Protein

Protein accession
A0A6J5MED5 [UniProt]
Representative
2iIba
Source
UniProt (cluster: phalp2_30013)
Protein name
AmiC N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MDKKEFCIFLDAGHGGINPKVKLPNGYTTFPSKCSQHNNGKFHSYGWFFEGVFNRAVTNLIEQYLNDWGMTTMKVYDEIIDTPLSKRVQKANFAAKNYSRSLYLSIHGNAAENKSARGWEAFTSRGQTQSDIYAEYLYKEVKKSYPNWVFRSDLSDGDHDKEERFYVLSKTLMPSVLSENGFFTNFQDAKMMFDPSFQNTIAKCHAKAVIDYAESMGVIMF
Physico‐chemical
properties
protein length:221 AA
molecular weight:25391,4 Da
isoelectric point:7,69
hydropathy:-0,51
Representative Protein Details
Accession
2iIba
Protein name
2iIba
Sequence length
146 AA
Molecular weight
16457,48370 Da
Isoelectric point
8,64626
Sequence
MKPSEFLICLDAGHGGMRNGTGPERYVTYPSKCYQHKVGKFHSYGWFFEGVFNRSLANYLHQYLEDYGFTVKKIYEPVNDTPLNKRCQLAISYSSIAKHSILVSIHGNAATPTARGWEIFTSPTQTKSDLLATCIGEQVKTATPEW
Other Proteins in cluster: phalp2_30013
Total (incl. this protein): 9 Avg length: 172,0 Avg pI: 7,53
Protein ID Length (AA) pI
2iIba 146 8,64626
1LeTc 219 6,05122
345dO 219 6,05207
44JbA 162 6,13448
44iUD 103 9,01186
4qqcF 136 9,18547
5bpzG 219 6,23162
GM8S 123 8,79228
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37494
3aZmq
 1971 43,3% 143 2.026E-33
2 phalp2_28600
7ZUUM
 47 37,8% 140 9.572E-20
3 phalp2_28969
5Zx99
 42 34,1% 129 1.014E-11
4 phalp2_25147
1GsF1
 21 32,1% 112 1.014E-11
5 phalp2_10557
8qr1Y
 1 29,4% 139 5.806E-10
6 phalp2_33525
85Tz
 32 31,4% 140 1.763E-08
7 phalp2_15545
8uE6l
 7 33,3% 111 3.882E-07
8 phalp2_9859
2aUUC
 2 26,2% 137 1.146E-05
9 phalp2_18497
6MPko
 7 25,3% 142 7.198E-05
10 phalp2_26297
13Hnr
 75 26,3% 129 9.770E-05

Domains

Domains [InterPro]
Ami3
Representative sequence (used for alignment): 2iIba (146 AA)
Member sequence: A0A6J5MED5 (221 AA)
1 146 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796437 [NCBI]
CDS location
range 34279 -> 34944
strand +
CDS
ATGGACAAAAAAGAATTTTGTATATTTTTGGATGCTGGTCATGGTGGTATTAATCCTAAAGTAAAATTACCTAATGGATATACTACTTTCCCATCAAAATGTAGCCAACACAATAACGGCAAATTTCATTCCTATGGATGGTTCTTTGAAGGCGTTTTTAACAGAGCCGTTACCAATCTCATTGAACAATATTTGAATGATTGGGGAATGACCACAATGAAAGTTTATGACGAAATAATTGACACGCCTCTAAGCAAAAGAGTACAGAAGGCAAACTTCGCAGCTAAAAATTATAGTCGTTCTTTATATTTAAGCATTCACGGTAACGCAGCTGAAAATAAAAGTGCTAGGGGCTGGGAGGCATTCACATCACGCGGTCAAACACAGTCGGATATTTATGCAGAGTATTTATATAAAGAAGTTAAAAAATCCTATCCAAATTGGGTTTTTCGTTCTGATTTAAGCGACGGGGATCACGACAAAGAAGAAAGGTTTTACGTTTTAAGCAAAACTTTAATGCCTTCGGTGTTATCTGAAAACGGTTTCTTTACTAATTTTCAAGATGCTAAAATGATGTTTGACCCATCATTCCAAAACACAATAGCAAAGTGCCATGCTAAAGCAGTTATTGATTATGCTGAATCAATGGGAGTAATAATGTTTTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2iIba) rather than this protein.
PDB ID
2iIba
Method AlphaFoldv2
Resolution 96.06
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50