Protein

Protein accession
A0A6J5Q4S1 [UniProt]
Representative
5kjz4
Source
UniProt (cluster: phalp2_14599)
Protein name
N-acetylmuramoyl-L-alanine amidase domain
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MFAYDLRHWKTIEEFKTHLSQHLPAVARWARGVVIHHTWKPGVNDWRGAPTMEGMKNYYVAMGWTAGPHLFIAGDSPNPETAGIWQMTPLNLRGIHAGRYNTTHWGIEVVGNYDAQPWGAQTNDLTLGAAAALMQWQTIPATYNTVRGHRETGSPKTCPGRMVNMDTFRAELAAMMRGK
Physico‐chemical
properties
protein length:179 AA
molecular weight:20100,7 Da
isoelectric point:9,37
hydropathy:-0,44
Representative Protein Details
Accession
5kjz4
Protein name
5kjz4
Sequence length
243 AA
Molecular weight
26758,12890 Da
Isoelectric point
8,46916
Sequence
MPFTADIRQFTLKTFADYLDALPRPDWPGENNPRGSVYHNTYRPTEAQWAGRASMVSMQRDYTAKGWSAGPHFFLALGSPNPKNDGIWQMTPPTVPGVHGVSCNPTHFGIELVGDFQARAPSLPQQQLLIDVLVLLHRWAGLGPRLIAHRDCITRTCPGQAFYDLKPQLVARLTARLHQAGSYRVRASMWVSETPTTRGPIALDGKAAVYTGDTIEIDEVRADGYAHLANGVGFVPIGGLERL
Other Proteins in cluster: phalp2_14599
Total (incl. this protein): 9 Avg length: 221,8 Avg pI: 8,42
Protein ID Length (AA) pI
5kjz4 243 8,46916
4eki5 235 9,09747
5EHQH 239 8,29755
6KkUc 248 7,14974
6RYJR 247 7,77561
8tAnD 182 8,77126
ZsUH 240 9,04300
A0A6J5NII8 183 7,79244
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_16655
hxf3
 1 53,9% 213 1.992E-65
2 phalp2_21491
8fb4x
 3 36,4% 181 2.896E-45
3 phalp2_9491
TzD8
 9 35,9% 181 1.103E-42
4 phalp2_16512
6XJJ2
 370 33,8% 189 1.686E-35
5 phalp2_6420
fLnR
 15 31,1% 186 3.381E-26
6 phalp2_20375
2VzXO
 6 22,1% 294 1.394E-22
7 phalp2_13177
2nG2h
 13 24,0% 204 1.783E-16
8 phalp2_1217
gjUx
 8 20,2% 242 3.689E-15
9 phalp2_39380
4H4oF
 116 21,5% 167 5.480E-11
10 phalp2_1638
8s39A
 1 25,9% 181 2.423E-10

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 5kjz4 (243 AA)
Member sequence: A0A6J5Q4S1 (179 AA)
1 243 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796972 [NCBI]
CDS location
range 23159 -> 23698
strand -
CDS
ATGTTTGCCTACGATTTGCGCCACTGGAAAACCATAGAAGAATTCAAAACTCACTTATCCCAGCATTTGCCCGCCGTCGCCCGTTGGGCCCGGGGCGTGGTAATCCATCACACATGGAAACCCGGGGTAAACGATTGGCGGGGCGCCCCTACGATGGAGGGGATGAAGAATTATTACGTGGCGATGGGTTGGACGGCCGGCCCTCACCTATTCATTGCGGGCGATTCACCCAACCCCGAAACCGCCGGTATATGGCAAATGACGCCGTTAAATTTACGGGGGATTCACGCCGGGCGTTACAATACAACCCACTGGGGTATTGAGGTGGTAGGCAATTACGACGCTCAACCGTGGGGCGCCCAAACGAATGATTTAACGTTGGGAGCGGCGGCCGCCCTTATGCAGTGGCAAACAATTCCCGCCACATACAACACGGTACGGGGGCACCGTGAAACGGGTTCGCCCAAAACGTGCCCCGGGCGTATGGTAAATATGGACACGTTCCGCGCCGAATTGGCGGCAATGATGAGGGGGAAATAA
CDS Source ID
[NCBI]
CDS Source
LR797077 [NCBI]
CDS location
range 23159 -> 23698
strand -
CDS
ATGTTTGCCTACGATTTGCGCCACTGGAAAACCATAGAAGAATTCAAAACTCACTTATCCCAGCATTTGCCCGCCGTCGCCCGTTGGGCCCGGGGCGTGGTAATCCATCACACATGGAAACCCGGGGTAAACGATTGGCGGGGCGCCCCTACGATGGAGGGGATGAAGAATTATTACGTGGCGATGGGTTGGACGGCCGGCCCTCACCTATTCATTGCGGGCGATTCACCCAACCCCGAAACCGCCGGTATATGGCAAATGACGCCGTTAAATTTACGGGGGATTCACGCCGGGCGTTACAATACAACCCACTGGGGTATTGAGGTGGTAGGCAATTACGACGCTCAACCGTGGGGCGCCCAAACGAATGATTTAACGTTGGGAGCGGCGGCCGCCCTTATGCAGTGGCAAACAATTCCCGCCACATACAACACGGTACGGGGGCACCGTGAAACGGGTTCGCCCAAAACGTGCCCCGGGCGTATGGTAAATATGGACACGTTCCGCGCCGAATTGGCGGCAATGATGAGGGGGAAATAA
