Protein

Protein accession
A0A898KB80 [UniProt]
Representative
6Tv9w
Source
UniProt (cluster: phalp2_12235)
Protein name
Peptidoglycan endopeptidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MPRALPNFSGLQRLEQTIKTRLEPLQRSMSFGSNAVTNTQIRKDPGVQARQATTNPGTANAQLTSNYRTKFDKTRDFSSRITQMTQTAAQQRRLQQMQSQLEAAQARTIQPVAARAGAQRGNNQAMPVANNYAGPINSKNPIRQQIVKAALSLQGTPYAWGGGGYGSRGSRGTGLGTQNVIGVDCSGLTQYAYGSVGIKIPRHSNSQTASGYRTNIGNAQPGDLVGWNRGGHVAIYIGNGMIMESRKPGTRASIRRLGANEGVYAVRLRLPGD
Physico‐chemical
properties
protein length:273 AA
molecular weight:29372,7 Da
isoelectric point:11,35
hydropathy:-0,64
Representative Protein Details
Accession
6Tv9w
Protein name
6Tv9w
Sequence length
349 AA
Molecular weight
35929,96630 Da
Isoelectric point
9,68239
Sequence
MAWGGVTPQAVLQGLHIPVTKANVQDLLAWQRAEGGGATNNPFNTTQMASGAGSYNSVGVRNYTSAQQGLQATLQTLTNGRYSGILKALRSGNGSQFASAVGASPWGTSGSLIASVLGTKLSMPSGAGFQHPQGKGVVQAGGTRFDAATFKKQAGAILMQNAAAEENAGAQALAQGQLPGTQTQVPGDSIMQQLEQARQAAMVKVTRSGQVKTGLEGVRGVPQGNDPGSKAVQMALKQIGVPYVWGGENAKGKAGGPGAGFDCSGLVQFAYGALGIHLPRTAAEQGSAGKRVSYNNLKPGDLLVENNGDHVVMYAGNGKVIQAPHTGTSVQMSPMSWFPDSQYYAVRPY
Other Proteins in cluster: phalp2_12235
Total (incl. this protein): 16 Avg length: 330,5 Avg pI: 9,78
Protein ID Length (AA) pI
6Tv9w 349 9,68239
15MrM 376 8,86867
15My8 287 9,46017
1boSk 329 10,02395
2mZCo 340 9,44579
3NS32 348 9,60406
3Qwz4 330 10,22683
4EGGL 346 9,99926
4KsLe 336 9,65622
4XMdO 348 9,58737
5Dm1B 328 9,87522
5GJcs 332 10,03684
5kf2i 316 9,46771
6AjdP 329 9,70760
6DtLP 321 9,54076
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12206
6KgFL
 3 33,1% 341 1.473E-46
2 phalp2_28557
7UTPg
 9 28,4% 285 8.925E-32
3 phalp2_2590
6EE0m
 7 25,6% 308 6.232E-30

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Cellulosimicrobium phage DS1
[NCBI] 		2812903 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MW590223 [NCBI]
CDS location
range 11925 -> 12746
strand +
CDS
GTGCCCAGAGCACTCCCTAACTTCAGCGGCTTGCAGCGGCTTGAGCAGACGATTAAGACTCGGCTTGAGCCGCTGCAACGCTCTATGTCCTTTGGGTCAAATGCGGTTACTAACACGCAGATTCGTAAGGACCCTGGTGTCCAGGCTAGGCAGGCAACTACTAACCCGGGCACCGCTAATGCGCAGTTGACGAGCAACTATCGAACCAAGTTCGACAAGACTCGTGACTTCTCTTCGCGCATTACTCAAATGACGCAGACCGCTGCACAGCAGCGTCGTTTGCAGCAGATGCAGTCTCAGTTGGAAGCGGCTCAGGCTAGAACTATTCAGCCTGTCGCCGCACGTGCGGGGGCTCAGCGTGGTAATAACCAGGCAATGCCTGTCGCTAACAACTACGCTGGACCTATCAACTCGAAGAACCCTATTCGACAGCAGATCGTTAAGGCGGCTCTGTCGTTGCAGGGAACGCCTTACGCATGGGGTGGCGGTGGTTACGGAAGTCGTGGTTCGCGCGGCACCGGCCTCGGTACTCAAAACGTTATTGGCGTCGACTGCTCAGGTCTGACTCAGTATGCCTATGGGTCTGTCGGAATTAAGATTCCGCGACACTCTAATAGTCAGACTGCCTCAGGCTACCGGACGAACATCGGTAACGCTCAGCCGGGCGACCTGGTGGGATGGAATCGAGGGGGCCACGTTGCTATCTACATCGGGAACGGGATGATTATGGAATCACGAAAGCCTGGCACTAGGGCCTCAATCCGACGGCTGGGCGCTAATGAAGGTGTCTACGCTGTTCGTCTACGGTTGCCGGGAGACTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6Tv9w) rather than this protein.
PDB ID
6Tv9w
Method AlphaFoldv2
Resolution 67.63
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50