Protein

Protein accession
A0A5Q2WA62 [UniProt]
Representative
7cpfr
Source
UniProt (cluster: phalp2_32223)
Protein name
Cell wall hydrolase autolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAAFISAGHHLKDPGAISGQYVERDEMIKFRDSVVAICRGFGLKVITDKDSETLPQYLERIQSGSGSVVVEFHLNASGTGNASGTLAVVGNDADKLDKLFAERLAEATSEVLGIKNRGVMSEADSHRGRLGLMRETGIVALLEVCFIDNKEDMDSFKKNSSVLALRIAEVIKKFDNLLA
Physico‐chemical
properties
protein length:179 AA
molecular weight:19386,9 Da
isoelectric point:5,60
hydropathy:-0,06
Representative Protein Details
Accession
7cpfr
Protein name
7cpfr
Sequence length
249 AA
Molecular weight
26807,27630 Da
Isoelectric point
8,86558
Sequence
MALLLIDDSYISAGHHNSDPGAMANGLRESVMMMEYRDMVSNELFALGATVVNDRDTETLGQYLARINPKGKDVLCEFHADAAGPTATGATGVIADAHTAQDKAFATEMVKATSDVLGIRNRGVIKESQSARGRLAFVRKGGINSLQELFFITNPSDVVAYERGKSALAKEHARIINKYDGGNSTTGNVSTMRTTARLNLRAGAGIGHRVIRTLPLGIEVNVLSISVGWIEVLVCRDKVRGWVSASYLK
Other Proteins in cluster: phalp2_32223
Total (incl. this protein): 3 Avg length: 225,7 Avg pI: 7,42
Protein ID Length (AA) pI
7cpfr 249 8,86558
1f1u7 249 7,79560
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_3696
51zXL
 234 51,7% 172 1.677E-61
2 phalp2_14862
15a1
 46 41,3% 174 6.021E-44
3 phalp2_37678
3Xhrk
 501 44,8% 176 1.693E-31
4 phalp2_29815
2324Y
 17 33,6% 184 3.489E-25
5 phalp2_29178
7BEyZ
 91 36,1% 177 3.514E-21
6 phalp2_23090
4q8sF
 5 34,8% 175 3.440E-19
7 phalp2_18820
1lbSb
 1 32,2% 161 9.792E-18
8 phalp2_34447
4ANo2
 39 29,3% 184 3.299E-17
9 phalp2_24413
4m1OU
 1246 30,5% 177 2.083E-13
10 phalp2_36719
6eCmw
 993 24,6% 247 3.077E-12

Domains

Domains [InterPro]
Ami3
SH3_3
Representative sequence (used for alignment): 7cpfr (249 AA)
Member sequence: A0A5Q2WA62 (179 AA)
1 249 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF08239

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctrTa16
[NCBI] 		2656715 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN582082 [NCBI]
CDS location
range 53379 -> 53918
strand -
CDS
ATGGCTGCATTTATTTCAGCAGGACATCACCTGAAAGACCCCGGCGCAATAAGCGGACAATACGTTGAACGTGATGAAATGATTAAGTTCAGGGATAGTGTCGTTGCTATATGCCGGGGATTTGGATTGAAGGTTATAACGGATAAAGATAGCGAGACGCTGCCTCAGTACCTTGAGAGGATTCAATCAGGCTCAGGCTCTGTGGTGGTTGAGTTTCATCTCAATGCAAGCGGCACAGGTAATGCGTCCGGTACGCTCGCCGTTGTTGGCAATGATGCGGATAAGCTTGACAAGCTATTTGCTGAAAGACTTGCTGAGGCTACATCTGAGGTATTGGGTATAAAGAATAGGGGTGTTATGTCTGAAGCTGACAGCCATCGTGGAAGACTTGGATTGATGAGGGAGACCGGGATAGTGGCGTTGCTTGAGGTGTGCTTTATAGATAACAAGGAAGACATGGATAGCTTTAAAAAGAACAGCTCTGTGCTTGCGCTCAGGATTGCGGAGGTGATAAAGAAGTTCGACAATCTGCTTGCGTGA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7cpfr) rather than this protein.
PDB ID
7cpfr
Method AlphaFoldv2
Resolution 90.47
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50