQKDELEMANLNTVTEAVIKAGPKLADIILDSPVQIRGDGASGKTTLRKKIAYLFHEQNRSYKAIQAVNAKVNKLTLEHAGIKAAVQAVDDSAGIEGARLEEIVGDRVDAALADVTLTLTNDES
Other Proteins in cluster: phalp2_25598
Total (incl. this protein): 19 Avg length: 321,0 Avg pI: 6,09
Protein ID Length (AA) pI
3Y9h2 318 9,41240
3PtKh 326 5,50084
3V3IC 313 5,82909
3X8wP 320 5,82034
40xmW 347 4,94905
6T6ri 295 5,80567
6T7Tg 349 7,73632
6Tdhp 354 7,72654
7b66I 264 8,38329
8LezI 327 4,90392
8MFna 330 5,65812
A0A0U4IQ42 327 4,90392
A0A3S9UN84 330 5,65812
A0A3G2KA11 320 5,59412
A0A3G2KIN3 320 5,59412
A0A6G6XIT3 313 5,42883
A0A9X9K1N7 320 5,59412
A0AA96GM07 320 5,59412
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_5425
2QySc
 1 27,9% 258 1.113E-26
2 phalp2_1243
oSGY
 19 26,2% 206 5.632E-19
3 phalp2_9231
6Te1j
 3 24,0% 216 1.021E-18
4 phalp2_5694
4FmvX
 16 25,0% 248 1.654E-15
5 phalp2_17457
7PxDe
 7 20,5% 214 1.053E-10
6 phalp2_39382
4Imdk
 1 22,1% 217 2.169E-04

Domains

Domains [InterPro]
Unannotated
Unannotated
Unannotated
Representative sequence (used for alignment): 3Y9h2 (318 AA)
Member sequence: A0A8F3E8Z8 (306 AA)
1 318 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Arthrobacter phage Rizwana
[NCBI] 		2836008 Tankvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MW712735 [NCBI]
CDS location
range 17371 -> 18291
strand +
CDS
ATGGTCGCCCCCATCATCAAGATGCCGAATACGGAGAAGCACTCCGGCATCTCCGGCATCCCTACCCAGCTGCTCGTGCTGCATTCCGGGGAGTCCCCGCTGCGCGGCGGATACGCCCAATCCCTGACCCAGTGGGGGAACATCCCGCTGCGGGATGGTGGGCCGGAAGCGTCCTGGCACTGGTTCGTGGACCCCATCGCCATCGTCTCGATGGTAGATCCGATCTACGCCGCGTGGCACGCCTCCGAGGCCAATCCCATGTCCGAGGGATTCGAGCAGGCAGGCTACGCGCGCTTCTCCCGGGCCGAATGGACCACCGCCGAGGGCATGAAGCAGTTGGACAACCTCGCCTGGATCATGGCCCAGCGCGCGCTCGCCAACGGCATCCCCGCCGTGTGGCTGACCACCGATCAGGTGGAGGCGGTCACCAAGCGCGGCAACCGCTCCATCAAGGGCTTCGCCCTGCACCGCCAGATCGACCCGGAAACCCGCACCGACCCGGGCAACGACTACCCCTACGACTTGCTCATGGAACGCATCAAGAGCTACATGGCAGGCAAGACCCCCGCAACATCCCAGGAGGAATACGACATGGCTGCTCCCACAGCAAAGGAAATCGCCCAGGCATTCTTGCGCGAGAAGGCATGGGACGGAACGGACAAGACCGTCTCCCACGTCCTCAAGGCTCTCTTTGAGCATGACTTCGTCGGCGGCACCTCGATGCCCGAGGGCGTGGCGCTCAAGGACTTCGTGGCCTACAAGCTGCCCGGCGTCATCGCTTCGACGCTGGCCCCGGCGCTGGCCAAGATCAGCGGCGGCACCTCCGTCTCCAAGGACGAGGTCGCCAAGATCATCCACGAAGCCTTCGCGGCCGAGGTGGGACGGCTCGAAGCCACGGTTACGGTCGCTCCGACCAAGTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3Y9h2) rather than this protein.
PDB ID
3Y9h2
Method AlphaFoldv2
Resolution 72.70
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50