Protein

Protein accession
A0A6J7WV90 [UniProt]
Representative
4f9gV
Source
UniProt (cluster: phalp2_7319)
Protein name
Endopeptidase, NLPC/P60 domain containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKTAIVLITAIMFWGTGTPPALATNDRTDQAASRSGARTMVGLNALTLAKDYVGTRYCKGGISPRCFDCSGLIKYVYSKQGVKLPGFVSGQMKAATIIPKSSAQPGDLVFFVTKSGYPYHVGIYMGNNEILHSPKPGRKVRVETIWSSRVRFGTIS
Physico‐chemical
properties
protein length:156 AA
molecular weight:16869,5 Da
isoelectric point:10,02
hydropathy:-0,03
Representative Protein Details
Accession
4f9gV
Protein name
4f9gV
Sequence length
200 AA
Molecular weight
21200,48320 Da
Isoelectric point
7,86342
Sequence
MTVNTDTAASLINPLDLDVDTSLTPTSGDDIDMPFGLGGMLSQRVTQSQFKELAGDGGGWGTGTDGGTWNPGGFTSTAAGNGRRQQVIEYAKKFLGTPYVWGGTTPNGFDCSGLVQYVYKKFGVNLPRVSQQQANAGKRTSLNNLELGDLVLFNHGKNGPGHVAFWLGNGQVLEAPRTGLNVRIRKLGKGESVFGVHLNV
Other Proteins in cluster: phalp2_7319
Total (incl. this protein): 3 Avg length: 182,7 Avg pI: 8,20
Protein ID Length (AA) pI
4f9gV 200 7,86342
4wVIO 192 6,72283
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_2894
wl1m
 22 50,5% 186 1.559E-46
2 phalp2_8990
3SsWr
 1 54,6% 130 3.603E-36
3 phalp2_14699
6wXZL
 6 39,0% 123 3.004E-21
4 phalp2_34422
4tFsx
 17 36,8% 160 1.243E-19

Domains

Domains [InterPro]
Disordered region
NLPC_P60
Representative sequence (used for alignment): 4f9gV (200 AA)
Member sequence: A0A6J7WV90 (156 AA)
1 200 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00877

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR798295 [NCBI]
CDS location
range 1568 -> 2038
strand +
CDS
ATGAAAACAGCGATTGTTTTAATAACGGCTATTATGTTTTGGGGAACTGGAACACCTCCAGCCTTAGCAACAAACGATAGGACAGATCAAGCAGCCTCAAGAAGTGGTGCAAGAACAATGGTTGGTCTAAACGCTTTAACCTTGGCTAAAGATTATGTTGGAACAAGGTATTGTAAAGGTGGGATAAGCCCAAGATGCTTTGATTGCTCAGGGCTAATTAAATATGTATACTCAAAGCAAGGAGTAAAGCTTCCTGGATTTGTTAGTGGTCAAATGAAGGCAGCAACTATAATCCCAAAAAGCTCAGCTCAGCCTGGGGACCTTGTATTTTTTGTTACTAAAAGCGGATATCCATATCATGTAGGAATTTACATGGGAAACAATGAAATACTACACTCTCCAAAGCCTGGAAGAAAGGTAAGAGTGGAGACCATTTGGAGTTCTAGAGTCAGGTTTGGAACCATATCTTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4f9gV) rather than this protein.
PDB ID
4f9gV
Method AlphaFoldv2
Resolution 71.14
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50