Protein

Protein accession
A0A3G8F8G9 [UniProt]
Representative
2teHi
Source
UniProt (cluster: phalp2_39119)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAKVCLDAGHGGYDPGAVGPSGLKEKDVTLDVVLRVGKYLQQAGIEVVYTRTSDQVLWSASKDLQARCDIANRSGADLFISVHCNSFSNPQAAGTETYSLSTTGNGRKVAEFIQAELISALNLTNRGLKTANYYVLKRTSMPATLTEVAFISNPREEALLRDPAFRDRAALAITKGIAKYFGIDILPAPVPRPGPAPNAVKIRVGNLVLDGLIIGNISYAPVRALAEALGRQVVWNEAEKAVDVR
Physico‐chemical
properties
protein length:245 AA
molecular weight:26265,8 Da
isoelectric point:8,94
hydropathy:-0,03
Representative Protein Details
Accession
2teHi
Protein name
2teHi
Sequence length
512 AA
Molecular weight
56725,79230 Da
Isoelectric point
6,28062
Sequence
MIQSKGTINFGHGEKSDGTFDPGSVGQTGLKESDVVKAVGIIVVSELKRLGHDINFIQSGDLWAVVDSSNDFDSEWFVSIHNNSYTDKSAHGIETHISALGSNAEKLARAIQSNLINDIKLTDRGIKVSGLYVNKYTNCPSCLVELPFISNSTEEALLANPDFQRKCAISIVKGIQQYLGLEYVKEQSNQKTPILGAESITVEQCNQFIRKVNPNAINIAQYYKKYGELLGIKWGYAFSQMVKETNYLRFGGDVVLAKNNYCGLGTIGGGVKGVYFDSPELGVLAHMEHLYAYCCKDSLPSNLPKIDPRFDLVARGIATTWEDLNGRWAVPGIGYGEDICKIYNQICKETATVVQPVPIIVTPVVPPSIPLPSLIFTYPNNAKIINDDLYIRDINGVQIPNRYVSKGDDVTVIEILYEKQLVLLEYPTSSGVKSGYVKNIVNCFSYYYQGVFKNGSTPESTYNDNNIAFGKLDPYETATPLYRKNGFLKIMYNTPKGQKTGFTHWSGGFDKF
Other Proteins in cluster: phalp2_39119
Total (incl. this protein): 5 Avg length: 405,6 Avg pI: 6,89
Protein ID Length (AA) pI
2teHi 512 6,28062
2sKkv 512 7,04959
3Ksw 512 5,97363
A0AAX4G712 247 6,21247
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_35035
7KLgC
 2 36,3% 426 9.569E-88
2 phalp2_14180
2AXSB
 54 33,7% 370 1.284E-51
3 phalp2_17838
8LXT6
 17 26,6% 495 1.065E-50
4 phalp2_30024
2te0R
 2 26,0% 525 9.934E-46
5 phalp2_2869
netU
 143 30,7% 390 1.231E-39
6 phalp2_12996
3nSWw
 2 23,5% 382 1.623E-13

Domains

Domains [InterPro]
Ami3
Unannotated
Unannotated
Representative sequence (used for alignment): 2teHi (512 AA)
Member sequence: A0A3G8F8G9 (245 AA)
1 512 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Phage 5P_2
[NCBI] 		2492474 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK113950 [NCBI]
CDS location
range 7950 -> 8687
strand -
CDS
ATGGCAAAGGTGTGTCTTGATGCTGGCCATGGCGGCTACGATCCTGGAGCCGTTGGGCCAAGTGGTTTGAAGGAAAAAGATGTAACACTTGATGTTGTTTTGAGGGTGGGGAAATATCTCCAGCAAGCGGGTATTGAGGTGGTTTATACCAGAACCAGCGACCAGGTTCTCTGGTCTGCAAGCAAGGACTTGCAGGCACGCTGCGATATTGCCAATCGATCCGGAGCAGACCTTTTTATTTCCGTCCATTGCAATAGCTTTTCTAATCCGCAGGCGGCCGGGACAGAAACATATTCATTGAGTACAACCGGGAATGGTCGAAAAGTGGCAGAATTTATCCAGGCCGAGTTAATTAGCGCGTTGAACCTTACAAATCGGGGACTTAAGACAGCTAACTATTATGTTTTGAAACGCACGTCCATGCCCGCGACTTTAACCGAAGTGGCCTTCATCTCTAACCCGCGGGAAGAGGCCTTGCTACGCGATCCAGCATTCCGGGATAGAGCGGCCCTAGCTATCACGAAAGGCATAGCGAAATATTTTGGAATTGACATACTACCAGCGCCCGTACCACGACCTGGCCCTGCACCAAATGCAGTTAAAATCAGGGTCGGAAACCTAGTGCTTGACGGTTTAATTATCGGCAATATAAGTTATGCGCCGGTCAGAGCGTTAGCTGAAGCGTTGGGGCGGCAGGTTGTATGGAACGAAGCGGAAAAGGCAGTAGATGTGAGATAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2teHi) rather than this protein.
PDB ID
2teHi
Method AlphaFoldv2
Resolution 87.65
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50