Protein

Protein accession
A0A5Q2W6C4 [UniProt]
Representative
4m1un
Source
UniProt (cluster: phalp2_39314)
Protein name
PGRP protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MERGTRRRLGIVTKDNMLPRTHILFHHSAIAGLEPQYDRVRDYHNRGGLDKNGKKKWPAGYGCQYAFFLEKNGEIIEANPPERVTWHSGSWLWNARSIAIALAGSLLTEQVTTEQLRALVALTNALQARFSIPDGNLLDHRDVRNTSCPGARIKEMVLREKANHFSSKIDHLRKVIDRTEPPRKTRLQRALARFLALVPL
Physico‐chemical
properties
protein length:200 AA
molecular weight:22835,0 Da
isoelectric point:10,26
hydropathy:-0,52
Representative Protein Details
Accession
4m1un
Protein name
4m1un
Sequence length
208 AA
Molecular weight
23508,77070 Da
Isoelectric point
8,98207
Sequence
MSRQSLSYIVIHHTAAEEKDAAQIKNYHITHGWADVAYDFIIEKDGKVVEGRPLTMKGGHAGVDYYNQNSIGVSVIGNLSKREIYLAQWNSLISLLNKLCENYNIPVDNILFHRDIKATACPGSTMDRDRVRKAVKCTLNKVNIVVDGKIYEPVEKITQRDGKVFVSIYDALNMIGASMNTPVHIRVLQDYFGKKVEYYAVTRTIKIS
Other Proteins in cluster: phalp2_39314
Total (incl. this protein): 3 Avg length: 216,3 Avg pI: 9,57
Protein ID Length (AA) pI
4m1un 208 8,98207
4uLEP 241 9,46410
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12934
2XGYf
 62 33,3% 177 5.606E-29
2 phalp2_19793
4W5p2
 179 37,4% 131 1.733E-27
3 phalp2_13177
2nG2h
 13 31,6% 139 1.057E-23
4 phalp2_5712
4IjX3
 263 33,5% 146 4.386E-22
5 phalp2_28594
878Gz
 18 36,2% 138 1.516E-21
6 phalp2_9720
40UHt
 92 30,8% 136 3.842E-21
7 phalp2_2237
4n15b
 512 34,2% 149 5.237E-21
8 phalp2_7337
4jq41
 32 33,8% 142 5.237E-21
9 phalp2_22314
agEM
 1 31,4% 143 5.237E-21
10 phalp2_464
fli8
 7 31,3% 137 2.923E-19

Domains

Domains [InterPro]
Ami2
Disordered region
Representative sequence (used for alignment): 4m1un (208 AA)
Member sequence: A0A5Q2W6C4 (200 AA)
1 208 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctpQM7
[NCBI] 		2656722 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN582066 [NCBI]
CDS location
range 2640 -> 3242
strand +
CDS
ATGGAGCGAGGAACCAGGAGGCGATTAGGAATTGTAACGAAGGATAATATGCTCCCCCGTACGCACATTCTGTTCCATCACTCAGCCATAGCGGGTCTGGAACCGCAATATGACCGCGTGCGGGATTACCACAATAGGGGCGGCCTCGATAAGAACGGGAAAAAGAAGTGGCCAGCAGGATATGGCTGCCAATACGCTTTTTTTCTGGAAAAGAACGGGGAAATCATCGAAGCAAACCCGCCGGAGAGAGTGACATGGCATTCCGGGAGCTGGCTCTGGAATGCTCGCAGCATTGCTATCGCGCTTGCGGGTAGCCTCCTCACAGAGCAGGTCACCACCGAACAATTACGTGCCCTTGTAGCCCTCACAAATGCCCTACAAGCTCGGTTCTCCATCCCCGACGGGAATTTGCTCGACCATAGGGACGTGCGTAATACGAGCTGTCCTGGAGCACGTATAAAAGAAATGGTATTGCGCGAGAAAGCGAACCATTTTTCAAGTAAAATCGACCATCTCCGCAAGGTGATCGACAGAACAGAGCCCCCGCGCAAGACGCGACTCCAGCGCGCTCTTGCTCGATTTCTCGCACTTGTTCCGCTATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4m1un) rather than this protein.
PDB ID
4m1un
Method AlphaFoldv2
Resolution 81.30
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50