Protein

Protein accession
A0A6J7WW44 [UniProt]
Representative
4O60Z
Source
UniProt (cluster: phalp2_3617)
Protein name
VanY D-alanyl-D-alanine carboxypeptidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MSKVAWDYIVPVKLPLDLQGITPGKLPDKLLKPAVGGGKLHHLAANAWAAMVAKAKSEGVELKPTSSADTYRDYETQKKGFLTRYVLEDTGTGKTKTFEGKTWYLKKGMATLATPGKSQHNLGLAVDVHSAGEAKRLNWLIANVKLFGFSWEVVPEEPWHLRYVSGDNVPLAVVEFTQQQKAV
Physico‐chemical
properties
protein length:183 AA
molecular weight:20131,0 Da
isoelectric point:9,38
hydropathy:-0,28
Representative Protein Details
Accession
4O60Z
Protein name
4O60Z
Sequence length
75 AA
Molecular weight
8261,32740 Da
Isoelectric point
6,81883
Sequence
MAMLATPGKSNHNLGLAVDVHSASEPKRLNWLIANVKDFGFSWEVVPSEPWHLRLVTGDNPTPAVQAWVDSRKAV
Other Proteins in cluster: phalp2_3617
Total (incl. this protein): 64 Avg length: 101,1 Avg pI: 7,93
Protein ID Length (AA) pI
4O60Z 75 6,81883
15YAa 47 6,76733
1JkYQ 84 5,44986
1NWqP 66 6,63643
1X6so 106 9,09773
1rKUU 184 8,98536
1rUO9 48 6,82491
1uNsw 61 5,19164
1xTXz 125 9,65461
1ycXc 71 8,68223
1yj7L 137 9,19089
2cW9h 100 9,45534
2d18k 100 9,45540
3W2gq 104 9,93750
3jCzy 97 6,93023
424Iw 106 9,09773
499jk 80 6,97462
4A3Zx 91 6,26124
4DWZ9 79 6,81132
4NIS9 69 6,23753
4OM5U 124 9,55152
4OMlV 79 6,23293
4YEna 111 9,88598
4mNLb 64 5,63862
4oVqC 102 8,73452
4zPRP 126 9,51703
4zWxu 93 9,37443
4zXuf 91 6,82508
50fqp 93 9,13422
52Rta 90 6,07196
56KWI 69 5,78208
58UDZ 138 9,57647
58bfh 79 6,23765
58pDE 110 8,97047
58sEO 79 6,80626
59sgt 185 8,94288
5C6QA 106 9,09773
5Hv8p 69 5,81340
5bqb1 79 7,94768
5bs9V 93 9,13422
5uXkZ 79 5,78214
5yOFq 66 6,68008
6A2BV 114 9,43264
6GcLg 102 9,47900
6Kylf 72 6,71026
6LRTv 59 4,96013
6xDPO 138 9,58518
6xORH 138 9,26644
6yVvO 94 9,09818
6ybcO 106 8,92779
6yfdP 69 6,81087
6z653 69 6,43789
6zTj7 99 9,82139
7Y0qG 110 7,66294
82UhW 162 9,07787
8m3OZ 119 8,89233
C8C9 76 5,07285
DybK 115 8,92618
JpSP 135 9,29965
hbKx 183 8,93933
ua5i 106 9,47803
ue6m 69 5,00907
A0A6J5NZ40 195 9,12984
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_20841
6yKUt
 1 58,4% 53 3.620E-18
2 phalp2_461
dTjD
 2 40,0% 45 1.785E-13
3 phalp2_10282
1cVbp
 3 32,7% 61 1.958E-10
4 phalp2_8111
6GeTS
 1 28,1% 64 9.922E-06

Domains

Domains [InterPro]
PET_M15
Representative sequence (used for alignment): 4O60Z (75 AA)
Member sequence: A0A6J7WW44 (183 AA)
1 75 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF02557

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR798301 [NCBI]
CDS location
range 16801 -> 17352
strand +
CDS
ATGAGCAAAGTTGCTTGGGATTATATTGTTCCTGTAAAACTACCCCTTGATTTGCAAGGAATTACGCCTGGAAAACTTCCAGATAAACTGTTAAAGCCAGCCGTAGGCGGTGGAAAACTTCACCATCTCGCTGCAAACGCATGGGCTGCTATGGTGGCTAAGGCTAAGTCTGAGGGAGTGGAACTCAAACCGACTTCCTCCGCAGACACATATAGAGATTATGAGACCCAAAAAAAGGGATTTTTAACCCGTTACGTACTTGAAGACACGGGTACGGGGAAAACCAAGACCTTTGAAGGCAAGACTTGGTATCTCAAAAAAGGTATGGCGACCTTGGCGACACCTGGTAAGAGTCAGCATAACCTTGGTTTGGCAGTTGACGTGCACTCTGCTGGTGAAGCAAAGCGTTTAAATTGGCTTATTGCTAATGTTAAGTTGTTTGGATTTTCGTGGGAAGTTGTTCCTGAAGAACCTTGGCACTTGCGCTATGTATCAGGTGACAATGTTCCTCTAGCGGTGGTAGAGTTTACCCAGCAACAGAAAGCAGTGTAG

Gene Ontology

Description Category Evidence (source)
GO:0004180 carboxypeptidase activity molecular function None (UniProt)
GO:0006508 proteolysis biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4O60Z) rather than this protein.
PDB ID
4O60Z
Method AlphaFoldv2
Resolution 90.56
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50