Protein

Protein accession
A0A6J5SNY4 [UniProt]
Representative
J8O2
Source
UniProt (cluster: phalp2_37034)
Protein name
TIGR02594, TIGR02594 family protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 83% (predicted by ML model)
Protein sequence
MVAIATGEIGYIEGPKDNETKYGAFTKHNFLPWCGSFLMWCAHKAGVTIPSVVSVIEGEAKFKELGRSHNKPQVGDLAFFNFTHGTLPQHVGLVVAINSTGGITCIEGNTSAKNQSNGGQVEKKPRAPMFVTSYGRPSYTVLKGTPKEKEVS
Physico‐chemical
properties
protein length:152 AA
molecular weight:16372,5 Da
isoelectric point:8,99
hydropathy:-0,25
Representative Protein Details
Accession
J8O2
Protein name
J8O2
Sequence length
196 AA
Molecular weight
20918,68140 Da
Isoelectric point
6,13261
Sequence
MGQRADFIAVAKGELDVIEGPKDNETKYGAFTKANFLPWCGSFVNWCANEVGLKIPNVVSTVAGATAFIKKGQWEKVNEATPLPGDIVFFDFPNDGVDRISHVGIVVKDNGDGTVTCIEGNTSPDKKGDQGEQMFDKEKLKQIGLSYLRAAAASVVALYTAGQHDPKVLASAFVAGLIGPIMKALDKSAPQFGLKK
Other Proteins in cluster: phalp2_37034
Total (incl. this protein): 142 Avg length: 169,1 Avg pI: 9,09
Protein ID Length (AA) pI
J8O2 196 6,13261
16n0m 170 9,24859
17Uqi 170 9,30055
185zI 170 9,22377
18prQ 169 9,08264
19MQj 169 9,14170
1LJHo 170 9,24091
1chZh 170 9,22377
1ciGY 170 9,22377
1ey1M 170 9,11243
1zjSK 170 9,24111
1zqew 170 9,22357
21bVz 169 9,08264
24xf3 171 9,30151
24ybd 170 9,30029
2RXdy 169 9,06865
2cZ22 170 9,09728
2jih2 170 9,09728
30h4V 170 9,09728
30kYT 170 9,08451
31Kht 170 9,09728
31OyA 170 9,09728
34wL2 164 9,09966
35OPl 170 9,05189
36K8o 171 9,11243
38byc 170 9,31808
38f8C 170 9,21152
38fnD 170 9,24111
38hw6 170 9,24111
38lZM 170 9,43432
38nDt 170 9,33684
38ntJ 170 9,33704
3VOa8 169 9,17451
3boUF 171 9,11243
41K8y 169 9,14170
46FPi 169 8,95242
46L84 169 9,15775
46RPC 160 8,95738
46WJU 170 9,11262
47DwI 170 9,09728
47LTT 170 9,33684
47yfy 139 9,32260
484DD 169 8,93978
48DQk 169 9,22357
48VOL 169 9,06865
48f6k 169 8,94152
494af 170 9,20713
498si 169 9,14150
49BHe 169 9,02991
49CPU 166 9,08264
49F8z 170 8,88183
49TJn 170 8,95255
49a5P 170 9,09728
49cAY 170 9,13686
49cfT 170 9,03842
49mV7 170 9,11262
49taW 170 9,05189
4CiGz 170 9,48654
4OuNX 170 9,24111
4RCfQ 170 9,22377
4RwjI 170 9,17451
4V6Rp 169 9,23756
4aJZs 170 9,08264
4aNf7 170 9,24111
4aoY0 170 9,08264
4axfQ 169 9,08264
4axpF 170 9,20713
4b4je 170 9,12835
4b65U 169 8,93978
4bLFP 125 4,69288
4bMmE 170 9,24143
4bW6d 170 9,08264
4bZBY 170 9,11269
4buk5 170 9,22357
4bv4A 170 9,20713
4m9xH 171 9,26328
4n6b0 169 9,14170
4zowF 170 9,11243
54lq6 170 9,24091
54vxh 170 9,46887
55sSj 170 9,25967
5C4Zl 170 9,16645
5Dy8x 170 9,26335
5a5qv 169 9,15775
5aOre 170 9,09728
5eHZM 169 9,15775
5ibgB 170 9,11243
5jIhp 169 9,15775
5jTZ6 169 9,02991
5kVNV 169 9,15775
5laE0 169 9,26309
5nYek 170 9,20713
5uvBd 169 9,15775
5wSlE 170 9,06865
6Apwn 170 9,09728
6AyR1 169 9,08264
6GipE 169 9,02991
6GwNT 169 9,17471
6II0n 169 9,01521
6KVwd 169 9,24601
6M5Ju 170 9,09728
6MnrZ 169 9,08264
6xsgp 169 9,15775
6xxKb 170 9,20713
6ybQs 170 9,22357
6yzXE 170 9,31834
7Vygw 170 9,17490
7XJml 170 9,22377
7XN3I 170 9,11269
85CJM 169 9,02991
87r6p 170 9,09728
87uIi 170 9,22377
87wGN 170 9,08264
883jJ 170 9,11262
88f6x 166 8,96570
8msWX 170 9,11262
8mwQ2 170 9,09709
Cfdd 170 9,12848
FOPt 169 9,00096
FXw5 170 9,03823
FYlJ 170 9,30035
FdXM 170 8,95235
Fo2L 169 8,93978
Fytu 170 9,08264
G0t7 170 9,20713
GgRZ 169 9,00096
GnIS 170 9,09728
GyFc 170 9,09728
IPLC 170 9,09728
KTAx 170 9,20694
Q7sB 170 9,09734
QxVg 170 9,34168
SxZN 170 8,73071
THZC 169 9,23776
U720 170 9,09728
UcDb 169 9,06865
hWln 170 9,19127
uIsn 170 8,95235
A0A6J5MU15 167 8,86996
A0A6J5N7V8 167 9,01534
A0A6J5RKL6 179 8,83122
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12059
59yJo
 3039 71,9% 139 7.512E-70
2 phalp2_17860
jW87
 92 44,2% 138 2.747E-32
3 phalp2_32427
U2OC
 884 44,2% 131 6.646E-26
4 phalp2_24157
2dFjl
 298 38,3% 146 1.241E-25
5 phalp2_18705
oeYw
 31 33,7% 169 9.177E-21
6 phalp2_16018
3yVVm
 206 34,8% 155 3.804E-19
7 phalp2_15515
8mtdC
 92 32,1% 146 1.884E-14
8 phalp2_552
ESm7
 27 31,7% 170 2.562E-14
9 phalp2_31351
2tjAl
 675 29,4% 173 4.737E-14
10 phalp2_26777
3lq1V
 3 37,1% 121 8.754E-14

