Protein

Protein accession
A0A6J5RU10 [UniProt]
Representative
7gDKs
Source
UniProt (cluster: phalp2_36860)
Protein name
Peptidoglycan binding-like
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSANFDTGIADRLRAAGLVVVEIAGWQTRGVGGAFEPIGSLDHHTAGAATGNAPSLGVCINGRAGLPGPLANVLVGRDGTHYVIAAGRCNHAGAGRWLSITSGNGQMYSVERENVGTGAEPWTVEQTLRAGQCHAALLGARGNADNVCRHAEYATPKGRKTDTANINGNDLRQIVRAILAAPVAPPAPEAGTPGPEWVLLAKLNEVAASRPVLSEGSTGVFVNDVQTALNVILAKGSTKPLLAVDGHYGKATANLVRLYQKSRGLPADGVVGRVTWVAILADRLKLGR
Physico‐chemical
properties
protein length:288 AA
molecular weight:29763,4 Da
isoelectric point:9,32
hydropathy:-0,03
Representative Protein Details
Accession
7gDKs
Protein name
7gDKs
Sequence length
259 AA
Molecular weight
26510,07370 Da
Isoelectric point
8,84295
Sequence
MPNAFWLADVLRAAGLKVAEVDGWKTRGHGELGTVRMVMLHHTAGPQTGNMPSLATVTKGRPDLAGPLCNVALGRDGTCYVVAAGLAYHAGPGAWQGITAGNSSSIGVEAENTGLGESWPEVQLDAYARLCAAVLSHVGAAPIMAVAHREWALPKGRKIDPAGIDMAAFRARVAGIMNGAPVRPAIPAKDITGRPTLRRGAKGDDVKVLQAAIGITADGDFGPVTEAGLRAWQRAHGLVADGIAGPGTWAAIDGAKAAA
Other Proteins in cluster: phalp2_36860
Total (incl. this protein): 246 Avg length: 269,6 Avg pI: 7,26
Protein ID Length (AA) pI
7gDKs 259 8,84295
11EFj 295 5,08956
156zd 274 9,56016
15IrB 202 8,83638
16MKc 318 4,80729
16OR9 186 7,72785
1886E 307 6,89027
18Qyw 262 5,17112
1FBDj 329 5,13969
1GB77 226 6,59170
1Igpb 279 9,02791
1IvzY 190 6,82093
1JthU 245 8,29568
1KUht 243 7,01441
1LS6z 238 6,60199
1QqwB 271 7,70460
1ZqTg 253 5,58946
1cOKN 193 6,42573
1cWwb 243 8,31018
1dcoI 193 6,53582
1e2IZ 239 7,11155
1eGm9 226 7,94323
1elko 238 6,33177
1elyO 223 6,23463
1fBQH 256 7,17293
1fbfk 310 4,71448
1jqHG 289 10,10750
1nN3t 250 6,44119
1oA23 274 10,65161
1oSMe 189 6,34189
1onnO 319 4,71084
1oyyO 212 6,46444
1pRAF 266 5,82261
1pxeO 361 9,38532
1qQ5j 283 5,28923
1rxvW 283 9,61374
1slhd 281 9,22170
1sonu 274 5,79163
28xQ7 270 9,86213
2Dc2d 255 8,55671
2KPJ 257 9,83054
2Qmkl 314 7,68937
2QxXo 287 5,99404
2T9OM 365 9,77484
2XNz9 266 6,20002
2YpRV 334 5,46174
2aeWM 283 5,24257
2cSDh 259 9,22963
2eklo 266 8,88711
2kKrm 304 5,90184
2kNTa 304 5,12184
2rJ3e 300 9,47358
32Za3 238 8,04193
34CrV 280 6,43982
35Fkt 278 6,42527
38Y4V 305 10,12684
3OKmN 284 5,79152
3VCPO 306 6,83036
3XhUt 274 5,15009
3Ximd 242 7,16009
3Xiy1 273 5,74826
3gmA4 249 5,06671
4CPni 263 9,63192
4CrdJ 276 6,70151
4E2Lt 255 7,06647
4EKoQ 297 6,74738
4EZl0 259 4,87050
4Fazp 270 6,50559
4Fgo6 260 9,34722
4HB5m 249 5,49834
4IkLr 293 4,74318
4Jkk9 285 5,52693
