Protein

Protein accession
A0A899J3S5 [UniProt]
Representative
7cDMo
Source
UniProt (cluster: phalp2_7770)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MPRVVYGNSFSENGWPMVNSEECTWVTVPGTSVSLQIQNGQPLAILRAFAADFNAYVEPLRDPDSACWTPTNSVSTSNHLSGTACDFNWNDHPFQVSYAGFSSKETATVRELLDFYEQTVFWGQDWQSPKDAMHFQVGYNTYQNPHTADFIARKIRADGFSTFRRSNKPNGGAPILAAATGLSEARSAEILPAVSDGLKASQCTNVNRIAMWLAQVGHESVSFKYTEEIAKGGRYAPYIGRTWIQITWDYNYRAFSEWCFERGLVPTRDYFVVNYRELADLKWAGLGASWYWTEQRPMNALTDAGDSATWKAGSITYRGFEAVTAAINGGTNGLADRRDRYNRALLQGEALLQLLNQEEDDMFTDDDRNLLRQVAGVRRPSLSPLRHLDEGDVNTCAGFAWTADGLTHPQFVAMAAKYGHMDSIRLLGEVAGADPVKYPDRQEDAALAKAILADVYAANPAALQRFVAQNGA
Physico‐chemical
properties
protein length:472 AA
molecular weight:52403,7 Da
isoelectric point:5,23
hydropathy:-0,38
Representative Protein Details
Accession
7cDMo
Protein name
7cDMo
Sequence length
319 AA
Molecular weight
34915,66170 Da
Isoelectric point
5,85546
Sequence
MVLRTENGWYQVPASSCEWTTIPGTNVTLQIQKGWPLTIMRAFAADFNAYVEPLRDPDSACWTPTNSVATSNHLSGTAMDLNWNSHPFQVLNAGFDAAKIATIRELLAFYEDTIFWGNDWTTPKDAMHFQMGYDTYNNSHTQDFINRKIRPDGYSTFRRGEAPSVDVAQVLSDAMGGRLSLDRYAQLLPAVTASLLACDCTNVNRIAMWCAQIGHESAGLYYTEEIASGAAYEGRADLGNTQPGDGVRFKGRSWIQITGRSNYTRLSAWAFSKGLILPQPTSSTTPPRSHPTSTPASAPLGTGWSPAPTSTPCPMPATS
Other Proteins in cluster: phalp2_7770
Total (incl. this protein): 152 Avg length: 446,3 Avg pI: 5,93
Protein ID Length (AA) pI
7cDMo 319 5,85546
7owdR 353 6,97297
A0A2Z5XVP6 317 5,28338
A0A3G8FU95 477 6,28374
A0A3G8FTV5 477 6,15250
A0A345MAV1 461 5,86314
A0A515MIU4 477 6,15250
A0A3G8FJG9 477 6,15250
A0A2U8UGP9 477 6,03519
A0A345MFL4 461 5,86314
A0A0F6YQE4 464 6,09959
A0A0P0M638 489 5,92708
A0A0F6YRS1 314 5,28554
G1FGA6 458 6,03377
A0A0M4RSF9 490 5,75645
A0A2P1JV09 477 6,15250
G8IB48 470 6,03439
A0A3G8FT87 477 6,15250
G3MDN4 489 6,15057
A0A097EVK7 477 6,15154
A0A076G858 317 5,52096
A0A7T1KSS8 481 4,88340
K0G1C0 477 6,15250
Q854X2 317 5,54876
G1D359 476 5,98790
S5YQM1 477 6,15250
Q5J5U7 477 6,03405
A0A2P1A0D3 477 6,15159
A0A2P1JZ43 477 6,08407
A0A125RPJ3 477 6,03519
A0A222Z0N7 455 5,96624
A0A2P1JYS3 477 6,15250
T2A9N1 475 6,23492
A0A411C415 477 6,15250
Q5J5L5 477 5,92572
A0A218M3J1 462 6,02473
A0A222ZRN1 490 5,71990
G1D9W3 477 6,15250
I3WX01 475 6,38844
A0A2Z5H1E3 477 5,82318
A0A345M636 477 6,03342
A0A385E0E1 477 6,15250
A0A5J6TEM7 314 5,41462
A0A5J6TTX6 316 5,50613
A0A5Q2WQL3 477 6,15057
A0A649V910 477 6,03519
A0A649VEG6 477 6,28374
A0A7G9V448 317 5,35318
