Protein

Protein accession
A0A6J5PGU7 [UniProt]
Representative
4pbkX
Source
UniProt (cluster: phalp2_34915)
Protein name
Peptidase M23
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKPIKLGVITFPYMAKYRNGTRHKGVDYRASIGTPVQACVGGVVVHAGRHIYKKGWGLSFGIHCIVDNDRFPDGTAGLWAGYCHLQAVGVHVGQRVAKGDLVGISGNTGNSTGPHLHLQILSQRTWNPTKIKNPQKWIDA
Physico‐chemical
properties
protein length:140 AA
molecular weight:15238,4 Da
isoelectric point:9,97
hydropathy:-0,23
Representative Protein Details
Accession
4pbkX
Protein name
4pbkX
Sequence length
141 AA
Molecular weight
15432,44970 Da
Isoelectric point
10,32482
Sequence
MAYPLKAWRTTFPYGVKYSNGGIHKGIDGAAKVGTPVYAAVSGRVVHSGVHKFRKGWGSAFGIHVIVDNDKFKDGDAGLWAGYCHLSKVALAVGQRVERGDLIGWSGNTGRSTGPHLHFQILASRTWNPRKHVNPQRWLKA
Other Proteins in cluster: phalp2_34915
Total (incl. this protein): 159 Avg length: 143,0 Avg pI: 10,02
Protein ID Length (AA) pI
4pbkX 141 10,32482
131OI 149 9,18612
1931i 141 10,17661
19ORZ 140 10,09821
19OyC 140 9,96831
1JRGF 143 9,54282
1JRRE 140 10,29007
1JXDi 140 10,00403
1JZBf 140 10,17152
1K2uM 141 10,05393
1K9sG 143 10,10602
1KaWn 139 10,05831
1Kef6 140 10,00454
1KgVd 141 10,21374
1Kil8 140 10,03845
1KkEi 152 9,96090
1Kmhs 140 10,10885
1Llja 140 10,11021
1dZzY 140 9,96019
1h61p 167 9,49911
1vFwN 140 10,21729
1yDOx 139 9,87025
27Pm2 140 10,11021
2R8NC 140 10,41230
2kTs4 139 10,50727
30C9t 152 9,20675
30UcW 158 9,43355
30oVw 161 9,44799
316if 152 9,20675
35aD7 150 9,91867
38bgI 141 10,25539
38hZX 139 10,15166
38i1G 140 10,15450
38k79 140 10,17152
38ll7 141 10,05276
3R5O 144 10,38903
3W101 140 10,08751
3WiiE 140 10,21729
45Qzd 140 10,19169
46FV9 161 9,56674
46MoY 149 9,39448
48YL5 153 9,30177
49cFd 139 10,10750
49h2J 152 9,86374
49hCW 140 9,88508
4Ge89 140 10,04174
4IR4m 146 10,21200
4Jeak 160 9,38461
4KT7X 140 10,19601
4a6Lq 140 10,21916
4aEQD 166 9,54076
4aOjN 140 10,04935
4ahZf 158 9,32640
4bEuN 161 9,54327
4bOGs 161 9,33929
4bp7g 140 10,25352
4e4Up 158 9,39519
4hgYW 152 9,90655
4llxL 140 10,05960
4m3hC 140 10,21729
4nNrg 140 10,03845
4qobD 140 10,32482
503a3 152 10,15404
50oth 141 10,26706
51AXl 140 10,03845
51xRz 140 10,25352
53gyV 140 10,13722
54BaV 140 10,22979
54COl 140 10,10885
54VMe 140 10,22979
55CWD 140 10,08751
55hW8 140 10,15024
55tFT 141 10,26854
56NQH 141 10,15308
56wWY 140 10,19318
57KWy 140 10,10885
57S5A 140 10,20678
580L1 140 10,13715
589Hu 140 10,19169
589W2 140 10,07094
591nF 140 10,17152
5AMCr 140 10,25352
5CW88 140 10,05276
5DITT 140 10,17319
5ayod 140 10,12432
5azD7 148 9,75073
5bLeg 140 10,19169
5c5Qf 126 10,19969
5eMfw 140 10,17390
5eOZO 140 10,25906
5ePmt 104 9,67330
5eroe 133 10,16172
5f4uU 140 10,05960
5fA2u 139 10,61409
5fRX9 140 10,15308
5fX8h 139 10,06089
5fn4y 140 10,22825
5g9JF 140 10,11021
5gH94 140 10,10730
5ghAd 140 10,05276
5guVF 140 10,21729
5gwdM 139 10,10750
5h8PA 141 10,22825
5helc 148 10,00951
5iv2j 148 9,91790
5jlwR 140 10,21729
5kNYb 139 10,04838
5kODI 140 10,37298
5krGz 149 9,32214
5lXsz 140 10,29007
5mhEf 169 10,38929
5mr5c 140 10,15598
5nuvt 140 10,17390
5tAwu 139 10,05960
5tkuH 141 10,03845
5u9Tl 141 9,95387
5u9vE 140 10,09589
5uAbK 141 10,36331
5wmg 144 10,54498
6ACST 140 10,22825
6Gn2m 141 9,97018
6IFZb 140 10,15308
6Mpuo 145 9,60729
6QsqT 161 9,44805
6fMbr 105 9,94394
6xLsT 140 10,00345
6xMga 140 10,17319
6xwnL 140 10,29007
6xyev 140 10,29136
6yqnr 141 10,25539
7IB2d 139 10,21555
7WWAd 140 10,09589
7Xb9w 159 9,35502
81L1I 150 10,77049
81Mxy 159 10,50088
81sJ6 143 9,54282
83Ey8 150 9,54243
88g8k 140 10,00454
8F3Gc 146 10,45073
8nT9N 143 9,34432
8otbJ 143 9,69716
C8Yd 140 10,05393
FFfy 145 10,13612
FjGB 139 9,95935
JpGG 140 10,05386
Jvc7 140 10,21729
KSbm 140 10,17390
LNbW 140 10,05276
LlER 141 9,95361
Lnfr 143 9,96560
RQ1y 155 9,46739
SZaO 155 9,42381
SjrB 161 9,44799
crhU 127 9,77349
jRUk 140 10,17390
sFZJ 140 10,29007
A0A6J5MJ89 140 10,12916
A0A6J5RC45 148 10,22606
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_32582
1JRhw
 2 62,7% 86 4.175E-43
2 phalp2_40658
5cY9d
 663 42,6% 143 1.476E-42
3 phalp2_32775
2hNmx
 15 39,4% 147 2.044E-32
4 phalp2_21998
4ZChj
 22 38,0% 142 3.493E-31
5 phalp2_25136
1CoHT
 3 38,8% 139 4.789E-31
6 phalp2_33390
6Q97d
 9 35,9% 142 2.888E-29
7 phalp2_28422
1FQvo
 13 42,1% 114 4.930E-28
8 phalp2_14848
7w0BH
 74 36,1% 144 1.269E-27
9 phalp2_26412
1I66q
 14 42,1% 102 1.740E-27
10 phalp2_18623
3ebV
 83 42,1% 140 2.384E-27

