Protein

Protein accession
A0A6J5RM51 [UniProt]
Representative
4zLyc
Source
UniProt (cluster: phalp2_23108)
Protein name
N-acetylmuramoyl-L-alanine amidase domain containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTYYLLDHPPASPQFYPSRANPATWAVSVHTSEGSTGPGAALALAQFITRRTDPGSYAVVVDSETTIEMVPPDYTTYSVAASGYNSRTWSICLAGRTAELSPDDPNTLAMIDRAGTAIFELWATQGVNIPAALNWIGTDALTAAGLFCHGDVQPWDRTDAWSLHPDRSALDTLLVQAVARHLPHPPNPPGDEMNRYLIRGNNAGEVYLADAGLGWKWHIPAGQIANIVYALGVGGGQIITPPGANVIIIEGVNVWVADQAFVDAIPRTK
Physico‐chemical
properties
protein length:269 AA
molecular weight:28784,0 Da
isoelectric point:4,87
hydropathy:-0,04
Representative Protein Details
Accession
4zLyc
Protein name
4zLyc
Sequence length
207 AA
Molecular weight
22722,40910 Da
Isoelectric point
4,65264
Sequence
VDSEETIVMVPPDYTTFSVAASGYNSRTWHICLTGRSADLDPDDPNTQAMIRRAGEAIRNLWALLGIDVNAAARWIGTDALSTVGLFCHGDVQPWDRSDAWSKHPDRAALDQQLINAIRPPIPPTPLDDEMKRYLLKGDKQGEIYLCDAGLGWKWHIPSGQMGNVVWVITQSSGGQMLIPAGANTIVWEGQTVWVADQAFVDAIPTL
Other Proteins in cluster: phalp2_23108
Total (incl. this protein): 8 Avg length: 234,9 Avg pI: 5,49
Protein ID Length (AA) pI
4zLyc 207 4,65264
18ATK 274 5,56905
1il0d 256 5,20255
4bhPq 266 4,90898
4oYaS 162 5,60077
5z6h6 190 7,92711
6SXgz 255 5,15270
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_33323
6xhU7
 66 67,8% 168 8.052E-69
2 phalp2_7699
6IwWh
 11 37,8% 169 6.493E-39
3 phalp2_14382
4phRt
 2 25,5% 172 4.471E-12

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 4zLyc (207 AA)
Member sequence: A0A6J5RM51 (269 AA)
1 207 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796843 [NCBI]
CDS location
range 10501 -> 11310
strand +
CDS
GTGACCTACTACCTCCTGGACCATCCCCCAGCGTCGCCACAGTTCTACCCGTCGAGGGCGAACCCGGCGACGTGGGCGGTATCGGTCCACACCTCCGAAGGATCTACCGGACCGGGCGCCGCTCTCGCTCTGGCTCAGTTCATTACGAGACGCACCGACCCGGGGTCCTATGCGGTGGTCGTGGACAGTGAAACGACGATCGAAATGGTCCCGCCGGACTACACGACCTACTCAGTCGCCGCGTCTGGATACAACTCACGAACCTGGTCTATCTGTCTCGCCGGACGCACCGCCGAACTCTCCCCCGACGATCCCAACACCCTCGCCATGATCGACCGGGCCGGCACCGCCATCTTCGAACTATGGGCGACACAAGGCGTCAACATTCCCGCCGCCCTCAACTGGATCGGAACCGACGCCCTCACCGCCGCCGGTCTCTTCTGCCACGGCGACGTCCAGCCCTGGGACCGAACTGACGCCTGGAGCCTCCACCCCGACAGAAGCGCCCTAGACACCCTCCTCGTCCAAGCAGTCGCCCGACACCTACCTCACCCCCCGAATCCCCCAGGAGACGAAATGAACCGCTACCTCATAAGAGGAAACAACGCCGGAGAGGTCTACCTCGCAGACGCGGGACTCGGCTGGAAATGGCACATCCCCGCCGGTCAAATCGCAAACATCGTCTACGCCCTCGGAGTCGGAGGCGGCCAAATCATCACACCACCCGGAGCAAACGTCATCATCATCGAAGGCGTGAACGTATGGGTAGCCGATCAGGCGTTCGTCGACGCGATCCCCCGGACGAAATGA
CDS Source ID
[NCBI]
CDS Source
LR797221 [NCBI]
CDS location
range 9979 -> 10788
strand +
CDS
GTGACCTACTACCTCCTGGACCATCCCCCAGCGTCGCCACAGTTCTACCCGTCGAGGGCGAACCCGGCGACGTGGGCGGTATCGGTCCACACCTCCGAAGGATCTACCGGACCGGGCGCCGCTCTCGCTCTGGCTCAGTTCATTACGAGACGCACCGACCCGGGGTCCTATGCGGTGGTCGTGGACAGTGAAACGACGATCGAAATGGTCCCGCCGGACTACACGACCTACTCAGTCGCCGCGTCTGGATACAACTCACGAACCTGGTCTATCTGTCTCGCCGGACGCACCGCCGAACTCTCCCCCGACGATCCCAACACCCTCGCCATGATCGACCGGGCCGGCACCGCCATCTTCGAACTATGGGCGACACAAGGCGTCAACATTCCCGCCGCCCTCAACTGGATCGGAACCGACGCCCTCACCGCCGCCGGTCTCTTCTGCCACGGCGACGTCCAGCCCTGGGACCGAACTGACGCCTGGAGCCTCCACCCCGACAGAAGCGCCCTAGACACCCTCCTCGTCCAAGCAGTCGCCCGACACCTACCTCACCCCCCGAATCCCCCAGGAGACGAAATGAACCGCTACCTCATAAGAGGAAACAACGCCGGAGAGGTCTACCTCGCAGACGCGGGACTCGGCTGGAAATGGCACATCCCCGCCGGTCAAATCGCAAACATCGTCTACGCCCTCGGAGTCGGAGGCGGCCAAATCATCACACCACCCGGAGCAAACGTCATCATCATCGAAGGCGTGAACGTATGGGTAGCCGATCAGGCGTTCGTCGACGCGATCCCCCGGACGAAATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4zLyc) rather than this protein.
PDB ID
4zLyc
Method AlphaFoldv2
Resolution 79.51
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50