Protein

Protein accession
A0A6J5PW15 [UniProt]
Representative
4HE7L
Source
UniProt (cluster: phalp2_14461)
Protein name
CHAP domain containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MDYDGFIARWLGKAIDWDGYYGPQCVDLVAQYCADNGKPVAYANAKDWANNPALSGAFNWTDNNPADPNQYPNRGDIVVFNGNLPGSGGYGHI
Physico‐chemical
properties
protein length:93 AA
molecular weight:10130,9 Da
isoelectric point:4,25
hydropathy:-0,53
Representative Protein Details
Accession
4HE7L
Protein name
4HE7L
Sequence length
234 AA
Molecular weight
25646,01790 Da
Isoelectric point
4,36145
Sequence
MDYDGFINRWLGKAIDWDGMYGAQCVDEIAQYCSDNNKPVAYANAKDWWQHPSLIGAFDFIANDPNDPNQLPNRGDVVIFNGNQPGSGGYGHINIFDMQQDTDHWQGLDQNWGGQYVHFVTGHVWTYVIGWMRPKAAPAPIPAPDPAPDPGVPPAPIPDPTTTVAPETTTTTTTQAPTTTATTTDTTTAQPVETTTATTTWTTTAPPPQVGGQATWFEIVWSTIIRFIERLQGK
Other Proteins in cluster: phalp2_14461
Total (incl. this protein): 9 Avg length: 182,6 Avg pI: 5,20
Protein ID Length (AA) pI
4HE7L 234 4,36145
1ZbrH 220 7,76406
3fGBQ 226 4,81485
hCyy 237 4,41260
hxuj 215 4,37941
A0A6J5QJW8 110 4,21969
A0A6J5RX90 213 8,37272
A0A6J5S9E5 95 4,25255
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_8656
45aVs
 41 35,2% 187 7.765E-25
2 phalp2_9707
2agA0
 2 36,0% 172 1.086E-22
3 phalp2_11577
18WTO
 29 35,8% 156 7.544E-15
4 phalp2_10799
3WA57
 47 31,8% 157 1.555E-13
5 phalp2_796
28Kwv
 80 27,7% 155 4.091E-09
6 phalp2_26341
1gBcI
 110 31,4% 156 4.583E-07
7 phalp2_23555
7sVyK
 88 28,9% 152 8.786E-04

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 4HE7L (234 AA)
Member sequence: A0A6J5PW15 (93 AA)
1 234 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796938 [NCBI]
CDS location
range 1 -> 279
strand -
CDS
ATGGACTACGATGGTTTTATAGCAAGATGGCTCGGTAAAGCAATTGACTGGGACGGATACTATGGACCTCAGTGCGTAGATTTGGTGGCCCAGTATTGTGCAGATAATGGCAAACCTGTAGCTTATGCAAATGCTAAGGATTGGGCAAATAACCCAGCTTTGTCGGGTGCTTTTAATTGGACCGATAATAACCCTGCTGATCCTAATCAGTATCCTAACAGAGGTGATATAGTCGTATTCAATGGTAATCTACCTGGCTCTGGTGGTTACGGACACATC

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4HE7L) rather than this protein.
PDB ID
4HE7L
Method AlphaFoldv2
Resolution 74.82
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50