Protein

Protein accession
A0A6J7WTJ6 [UniProt]
Representative
4emso
Source
UniProt (cluster: phalp2_16101)
Protein name
N-acetylmuramoyl-L-alanine amidase domain
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTTPDALFRRDFRQWKTAEEFRNHVWSYDSNIANWAKAIIMHHTYSPQEYQWRGLSTMTGMMNYYRGLNWTSGPHLFIAPDGIWQMTAINEPGTHAAMWNNKAWGIEMVGYFDHHAWSEKQRTTMYHVAETLLRWRGLQPSKDTVLGHRETGSPKTCPGTMIDMDLVRADLRARFVQDTNP
Physico‐chemical
properties
protein length:181 AA
molecular weight:21193,7 Da
isoelectric point:7,95
hydropathy:-0,67
Representative Protein Details
Accession
4emso
Protein name
4emso
Sequence length
367 AA
Molecular weight
39065,14000 Da
Isoelectric point
9,14118
Sequence
MAFAQDIRHWPTAAALAAHLAQHNPAICQWVDGATLHHTYRPTVAQWRGYASMIGMRDFYVTKGWTAGPHLYIAPDGIWQLTPLNLGGVHAGVCNRTRWGIEVVGDYDAGPWPPALAALVHDTLAALFGWRGLAADALNGHRDCNSPKTCPGRAIQLPVVRAELAARLTSAPAALSSHATIMSAPRCTQAQALAALTRHSTGGYTPADLALAILPAYWSVCTAVGVDPCLAVAQMIHETGNLTSWWAQRPRRNPAGIGVTGVTSATRPIGGAWAQDGAVWREGCSFADWANAAIPAHVGRLLAYATQPSARTAVQRDLVRRAMAVRPLANSVHGRAPTLAWLDGTWAVPGVGYGLQIAQIAEDVRHA
Other Proteins in cluster: phalp2_16101
Total (incl. this protein): 41 Avg length: 387,0 Avg pI: 8,43
Protein ID Length (AA) pI
4emso 367 9,14118
1GXnN 426 8,66747
1LOUn 377 6,30790
1LY1Y 371 9,09734
1X3Cz 319 8,52680
1YdhE 406 9,85730
1ftW6 453 8,40547
1osLk 353 7,72757
2Tsyr 404 9,08136
2w7Ac 376 8,92708
35cDi 407 9,31486
3OTKP 384 9,24253
3UY5p 388 8,54014
3XpL2 384 8,88292
3hfTR 369 9,06150
3lxaU 370 8,95248
42ifD 384 9,07510
4BCXI 481 8,89620
4C4Kw 355 8,48070
4C5ne 462 7,29889
4F7cH 423 9,42001
4N48i 344 8,81001
4SRrN 347 8,95306
4eT6m 359 9,21906
4ljrh 384 8,12883
4qGOc 357 7,84324
4qHBi 416 9,46978
4qHcj 390 6,70350
4qHjK 416 9,47016
4r4kz 377 8,25171
4v5l3 382 9,01779
5JzxW 433 8,40431
5k3e8 347 9,38577
6Rhg1 529 6,06537
6Vxhn 368 6,89755
6wTzv 370 8,33455
7JnLw 456 6,50633
8eGx5 390 7,24654
fPle 359 6,66729
l2PI 401 9,34716
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27574
5CQSE
 6 29,3% 388 3.413E-67
2 phalp2_17390
4KHe6
 1 32,1% 255 3.443E-44
3 phalp2_3828
6v3ib
 489 25,7% 307 3.729E-27
4 phalp2_4721
4Qzp5
 7 24,7% 303 3.406E-20
5 phalp2_5406
2FYAK
 2 22,1% 338 1.623E-12

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 4emso (367 AA)
Member sequence: A0A6J7WTJ6 (181 AA)
1 367 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796224 [NCBI]
CDS location
range 9702 -> 10247
strand -
CDS
ATGACCACACCAGATGCACTATTTCGACGTGATTTCAGGCAGTGGAAAACAGCAGAAGAATTTCGGAATCACGTGTGGTCATATGATAGCAACATTGCCAATTGGGCCAAGGCAATCATCATGCACCACACGTATTCGCCACAGGAATACCAGTGGCGTGGTTTGTCTACCATGACTGGCATGATGAATTATTACCGTGGCCTTAATTGGACCAGTGGGCCACACCTATTCATTGCACCAGATGGTATCTGGCAAATGACGGCCATCAACGAGCCAGGCACACACGCGGCCATGTGGAATAATAAAGCATGGGGAATAGAAATGGTTGGCTATTTCGATCATCATGCATGGTCAGAAAAACAACGAACCACCATGTACCACGTGGCCGAAACGTTATTACGCTGGCGTGGCCTGCAGCCATCAAAAGATACCGTGCTAGGCCACAGGGAAACAGGCAGCCCAAAAACATGCCCTGGCACTATGATAGATATGGATCTCGTGCGTGCTGATTTGCGTGCACGATTTGTACAGGATACGAATCCATGA
CDS Source ID
[NCBI]
CDS Source
LR798264 [NCBI]
CDS location
range 15613 -> 16158
strand +
CDS
ATGACCACACCAGATGCACTATTTCGACGTGATTTCAGGCAGTGGAAAACAGCAGAAGAATTTCGGAATCACGTGTGGTCATATGATAGCAACATTGCCAATTGGGCCAAGGCAATCATCATGCACCACACGTATTCGCCACAGGAATACCAGTGGCGTGGTTTGTCTACCATGACTGGCATGATGAATTATTACCGTGGCCTTAATTGGACCAGTGGGCCACACCTATTCATTGCACCAGATGGTATCTGGCAAATGACGGCCATCAACGAGCCAGGCACACACGCGGCCATGTGGAATAATAAAGCATGGGGAATAGAAATGGTTGGCTATTTCGATCATCATGCATGGTCAGAAAAACAACGAACCACCATGTACCACGTGGCCGAAACGTTATTACGCTGGCGTGGCCTGCAGCCATCAAAAGATACCGTGCTAGGCCACAGGGAAACAGGCAGCCCAAAAACATGCCCTGGCACTATGATAGATATGGATCTCGTGCGTGCTGATTTGCGTGCACGATTTGTACAGGATACGAATCCATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4emso) rather than this protein.
PDB ID
4emso
Method AlphaFoldv2
Resolution 94.74
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50