Domains

Domains [InterPro]
CHAP
Unannotated
Representative sequence (used for alignment): J8O2 (196 AA)
Member sequence: A0A6J5SNY4 (152 AA)
1 196 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796906 [NCBI]
CDS location
range 16253 -> 16711
strand -
CDS
ATGGTGGCTATTGCCACTGGTGAAATAGGTTATATAGAAGGCCCGAAAGATAACGAGACAAAGTACGGGGCTTTTACTAAACACAACTTTCTGCCTTGGTGCGGCTCTTTTCTTATGTGGTGCGCCCATAAAGCAGGGGTAACTATTCCCAGCGTTGTAAGTGTCATCGAAGGCGAAGCAAAGTTTAAGGAATTAGGGCGCAGCCACAATAAACCACAAGTAGGCGATCTAGCCTTCTTTAACTTTACCCATGGCACACTGCCCCAGCATGTCGGACTAGTTGTAGCCATTAACTCAACAGGTGGCATTACTTGTATTGAAGGCAACACCAGTGCCAAGAATCAAAGTAATGGTGGCCAAGTAGAAAAGAAGCCACGCGCACCCATGTTTGTCACATCGTATGGACGGCCTAGTTACACTGTTCTCAAGGGCACACCAAAAGAAAAGGAAGTGTCCTAA
CDS Source ID
[NCBI]
CDS Source
LR797203 [NCBI]
CDS location
range 1145 -> 1603
strand -
CDS
ATGGTGGCTATTGCCACTGGTGAAATAGGTTATATAGAAGGCCCGAAAGATAACGAGACAAAGTACGGGGCTTTTACTAAACACAACTTTCTGCCTTGGTGCGGCTCTTTTCTTATGTGGTGCGCCCATAAAGCAGGGGTAACTATTCCCAGCGTTGTAAGTGTCATCGAAGGCGAAGCAAAGTTTAAGGAATTAGGGCGCAGCCACAATAAACCACAAGTAGGCGATCTAGCCTTCTTTAACTTTACCCATGGCACACTGCCCCAGCATGTCGGACTAGTTGTAGCCATTAACTCAACAGGTGGCATTACTTGTATTGAAGGCAACACCAGTGCCAAGAATCAAAGTAATGGTGGCCAAGTAGAAAAGAAGCCACGCGCACCCATGTTTGTCACATCGTATGGACGGCCTAGTTACACTGTTCTCAAGGGCACACCAAAAGAAAAGGAAGTGTCCTAA
CDS Source ID
[NCBI]
CDS Source
LR797440 [NCBI]
CDS location
range 13424 -> 13882
strand +
CDS
ATGGTGGCTATTGCCACTGGTGAAATAGGTTATATAGAAGGCCCGAAAGATAACGAGACAAAGTACGGGGCTTTTACTAAACACAACTTTCTGCCTTGGTGCGGCTCTTTTCTTATGTGGTGCGCCCATAAAGCAGGGGTAACTATTCCCAGCGTTGTAAGTGTCATCGAAGGCGAAGCAAAGTTTAAGGAATTAGGGCGCAGCCACAATAAACCACAAGTAGGCGATCTAGCCTTCTTTAACTTTACCCATGGCACACTGCCCCAGCATGTCGGACTAGTTGTAGCCATTAACTCAACAGGTGGCATTACTTGTATTGAAGGCAACACCAGTGCCAAGAATCAAAGTAATGGTGGCCAAGTAGAAAAGAAGCCACGCGCACCCATGTTTGTCACATCGTATGGACGGCCTAGTTACACTGTTCTCAAGGGCACACCAAAAGAAAAGGAAGTGTCCTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (J8O2) rather than this protein.
PDB ID
J8O2
Method AlphaFoldv2
Resolution 80.47
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50