4M8Cv 292 6,96780
4M8mw 274 9,06885
4M92A 267 5,63396
4MX0p 218 9,44496
4NEut 197 9,89823
4QwE4 247 7,83473
4TnBG 304 5,69074
4Uz1X 244 7,81055
4Yk92 306 6,16154
4ctw3 291 6,82911
4eMhm 288 9,81874
4f4zz 273 9,55210
4f67S 371 9,70090
4gOHh 267 5,81198
4jMPC 273 6,11317
4kT5A 328 9,55068
4kTBV 270 7,80817
4kVFx 249 7,76809
4kVWZ 328 9,53147
4kyfx 305 7,79289
4mTS2 296 8,79105
4n6kh 300 9,03913
4nP1t 259 9,00606
4nP8D 222 9,44135
4nPJw 259 9,25033
4nRhN 260 9,11888
4nRuX 256 9,54037
4nS5C 257 9,29720
4nw01 246 9,02411
4pML4 282 9,18057
4qMHI 245 6,64672
4qNPi 255 9,33904
4wYMp 245 8,26905
51Ycp 245 8,26905
53p9R 266 7,79450
57AYQ 239 8,82677
59TRq 266 7,79437
5B23w 295 9,57692
5BkQB 225 7,02043
5DJwP 290 7,00634
5H7wR 278 5,41047
5HfiH 254 9,29939
5Isrf 300 7,14599
5JBhF 185 9,18044
5JN7B 239 4,88346
5JNh8 257 4,86334
5JbQd 272 8,37027
5TZ 253 8,80614
5a2qj 245 8,25403
5bAgX 254 9,21622
5bAtG 281 8,58985
5cwEG 225 9,75041
5e6fM 276 4,75398
5k8sE 251 5,87285
5kwHK 274 9,69116
5tklP 248 9,50459
5whGf 297 9,72082
5yaBe 303 6,05298
5yaT7 197 6,78029
6Dpln 259 6,53969
6IcS8 263 5,35221
6MNxX 260 6,28835
6MODh 319 4,67429
6MziM 267 9,82919
6QKaq 265 5,38046
6RRpP 263 8,78042
6RrNI 272 5,96738
6RxcE 323 10,33146
6SMMp 304 9,65938
6TdmN 281 6,71481
6V08a 269 4,67503
6WzDz 239 5,65965
6ytYX 239 8,82690
71Pj1 259 7,14872
71xZR 319 4,77632
72Cbv 257 5,71928
72awu 292 4,50196
72u0G 332 5,99585
75fJz 357 9,74693
75u4j 257 5,08262
76YBy 257 5,27946
76nhI 285 5,68767
79IYd 270 6,18365
79J0W 265 5,98011
7AVsT 270 6,55492
7YPgJ 251 8,82458
7Zmxr 238 6,74880
7b6df 257 5,55382
7bf2s 268 5,92248
7cMz5 275 5,27718
7cuME 323 8,74915
7dRvX 259 6,28931
7e0wK 359 8,30535
7hlw9 257 6,78995
7k0JC 355 5,71575
7k8hK 329 9,40815
7kHtf 250 6,23520
7lGAm 257 5,19920
7lGDP 257 5,92708
7lGGO 257 5,04875
7lGK6 270 6,07952
7lGO5 273 5,48032
7lGqa 274 5,68557
7m5zj 259 5,48180
7mjMW 279 5,38302
7o3Co 355 5,73002
7of4A 260 6,44738
7pFlq 296 9,44960
7qr7U 275 5,12696
7qrcT 276 5,17817
7rD1P 247 6,75863
7rV5l 313 10,08120
7reqX 249 4,64996
7sFUr 323 9,73120
7sdYm 274 7,70142
7se06 274 6,37690
7sspM 259 9,40151
7tN2w 243 6,59119
7ubCS 233 5,30304
7uk4F 224 7,33055
7ukiv 362 7,77389
7umxy 267 5,23990
7unAc 286 7,11729
7vYMM 261 5,11201
7wJ3T 259 9,47906
7wek0 294 10,86139
7x2aj 248 6,25083
7x2ff 224 8,71472
7xuCH 245 5,73297
7yeVg 241 6,75051
7z9Y1 250 5,89610
7zeYz 275 5,85171
84G3e 300 8,94404
85Djc 302 7,74678
8826M 274 6,15631
8MKfn 283 5,39927
