Protein

Protein accession
A0A8D9FRU6 [UniProt]
Representative
7G1A0
Source
UniProt (cluster: phalp2_28796)
Protein name
Putative N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 96% (predicted by ML model)
Protein sequence
MKLSRLLRYGMAGKDIKHLQIRLGELKYADYLATGNFGPKTLKSVKKFQNDNGLSVDGVVGNKTWTYLFSGTIKPNNNEPIRVTPRKKFSLKPDEITPNGLEIFEQIMPDGEYVKKKTKKKIIYLHHTAGSHRPDWVIASWGRDRDKNGKPIRVATHYVIGRRSNGGDTTWDGKVFRAYDDNHWAWHLKAGNSKLDSESIAIEICNYGWAKKLDNGQFINWVGSEIPASEIVDLGEEFRDHRYYQKYTNEQIESLRKLIIYLTEKHDIDIEHGIYNKNWFGYDSTYLEPGQRGLRTHVHVRKNKSDCFPQNELIDMLNSL
Physico‐chemical
properties
protein length:320 AA
molecular weight:37045,6 Da
isoelectric point:9,28
hydropathy:-0,75
Representative Protein Details
Accession
7G1A0
Protein name
7G1A0
Sequence length
278 AA
Molecular weight
32007,78620 Da
Isoelectric point
6,60523
Sequence
MVIYEDILNKSEYKITNKNKKTIVIKHSSGNHNPENYINKLKLDRSKGGGEISVAPHYVIGNVSFKGDDKYDGKIHNILPINSFSNSIDCKKNGETINEHSVVIVLCSYSFLSKNSKNEYYNSVNDLVDNGLVCDLGKNFRRHRYWYEYSDRQIDSLNKLLLYLSNSLDIDLKKGIYQYLEEDNDIEDLPVLEIQKILNYKGILGINDKPLEVNGIMDGNTRYAIRTYKDSVKGFKNSFDYNDIAINSGEGLWVTSNFKRDTLDIYPNPKIIEMIKNF
Other Proteins in cluster: phalp2_28796
Total (incl. this protein): 2 Avg length: 299,0 Avg pI: 7,94
Protein ID Length (AA) pI
7G1A0 278 6,60523
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11040
7EhAU
 132 32,9% 258 8.353E-46
2 phalp2_28209
iKDC
 1185 29,3% 279 1.667E-43
3 phalp2_35105
5kI8h
 32 26,4% 276 1.904E-30
4 phalp2_4134
1HOCY
 3 22,1% 280 3.551E-26
5 phalp2_17917
Rszt
 866 27,1% 210 2.362E-20
6 phalp2_13122
8iXkc
 2 23,2% 215 3.613E-16
7 phalp2_11814
8vJeI
 1 22,9% 288 2.350E-14
8 phalp2_167
5yRR3
 9 30,8% 175 5.730E-14
9 phalp2_11998
38Ehm
 38 19,9% 216 1.293E-05
10 phalp2_1024
6U3Fm
 2 20,2% 188 1.721E-05

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 7G1A0 (278 AA)
Member sequence: A0A8D9FRU6 (320 AA)
1 278 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured marine phage
[NCBI] 		707152 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OU342829 [NCBI]
CDS location
range 511085 -> 512047
strand -
CDS
ATGAAACTAAGTAGATTACTTCGATATGGGATGGCTGGGAAAGACATCAAACATTTACAAATAAGACTAGGAGAATTAAAGTACGCTGATTATTTAGCTACTGGTAACTTTGGTCCAAAAACATTAAAGTCAGTTAAGAAATTTCAAAATGATAATGGATTATCCGTTGATGGTGTTGTTGGTAATAAAACATGGACATACCTTTTTAGTGGAACTATTAAACCAAATAATAATGAACCAATTAGGGTAACTCCCAGGAAAAAGTTCAGTCTTAAACCAGATGAGATAACACCCAATGGGTTAGAGATCTTCGAACAGATAATGCCAGATGGTGAATATGTGAAGAAGAAGACTAAGAAGAAAATCATTTATCTTCATCATACCGCTGGTAGTCATAGACCTGATTGGGTAATTGCATCTTGGGGTAGAGATCGAGATAAGAATGGTAAGCCAATTAGAGTCGCAACTCATTATGTAATCGGTAGAAGATCCAATGGTGGAGATACTACATGGGATGGTAAGGTATTCAGAGCTTATGATGATAATCATTGGGCTTGGCACCTGAAAGCGGGGAATTCAAAACTTGATTCTGAATCTATAGCTATTGAAATATGTAACTATGGGTGGGCTAAAAAATTAGATAATGGTCAATTCATTAACTGGGTAGGATCTGAGATACCAGCATCTGAGATAGTTGATCTTGGTGAAGAATTTAGGGATCATAGATATTATCAAAAATATACAAATGAACAAATTGAATCCCTTAGAAAATTAATTATCTATCTAACAGAGAAGCATGATATTGATATTGAACATGGAATTTATAATAAGAATTGGTTTGGATATGATTCTACTTACTTAGAACCTGGGCAAAGGGGACTTAGGACTCACGTTCATGTGAGGAAAAACAAGTCAGATTGTTTCCCACAGAACGAATTAATTGATATGTTAAATAGTCTATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7G1A0) rather than this protein.
PDB ID
7G1A0
Method AlphaFoldv2
Resolution 89.59
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50