CDS Source ID
[NCBI]
CDS Source
LR797136 [NCBI]
CDS location
range 23159 -> 23698
strand -
CDS
ATGTTTGCCTACGATTTGCGCCACTGGAAAACCATAGAAGAATTCAAAACTCACTTATCCCAGCATTTGCCCGCCGTCGCCCGTTGGGCCCGGGGCGTGGTAATCCATCACACATGGAAACCCGGGGTAAACGATTGGCGGGGCGCCCCTACGATGGAGGGGATGAAGAATTATTACGTGGCGATGGGTTGGACGGCCGGCCCTCACCTATTCATTGCGGGCGATTCACCCAACCCCGAAACCGCCGGTATATGGCAAATGACGCCGTTAAATTTACGGGGGATTCACGCCGGGCGTTACAATACAACCCACTGGGGTATTGAGGTGGTAGGCAATTACGACGCTCAACCGTGGGGCGCCCAAACGAATGATTTAACGTTGGGAGCGGCGGCCGCCCTTATGCAGTGGCAAACAATTCCCGCCACATACAACACGGTACGGGGGCACCGTGAAACGGGTTCGCCCAAAACGTGCCCCGGGCGTATGGTAAATATGGACACGTTCCGCGCCGAATTGGCGGCAATGATGAGGGGGAAATAA
CDS Source ID
[NCBI]
CDS Source
LR797444 [NCBI]
CDS location
range 4875 -> 5414
strand +
CDS
ATGTTTGCCTACGATTTGCGCCACTGGAAAACCATAGAAGAATTCAAAACTCACTTATCCCAGCATTTGCCCGCCGTCGCCCGTTGGGCCCGGGGCGTGGTAATCCATCACACATGGAAACCCGGGGTAAACGATTGGCGGGGCGCCCCTACGATGGAGGGGATGAAGAATTATTACGTGGCGATGGGTTGGACGGCCGGCCCTCACCTATTCATTGCGGGCGATTCACCCAACCCCGAAACCGCCGGTATATGGCAAATGACGCCGTTAAATTTACGGGGGATTCACGCCGGGCGTTACAATACAACCCACTGGGGTATTGAGGTGGTAGGCAATTACGACGCTCAACCGTGGGGCGCCCAAACGAATGATTTAACGTTGGGAGCGGCGGCCGCCCTTATGCAGTGGCAAACAATTCCCGCCACATACAACACGGTACGGGGGCACCGTGAAACGGGTTCGCCCAAAACGTGCCCCGGGCGTATGGTAAATATGGACACGTTCCGCGCCGAATTGGCGGCAATGATGAGGGGGAAATAA
CDS Source ID
[NCBI]
CDS Source
LR797495 [NCBI]
CDS location
range 23159 -> 23698
strand -
CDS
ATGTTTGCCTACGATTTGCGCCACTGGAAAACCATAGAAGAATTCAAAACTCACTTATCCCAGCATTTGCCCGCCGTCGCCCGTTGGGCCCGGGGCGTGGTAATCCATCACACATGGAAACCCGGGGTAAACGATTGGCGGGGCGCCCCTACGATGGAGGGGATGAAGAATTATTACGTGGCGATGGGTTGGACGGCCGGCCCTCACCTATTCATTGCGGGCGATTCACCCAACCCCGAAACCGCCGGTATATGGCAAATGACGCCGTTAAATTTACGGGGGATTCACGCCGGGCGTTACAATACAACCCACTGGGGTATTGAGGTGGTAGGCAATTACGACGCTCAACCGTGGGGCGCCCAAACGAATGATTTAACGTTGGGAGCGGCGGCCGCCCTTATGCAGTGGCAAACAATTCCCGCCACATACAACACGGTACGGGGGCACCGTGAAACGGGTTCGCCCAAAACGTGCCCCGGGCGTATGGTAAATATGGACACGTTCCGCGCCGAATTGGCGGCAATGATGAGGGGGAAATAA
CDS Source ID
[NCBI]
CDS Source
LR798420 [NCBI]
CDS location
range 23159 -> 23698
strand -
CDS
ATGTTTGCCTACGATTTGCGCCACTGGAAAACCATAGAAGAATTCAAAACTCACTTATCCCAGCATTTGCCCGCCGTCGCCCGTTGGGCCCGGGGCGTGGTAATCCATCACACATGGAAACCCGGGGTAAACGATTGGCGGGGCGCCCCTACGATGGAGGGGATGAAGAATTATTACGTGGCGATGGGTTGGACGGCCGGCCCTCACCTATTCATTGCGGGCGATTCACCCAACCCCGAAACCGCCGGTATATGGCAAATGACGCCGTTAAATTTACGGGGGATTCACGCCGGGCGTTACAATACAACCCACTGGGGTATTGAGGTGGTAGGCAATTACGACGCTCAACCGTGGGGCGCCCAAACGAATGATTTAACGTTGGGAGCGGCGGCCGCCCTTATGCAGTGGCAAACAATTCCCGCCACATACAACACGGTACGGGGGCACCGTGAAACGGGTTCGCCCAAAACGTGCCCCGGGCGTATGGTAAATATGGACACGTTCCGCGCCGAATTGGCGGCAATGATGAGGGGGAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5kjz4) rather than this protein.
PDB ID
5kjz4
Method AlphaFoldv2
Resolution 94.51
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50