8aM1o 261 5,46765
8ap8C 305 6,74562
8bEyC 194 5,47635
8dMHx 243 6,25487
8eleF 252 6,70844
8ftcw 235 7,74496
8iB4r 237 6,79109
8iHQQ 265 8,69622
8iT8j 305 6,74562
8ionV 236 8,58469
8jnJ7 271 6,62773
8jtyD 247 8,99916
8kYfy 244 6,58562
8msOr 175 9,78973
8nD7G 246 6,99844
8oZU2 247 5,64271
8qyyy 233 6,05082
8sFWx 281 9,02359
8sIJi 246 8,82967
8tfQX 345 7,18913
CFTr 336 6,01984
Cb0t 244 8,84031
D0bu 339 8,96376
OVKJ 250 6,44113
QOKC 275 6,46114
QOVk 250 5,53813
TKyQ 255 9,21622
bJQQ 266 8,42133
jFcf 253 7,69318
jqMe 275 9,98191
kaBf 308 6,19365
lKz5 271 6,62643
teCr 271 10,30638
txPN 327 4,57306
ujUV 267 5,74929
xM9q 271 6,58618
zVMj 287 8,80221
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27801
7zeFm
 19 42,2% 246 4.218E-72
2 phalp2_32562
1EaZA
 16 51,0% 200 5.794E-69
3 phalp2_39672
6W6Kj
 11 54,8% 177 4.235E-66
4 phalp2_37674
4urEs
 29 39,8% 221 2.035E-65
5 phalp2_22551
1qQEX
 38 54,2% 188 5.219E-65
6 phalp2_12024
7Qd9Y
 81 37,0% 197 1.338E-64
7 phalp2_12497
QM59
 22 49,4% 184 7.915E-63
8 phalp2_39896
1eFLE
 1 50,9% 159 3.416E-61
9 phalp2_22739
8doto
 1 38,8% 265 2.244E-60
10 phalp2_2737
7uk55
 6 49,7% 195 2.016E-59

Domains

Domains [InterPro]
Ami2
PG_1
Representative sequence (used for alignment): 7gDKs (259 AA)
Member sequence: A0A6J5RU10 (288 AA)
1 259 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR797310 [NCBI]
CDS location
range 9095 -> 9961
strand +
CDS
ATGAGCGCCAACTTCGATACGGGCATTGCCGATCGCCTGCGTGCTGCCGGGCTCGTCGTCGTCGAGATCGCCGGATGGCAGACTCGTGGCGTGGGCGGCGCCTTCGAGCCGATCGGCTCTCTCGATCATCACACGGCGGGCGCCGCCACCGGCAACGCCCCGAGCCTCGGGGTCTGCATCAACGGCCGGGCCGGGCTCCCCGGTCCCCTGGCCAACGTCCTCGTGGGCCGGGACGGCACGCACTACGTCATCGCTGCCGGTCGGTGCAATCACGCAGGCGCCGGGCGCTGGCTCAGCATCACGTCCGGCAACGGGCAGATGTACTCCGTCGAGCGTGAGAACGTCGGGACGGGCGCAGAGCCGTGGACCGTCGAGCAGACGCTTCGTGCGGGCCAGTGCCACGCCGCCCTCCTCGGTGCCCGAGGGAACGCCGACAACGTGTGTCGTCACGCCGAGTACGCCACGCCCAAGGGGCGCAAGACGGACACGGCGAACATCAACGGCAACGACCTGCGTCAGATCGTGCGTGCGATCCTGGCCGCACCCGTGGCGCCGCCTGCGCCCGAGGCTGGCACGCCCGGCCCCGAGTGGGTCCTTCTCGCCAAGCTGAACGAGGTGGCGGCATCCCGCCCCGTGCTCAGCGAGGGCAGCACGGGCGTCTTCGTGAACGACGTGCAGACCGCCCTGAACGTGATTCTCGCCAAGGGCAGCACGAAGCCCCTGCTCGCGGTCGACGGGCACTACGGCAAGGCGACGGCGAACCTCGTCCGCCTGTACCAGAAGTCCCGAGGTCTGCCCGCCGATGGCGTGGTCGGCCGTGTGACGTGGGTCGCCATCCTGGCGGACCGCCTGAAGCTCGGAAGGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7gDKs) rather than this protein.
PDB ID
7gDKs
Method AlphaFoldv2
Resolution 94.03
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50