G1EUX6 477 6,15250
S5Z6C2 316 5,25467
A0A2Z5XBM2 477 6,28454
A0A0A7RWC1 477 6,15250
A0A0B5A3P4 470 6,03439
A0A0K2CX93 477 6,15250
A0A0K2FL37 477 6,15159
A0A0M3ULG1 477 6,15250
A0A0N9SHC3 477 6,15159
A0A0U3TEY9 316 5,26275
A0A173GA43 316 5,37603
A0A1B1SEM6 316 5,26275
A0A1C9LXX9 470 5,92623
A0A1C9M331 477 6,15250
A0A1D8EPP0 316 5,26275
A0A1D8EZL3 477 6,15250
A0A1I9SB22 477 6,15250
A0A221J7D6 316 5,26275
A0A222ZTE1 316 5,26275
A0A249XQG4 477 6,03280
A0A2D1GCB5 470 5,92412
A0A2H4PC41 470 6,03445
A0A2L0HJ93 477 6,15250
A0A2L0HL33 477 6,15250
A0A2P1CCZ6 461 5,97499
A0A2P1CF39 477 6,15159
A0A2P1CJB4 477 6,15250
A0A2P1CJK8 477 6,03672
A0A2P1JT51 470 6,15426
A0A2P1N1N0 477 6,15250
A0A2U8UH67 477 6,15250
A0A2Z5H1M8 477 6,15250
A0A2Z5H7U2 477 6,15250
A0A345KUQ1 476 5,08848
A0A345KWR8 477 6,15159
A0A345L2H6 477 6,15250
A0A345MBR4 477 6,28386
A0A345MC09 477 6,15250
A0A385CZN7 477 6,15250
A0A385UFJ7 490 5,75645
A0A386K776 477 6,15250
A0A386KGU4 316 5,26275
A0A3G2KDJ2 316 5,26275
A0A411AYK0 477 6,15057
A0A411BN39 477 6,03229
A0A411BQ05 477 6,28386
A0A411BQB1 470 6,03439
A0A411BVM5 477 6,15250
A0A411BX14 477 6,15250
A0A411CH40 477 6,15250
A0A481VT81 470 5,92623
A0A481VU30 477 6,15250
A0A481VVP3 462 6,18160
A0A481VY69 458 6,03377
A0A481W070 477 6,15159
A0A481W0Q3 468 6,10146
A0A482JI77 470 6,03439
A0A4D6T5G4 477 6,15250
A0A514DFZ5 316 5,26275
A0A514U3R8 490 5,75645
A0A514U4J4 299 5,14799
A0A5B8RP98 477 6,15250
A0A5P8DE60 477 6,15250
A0A649V7F4 477 6,15159
A0A649VAE7 477 6,15250
A0A649VDN4 477 6,15250
A0A649VEW3 477 6,03405
A0A649VNU9 299 5,14799
A0A649VUW7 316 5,37603
A0A6B9JDZ5 316 5,26275
A0A7G8LQY1 477 6,15250
A0A7G9A2M9 475 6,23577
A0A7L8ZEL5 470 6,03445
A0A7M1CQ30 470 6,03439
B3VFY1 464 5,97846
B3VGZ2 464 5,97846
F6M822 316 5,26275
G1D4N2 477 6,28386
G1DTP8 470 6,03439
G8I6Q9 317 5,28338
I3WU42 475 6,23577
Q9B0B3 477 6,15250
R4JLP7 316 5,26275
R4TJ69 316 5,26275
S5XYA3 490 5,71990
S5Y7S0 477 6,15250
T2A8M5 475 6,23577
V5R3T9 464 5,97846
X2KSF5 477 6,15250
A0A899J014 465 4,74329
A0A976U908 490 5,88900
A0A9E7MBH1 477 6,08657
A0A9E7TSS8 469 5,88138
A0AA48Y4R1 470 5,92412
A0AA49B472 470 6,03445
A0AA49B4E1 477 6,15250
A0AA49BRD3 470 5,92412
A0AA96H1D1 477 6,20053
A0AAE7SCV9 477 6,15250
A0AAE7XDX7 490 5,75645
A0AAE9C334 477 5,92219
A0AAX4NNY8 464 5,86058
R4JHM2 386 6,27272
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24932
8Jrom
 307 58,4% 325 4.137E-140

