Protein

Protein accession
A0A6J5QV70 [UniProt]
Representative
56wtZ
Source
UniProt (cluster: phalp2_24590)
Protein name
Endopeptidase, NLPC/P60 domain containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 73% (predicted by ML model)
Protein sequence
MSTPNLSSQQEYGIRQNFKSLEKQTHIKVPGVDTPMQVDQPTLTPQDIKSMSAGLTGGIKPITGKALGYANDIPIPPTSKIGQAVVRAALQMRGIPYSWGGGGPGGPSKGIAQGANTVGFDCSGLTQYVFAKYGVTIPRVSYEQFRAGTPVPVKAMRPGDLVFFHPGANGPGHVGIFIGNDKFIQAPQTGDVVKISSLSSRSDLMGVRRFG
Physico‐chemical
properties
protein length:211 AA
molecular weight:22258,2 Da
isoelectric point:9,81
hydropathy:-0,22
Representative Protein Details
Accession
56wtZ
Protein name
56wtZ
Sequence length
203 AA
Molecular weight
21394,27370 Da
Isoelectric point
9,87864
Sequence
MQIPRLSIQEDEALRSNLKILQKQTRFKVPNIDVPVEIDLPEVNAPTGAVGDLAAMQNQTGGANIPIPPTSKIGQAVVRAALQMRGIPYSWGGGGPGGPSKGIAQGANTVGFDCSGLVQYAFAKYGVNVPRVTYDQFRAGKPVPTKAMRPGDLVFFRPGANGPGHVGIFIGNGKFLQAPQTGDVVKVSDLSSRSDLVGVRRFG
Other Proteins in cluster: phalp2_24590
Total (incl. this protein): 13 Avg length: 206,8 Avg pI: 9,72
Protein ID Length (AA) pI
56wtZ 203 9,87864
25h4s 218 9,99507
46QQt 203 9,55062
49nFV 203 9,51432
4aGce 228 9,82326
5c7Cv 203 9,87896
5iPpK 236 9,92505
6SIbS 170 9,77207
CcxE 204 9,33272
CjuZ 190 9,16355
RUe8 215 10,16320
Sg1k 204 9,55713
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_2894
wl1m
 22 34,8% 181 8.800E-29
2 phalp2_29089
6VxI8
 38 40,7% 135 2.728E-27
3 phalp2_20916
72mid
 3 44,0% 125 3.308E-26
4 phalp2_40507
4EDHv
 24 42,4% 132 3.308E-26
5 phalp2_16267
7ML59
 15 39,5% 129 8.427E-26
6 phalp2_14587
5e6hT
 9 38,7% 129 4.002E-25
7 phalp2_30781
bmLo
 6 33,5% 182 1.391E-24
8 phalp2_39986
1Nc5e
 7 32,2% 192 1.677E-23
9 phalp2_2843
8JxjE
 191 36,1% 130 4.262E-23
10 phalp2_16997
8aQrJ
 8 39,7% 146 1.853E-19

Domains

Domains [InterPro]
NLPC_P60
Representative sequence (used for alignment): 56wtZ (203 AA)
Member sequence: A0A6J5QV70 (211 AA)
1 203 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00877

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR797105 [NCBI]
CDS location
range 35224 -> 35859
strand +
CDS
ATGAGCACACCAAACCTGTCAAGCCAACAAGAGTATGGCATTCGCCAGAACTTTAAGTCTTTGGAGAAGCAGACGCACATTAAGGTTCCGGGTGTTGACACTCCTATGCAGGTTGATCAGCCTACGTTGACGCCACAAGATATTAAAAGTATGTCGGCTGGTTTGACGGGTGGAATTAAGCCCATTACTGGTAAAGCGCTTGGGTATGCAAACGACATTCCTATACCGCCTACGTCTAAGATTGGGCAGGCCGTTGTAAGGGCTGCGCTTCAGATGCGTGGCATTCCTTACTCGTGGGGCGGCGGCGGTCCGGGTGGTCCGTCTAAAGGTATTGCGCAGGGCGCTAACACGGTGGGCTTTGATTGTTCTGGTTTGACGCAGTACGTGTTTGCTAAGTATGGCGTTACCATTCCGCGTGTGTCGTACGAACAGTTTAGGGCTGGTACGCCAGTCCCAGTTAAGGCCATGCGTCCCGGCGACTTAGTGTTTTTTCATCCGGGGGCTAATGGTCCGGGTCATGTTGGTATTTTTATTGGTAACGACAAGTTTATTCAAGCGCCACAAACCGGAGACGTTGTTAAGATTAGTAGCCTGTCGAGTCGTAGTGATTTGATGGGTGTAAGAAGGTTCGGATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (56wtZ) rather than this protein.
PDB ID
56wtZ
Method AlphaFoldv2
Resolution 77.86
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50