Protein

Protein accession
A0A6J5RGB1 [UniProt]
Representative
5BsWX
Source
UniProt (cluster: phalp2_20773)
Protein name
N-acetylmuramoyl-L-alanine amidase domain
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRVSGVPFDQGKHPQGALIPTAVVMHRTYGTLNGDGFKSAYSIGKNGRSGLGIGFHFLVGKNEGQWVQFYDTTVKSAHAKGANSWAIGIEFDGVNEGPLTDWQVRAGAAICRAISEAHGIPLTYWDGPRQRVTGYLGHASVPTSTHTDRLTREDWDRIVALAQVAVPVQPEPQPDGSGVDLAAIAAGIAEASKQVIKQGSKGDAVKWAQALLNNKLENTNLSVDGNFGPASAAATRIFQRNVKRFFRLNDSQMKVDGIIGPTTWFWLTR
Physico‐chemical
properties
protein length:269 AA
molecular weight:29037,4 Da
isoelectric point:9,35
hydropathy:-0,28
Representative Protein Details
Accession
5BsWX
Protein name
5BsWX
Sequence length
260 AA
Molecular weight
27961,55730 Da
Isoelectric point
9,23698
Sequence
VVLHRTYGSLTKDGYKGAYNIGKNGRAGVGIGFHFLVGKNEGQWVEFYDMLTKCAHAKGANTWAIGVEFDGVNEGPLTDWQIRAGAWILAGINNAIGIPIDRYTIGGPRRKINGPLPHSLVPGSNHTDLVTEADYQKMRALIPSQQCKCPAPGPAVDVAEYVRRRRALAQDYMNSGLGTLPTLSLLSPKSHAMGVALMQSAINLVSGRGLKVDGQFGPATRDAVRDLDRFTGVRNDDGVFEDSSRFVLTLAVKAIADGKA
Other Proteins in cluster: phalp2_20773
Total (incl. this protein): 6 Avg length: 267,2 Avg pI: 9,16
Protein ID Length (AA) pI
5BsWX 260 9,23698
36Brv 277 8,95654
36vJ6 277 9,35573
36zFR 239 9,23621
7ZRJy 281 8,80756
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_19335
8iBfU
 4 48,0% 156 1.039E-47
2 phalp2_22201
6VaYI
 26 24,0% 220 1.010E-09
3 phalp2_184
5Dm5y
 192 21,7% 221 2.590E-07
4 phalp2_13866
7ukRg
 1 25,8% 244 3.475E-04
5 phalp2_36904
7xR8d
 63 20,2% 277 6.156E-04

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 5BsWX (260 AA)
Member sequence: A0A6J5RGB1 (269 AA)
1 260 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR797224 [NCBI]
CDS location
range 8752 -> 9561
strand -
CDS
ATGAGAGTTTCAGGAGTCCCATTCGACCAAGGGAAGCATCCACAAGGAGCTTTGATCCCGACAGCGGTTGTCATGCATCGAACCTACGGGACACTCAACGGTGACGGATTCAAGAGTGCCTACAGCATCGGCAAAAATGGCCGTAGCGGTCTTGGCATCGGCTTCCACTTTCTGGTCGGCAAGAACGAGGGGCAGTGGGTCCAATTTTACGACACCACGGTCAAGTCGGCTCACGCTAAGGGCGCTAACTCATGGGCAATCGGAATTGAATTCGACGGGGTGAATGAGGGACCGCTGACTGACTGGCAGGTTCGTGCCGGAGCGGCAATCTGTAGGGCGATCTCAGAGGCCCACGGTATCCCGCTCACCTACTGGGACGGCCCACGCCAACGGGTGACCGGATACCTTGGCCACGCTTCAGTCCCAACCTCAACACACACAGACAGGCTGACCCGTGAAGACTGGGACCGGATAGTCGCACTCGCTCAGGTAGCTGTGCCAGTACAACCTGAGCCTCAGCCAGACGGATCTGGCGTGGATCTCGCTGCGATAGCTGCCGGGATAGCAGAGGCTTCAAAGCAAGTGATCAAGCAAGGGTCAAAGGGCGATGCGGTGAAGTGGGCACAGGCCCTGCTGAACAACAAGCTCGAAAACACCAACTTGTCTGTCGACGGGAACTTTGGTCCAGCATCGGCTGCTGCTACTCGGATCTTCCAGCGCAACGTGAAGCGGTTCTTCCGGCTTAACGACTCGCAGATGAAGGTCGACGGGATTATCGGCCCAACGACTTGGTTCTGGCTGACACGATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5BsWX) rather than this protein.
PDB ID
5BsWX
Method AlphaFoldv2
Resolution 74.93
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50