Domains

Domains [InterPro]
PET_M15
Unannotated
Disordered region
Representative sequence (used for alignment): 7cDMo (319 AA)
Member sequence: A0A899J3S5 (472 AA)
1 319 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF13539

Taxonomy

  Name Taxonomy ID Lineage
Phage Mycobacterium phage prophiGD102-1
[NCBI] 		2813236 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MW584211 [NCBI]
CDS location
range 56072 -> 57490
strand +
CDS
ATGCCGCGGGTCGTGTATGGGAATTCGTTCTCTGAGAACGGGTGGCCCATGGTCAATTCCGAGGAGTGCACCTGGGTCACTGTGCCGGGTACGTCGGTTAGTCTGCAGATTCAGAACGGGCAGCCGTTGGCGATTCTGCGGGCATTCGCAGCGGATTTCAACGCCTACGTTGAACCGCTGCGTGACCCGGACTCGGCGTGCTGGACACCCACCAACTCGGTGTCAACATCCAACCACCTGAGTGGTACGGCATGCGATTTCAACTGGAACGATCACCCATTCCAGGTGAGCTACGCCGGATTCTCATCGAAAGAGACGGCAACAGTTCGTGAGCTGCTCGACTTCTACGAGCAGACCGTCTTCTGGGGGCAGGACTGGCAGTCCCCGAAAGATGCCATGCACTTTCAGGTCGGCTACAACACCTACCAGAATCCGCACACCGCGGACTTCATCGCCCGGAAGATCCGCGCCGACGGATTCTCTACCTTCCGGCGGAGTAACAAGCCGAATGGTGGCGCCCCCATCCTCGCCGCCGCTACCGGCCTGTCCGAGGCGCGTTCAGCCGAGATCCTGCCCGCAGTGTCCGATGGGCTCAAGGCCAGCCAGTGCACGAACGTCAATCGGATAGCGATGTGGCTGGCGCAGGTCGGGCACGAGTCGGTGAGCTTCAAGTACACCGAGGAGATTGCCAAGGGCGGGCGCTACGCGCCGTATATCGGGCGTACGTGGATACAGATCACATGGGACTACAACTATCGCGCATTCTCAGAATGGTGCTTTGAACGGGGTTTGGTGCCGACTAGGGACTACTTCGTTGTGAATTACCGGGAGCTGGCCGACTTGAAGTGGGCCGGCCTCGGCGCCTCTTGGTACTGGACCGAGCAGCGTCCAATGAACGCACTCACAGATGCCGGTGACAGCGCGACCTGGAAAGCGGGCTCAATCACCTACCGGGGCTTCGAAGCGGTCACCGCTGCCATCAACGGCGGCACCAACGGCCTGGCGGATCGCCGCGACCGATACAACCGCGCCCTACTTCAAGGCGAGGCGCTGCTGCAACTTCTCAATCAGGAGGAAGACGACATGTTTACCGACGACGACCGCAACCTTCTGCGGCAGGTGGCCGGAGTGCGGCGCCCGTCGCTCTCGCCGCTACGTCACCTCGATGAAGGCGATGTCAACACGTGCGCCGGGTTCGCATGGACAGCGGACGGACTAACCCACCCGCAGTTCGTGGCAATGGCCGCCAAGTACGGGCACATGGACAGCATCCGCCTCTTGGGTGAGGTGGCTGGAGCCGACCCCGTGAAGTACCCCGACCGGCAAGAGGACGCAGCCCTGGCCAAGGCGATCCTCGCCGATGTCTACGCCGCCAACCCCGCCGCCCTTCAGCGGTTCGTTGCTCAGAACGGAGCCTAG

Gene Ontology

Description Category Evidence (source)
GO:0008233 peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7cDMo) rather than this protein.
PDB ID
7cDMo
Method AlphaFoldv2
Resolution 85.95
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50