Protein

Protein accession
A0A6J5QHB9 [UniProt]
Representative
Isow
Source
UniProt (cluster: phalp2_11511)
Protein name
CHAP domain containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MSVDDFISTYNGVHIDEDGYYGAQCWDVSARYAREVVGCPSFPTGSGGAEGIYRLFQEPIPQYFVRIANDPKDPDQLPQKGDVAVWQASFSPPYGHTALVISADSSGPTVLEQNGNNPGGVSYIKKRGWTGVSGWLRPKIQGGLIMNEESGAELYRTGLHRDPESPDAARQWNGQTSAQAIRSLRASAEWQGTNSTLVNFPKVVAERDAANGALNQVSIERDQLKSQVLTLIERPTQEVVNTLNNKVDELVKVQNIKDGEISRLNQENESLKAQVGNNTKWETLKALLRELIGKGV
Physico‐chemical
properties
protein length:296 AA
molecular weight:32484,8 Da
isoelectric point:5,28
hydropathy:-0,54
Representative Protein Details
Accession
Isow
Protein name
Isow
Sequence length
230 AA
Molecular weight
25882,69340 Da
Isoelectric point
5,62151
Sequence
MTNAQRAERFAAKYTGQYIDEDKWYGSQCWDVSARYAREEYGCPSFNTGSGGAEGLYRIYAQPIPQFFDKISGSQLQGGDIAVWDKTFYEPWGHTAVVLWREGNTVWVIEQDGSKDPNGDGIADGVAYVVQRTITSKINGLRPKGKAIVMTEDGVRFGILAVTGGKPMKEYEIEVKYWTNRDPAEFAKYLYGMSDNYMVQAYKDIASLKKQLADSGNTEFVETKVYTKKS
Other Proteins in cluster: phalp2_11511
Total (incl. this protein): 3 Avg length: 258,0 Avg pI: 5,36
Protein ID Length (AA) pI
Isow 230 5,62151
4UPKC 248 5,18505
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_39669
6VLbS
 1 29,1% 216 7.811E-14
2 phalp2_7271
3X4sS
 15 28,8% 149 9.747E-12
3 phalp2_15913
4FuWg
 22 27,0% 196 5.897E-11
4 phalp2_18809
1hN6j
 3 29,8% 151 3.547E-10
5 phalp2_39580
6iLgH
 177 27,6% 152 6.960E-09
6 phalp2_1684
7Jr1a
 2 24,6% 227 5.528E-08
7 phalp2_1863
3PtAT
 1 26,4% 174 1.799E-07
8 phalp2_34225
35z4C
 4 26,8% 149 1.886E-06
9 phalp2_9824
8rgSu
 7 24,6% 162 1.090E-05

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): Isow (230 AA)
Member sequence: A0A6J5QHB9 (296 AA)
1 230 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR797026 [NCBI]
CDS location
range 17212 -> 18102
strand -
CDS
ATGTCGGTTGATGATTTTATCTCCACATATAACGGTGTTCATATAGATGAAGACGGATATTATGGGGCACAGTGCTGGGATGTTTCGGCAAGATACGCTCGTGAAGTGGTCGGTTGCCCAAGTTTCCCTACTGGTTCGGGGGGTGCAGAAGGCATATATAGGCTATTTCAAGAACCTATCCCACAATATTTTGTCAGAATCGCAAATGACCCAAAAGACCCTGACCAGCTTCCCCAAAAGGGGGATGTGGCTGTATGGCAGGCTTCTTTTAGCCCACCCTATGGCCACACAGCCCTTGTTATTAGTGCAGACTCTAGTGGGCCTACTGTCCTTGAACAGAATGGCAATAACCCCGGGGGGGTATCATATATAAAGAAGCGTGGCTGGACCGGCGTGTCCGGCTGGCTACGCCCTAAAATACAAGGAGGATTAATAATGAACGAAGAAAGTGGTGCGGAATTATACCGGACTGGTCTCCACCGAGATCCAGAAAGCCCGGATGCAGCTCGACAGTGGAATGGACAGACGTCGGCACAAGCCATACGTAGTCTACGTGCCTCGGCCGAATGGCAGGGCACAAACAGTACACTTGTTAATTTCCCGAAGGTAGTCGCAGAACGTGATGCCGCTAATGGTGCATTGAATCAAGTGTCTATTGAACGAGATCAGCTTAAGAGCCAGGTCCTAACACTAATTGAACGCCCTACACAAGAAGTGGTTAATACTCTAAACAATAAGGTTGATGAACTAGTCAAGGTGCAAAACATAAAGGACGGCGAAATCAGCCGCCTTAACCAAGAAAATGAGTCCCTAAAAGCCCAGGTTGGCAACAACACTAAGTGGGAAACACTCAAAGCGTTACTACGTGAACTAATAGGAAAAGGAGTCTAA
CDS Source ID
[NCBI]
CDS Source
LR797394 [NCBI]
CDS location
range 37759 -> 38649
strand -
CDS
ATGTCGGTTGATGATTTTATCTCCACATATAACGGTGTTCATATAGATGAAGACGGATATTATGGGGCACAGTGCTGGGATGTTTCGGCAAGATACGCTCGTGAAGTGGTCGGTTGCCCAAGTTTCCCTACTGGTTCGGGGGGTGCAGAAGGCATATATAGGCTATTTCAAGAACCTATCCCACAATATTTTGTCAGAATCGCAAATGACCCAAAAGACCCTGACCAGCTTCCCCAAAAGGGGGATGTGGCTGTATGGCAGGCTTCTTTTAGCCCACCCTATGGCCACACAGCCCTTGTTATTAGTGCAGACTCTAGTGGGCCTACTGTCCTTGAACAGAATGGCAATAACCCCGGGGGGGTATCATATATAAAGAAGCGTGGCTGGACCGGCGTGTCCGGCTGGCTACGCCCTAAAATACAAGGAGGATTAATAATGAACGAAGAAAGTGGTGCGGAATTATACCGGACTGGTCTCCACCGAGATCCAGAAAGCCCGGATGCAGCTCGACAGTGGAATGGACAGACGTCGGCACAAGCCATACGTAGTCTACGTGCCTCGGCCGAATGGCAGGGCACAAACAGTACACTTGTTAATTTCCCGAAGGTAGTCGCAGAACGTGATGCCGCTAATGGTGCATTGAATCAAGTGTCTATTGAACGAGATCAGCTTAAGAGCCAGGTCCTAACACTAATTGAACGCCCTACACAAGAAGTGGTTAATACTCTAAACAATAAGGTTGATGAACTAGTCAAGGTGCAAAACATAAAGGACGGCGAAATCAGCCGCCTTAACCAAGAAAATGAGTCCCTAAAAGCCCAGGTTGGCAACAACACTAAGTGGGAAACACTCAAAGCGTTACTACGTGAACTAATAGGAAAAGGAGTCTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (Isow) rather than this protein.
PDB ID
Isow
Method AlphaFoldv2
Resolution 72.91
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50