Domains

Domains [InterPro]
PET_M23
Representative sequence (used for alignment): 4pbkX (141 AA)
Member sequence: A0A6J5PGU7 (140 AA)
1 141 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796824 [NCBI]
CDS location
range 12334 -> 12756
strand +
CDS
ATGAAGCCGATTAAACTTGGAGTAATCACATTTCCATACATGGCCAAGTATCGAAACGGTACACGCCATAAGGGAGTAGATTACCGAGCCAGCATTGGAACACCTGTCCAAGCCTGTGTAGGCGGGGTAGTAGTCCATGCAGGGCGACACATCTACAAAAAGGGTTGGGGCCTGAGTTTCGGAATTCACTGTATTGTCGATAACGATAGGTTTCCAGACGGCACAGCGGGACTGTGGGCGGGTTACTGCCACTTACAGGCTGTAGGTGTCCATGTGGGCCAGCGTGTCGCCAAGGGCGATTTGGTGGGCATTTCAGGCAACACAGGCAACTCGACTGGGCCTCATCTACACTTGCAGATCTTGTCCCAGCGCACATGGAACCCAACCAAGATCAAAAACCCACAGAAATGGATTGATGCATGA
CDS Source ID
[NCBI]
CDS Source
LR796992 [NCBI]
CDS location
range 2282 -> 2704
strand -
CDS
ATGAAGCCGATTAAACTTGGAGTAATCACATTTCCATACATGGCCAAGTATCGAAACGGTACACGCCATAAGGGAGTAGATTACCGAGCCAGCATTGGAACACCTGTCCAAGCCTGTGTAGGCGGGGTAGTAGTCCATGCAGGGCGACACATCTACAAAAAGGGTTGGGGCCTGAGTTTCGGAATTCACTGTATTGTCGATAACGATAGGTTTCCAGACGGCACAGCGGGACTGTGGGCGGGTTACTGCCACTTACAGGCTGTAGGTGTCCATGTGGGCCAGCGTGTCGCCAAGGGCGATTTGGTGGGCATTTCAGGCAACACAGGCAACTCGACTGGGCCTCATCTACACTTGCAGATCTTGTCCCAGCGCACATGGAACCCAACCAAGATCAAAAACCCACAGAAATGGATTGATGCATGA
CDS Source ID
[NCBI]
CDS Source
LR797521 [NCBI]
CDS location
range 7001 -> 7423
strand +
CDS
ATGAAGCCGATTAAACTTGGAGTAATCACATTTCCATACATGGCCAAGTATCGAAACGGTACACGCCATAAGGGAGTAGATTACCGAGCCAGCATTGGAACACCTGTCCAAGCCTGTGTAGGCGGGGTAGTAGTCCATGCAGGGCGACACATCTACAAAAAGGGTTGGGGCCTGAGTTTCGGAATTCACTGTATTGTCGATAACGATAGGTTTCCAGACGGCACAGCGGGACTGTGGGCGGGTTACTGCCACTTACAGGCTGTAGGTGTCCATGTGGGCCAGCGTGTCGCCAAGGGCGATTTGGTGGGCATTTCAGGCAACACAGGCAACTCGACTGGGCCTCATCTACACTTGCAGATCTTGTCCCAGCGCACATGGAACCCAACCAAGATCAAAAACCCACAGAAATGGATTGATGCATGA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4pbkX) rather than this protein.
PDB ID
4pbkX
Method AlphaFoldv2
Resolution 91.90
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50