Protein

Protein accession
A0A6J5N490 [UniProt]
Representative
36BX3
Source
UniProt (cluster: phalp2_1799)
Protein name
N-acetylmuramoyl-L-alanine amidase domain containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MDIEFIPANRNNYFTAQEAQGYYGLPRTVDTIVIHHWGDPNDRPTFASNLNYLLDAPNGYPSANCVIGLDESTNTVRIVDTVRYPDVAFTSGGSINAKSVAIECDPLAETSNGFANDIYKAIGYRVWQWRTQLGWRVPLSRHSDYFSTACPGAMDLGRIDAEADKWANGGYNPKPTPTPTIKFTKLPVPKIYVCKLSPTTLWRFNVSKWSEFEPQSVFSLGSKITVFGYADHPLGARYLMTQFSFGNADATGTPDHYWGFNEKDMVEYVEPTPEPVPPTPEPTPPDPTPEPPVPTPTPEYPNWFVSFWIELWESIKNILHIK
Physico‐chemical
properties
protein length:322 AA
molecular weight:36205,2 Da
isoelectric point:5,01
hydropathy:-0,43
Representative Protein Details
Accession
36BX3
Protein name
36BX3
Sequence length
359 AA
Molecular weight
39364,95530 Da
Isoelectric point
5,82977
Sequence
MSQVETIIADRDAYFTPSEGAAYYGRARSLDEIVIHHWDSKEKRLAGQVSFNGVLQHLLHAGVPSANDIIGFDEGAGRVRVVNSVQYPNVAFTSGSTYTARGKYINQVSVGFECDPLGEVSGHAQQGAVLEAIAQRALDYCKLVDRLLPLSMHRDYAQTACPGEMPLDWLRSRLAQLWQEYKNPAPAPSPLPATSTYKRLEKRTWLCNAEPTKLWDLGFTTWPTAKSTAQFSKGHPVEIVGIAYHPLGGEYLMTNYSFGNADTTGVPAHNTGFNKKDMVQAPEPQPIPPAPTPTPTPVPTPVPLPDPTPTPTPVPDPEQPTEHDKEQDKEISALKGTLNSLIALLREFAQNILSKFGKE
Other Proteins in cluster: phalp2_1799
Total (incl. this protein): 4 Avg length: 349,5 Avg pI: 6,25
Protein ID Length (AA) pI
36BX3 359 5,82977
7YPHb 358 8,23779
7ZTry 359 5,91730
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_10949
4Jkr6
 29 29,1% 302 1.229E-35
2 phalp2_9864
2cTO7
 3 31,2% 285 5.267E-28
3 phalp2_16214
4K5QO
 38 27,8% 323 3.539E-16
4 phalp2_36626
25FVY
 29 26,2% 293 4.838E-14
5 phalp2_31553
4f5QX
 101 23,0% 282 1.128E-11
6 phalp2_25234
40uRC
 5 26,4% 227 5.907E-09

Domains

Domains [InterPro]
Unannotated
Unannotated
Unannotated
Representative sequence (used for alignment): 36BX3 (359 AA)
Member sequence: A0A6J5N490 (322 AA)
1 359 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796562 [NCBI]
CDS location
range 32308 -> 33276
strand +
CDS
ATGGACATAGAATTTATACCAGCTAATAGGAACAACTACTTTACAGCACAAGAGGCTCAAGGCTACTATGGTCTACCTCGTACTGTTGATACTATTGTCATTCACCACTGGGGAGATCCGAACGACAGGCCTACATTCGCCAGTAATCTTAATTATCTACTAGATGCACCGAACGGCTATCCTAGTGCTAACTGTGTCATCGGCCTTGATGAGAGTACAAACACTGTAAGGATCGTTGATACTGTCCGTTATCCGGACGTTGCATTCACTTCAGGTGGTTCTATAAATGCCAAGTCAGTAGCGATCGAGTGCGATCCTCTAGCCGAGACTTCAAACGGATTTGCTAATGATATTTATAAAGCGATTGGGTATCGGGTGTGGCAATGGAGGACACAGCTAGGATGGCGAGTTCCATTATCTAGGCACAGCGATTACTTTTCCACAGCTTGCCCAGGGGCTATGGACTTAGGGCGTATTGATGCCGAGGCTGACAAGTGGGCTAACGGTGGCTATAATCCTAAACCTACTCCAACACCGACTATAAAGTTCACTAAACTTCCAGTACCAAAAATATATGTTTGCAAGCTATCACCTACTACACTCTGGAGATTCAATGTATCGAAGTGGTCTGAGTTCGAGCCACAGTCTGTCTTCTCTCTAGGCTCTAAGATAACGGTCTTCGGCTACGCAGATCACCCGTTAGGAGCTCGATACCTTATGACGCAGTTTAGTTTCGGAAATGCTGACGCAACCGGAACACCGGATCATTACTGGGGTTTCAACGAAAAAGATATGGTGGAATATGTCGAACCGACACCAGAACCAGTACCTCCGACTCCAGAGCCTACCCCTCCAGATCCCACACCCGAGCCACCAGTACCGACTCCGACTCCAGAATATCCGAACTGGTTTGTGAGTTTTTGGATTGAACTTTGGGAATCTATAAAGAACATATTGCATATAAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (36BX3) rather than this protein.
PDB ID
36BX3
Method AlphaFoldv2
Resolution 87.59
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50