Protein

Protein accession
A0A125V9F0 [UniProt]
Representative
3PKQY
Source
UniProt (cluster: phalp2_10781)
Protein name
SH3 type 3 domain-containing protein
Lysin probability
90%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITVIPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITVIPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNENNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRKPSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWIYDNIPDTTTVIIH
Physico‐chemical
properties
protein length:283 AA
molecular weight:32637,6 Da
isoelectric point:7,60
hydropathy:-0,44
Representative Protein Details
Accession
3PKQY
Protein name
3PKQY
Sequence length
187 AA
Molecular weight
20626,23720 Da
Isoelectric point
6,47489
Sequence
VPQDKLCCVFRDSLGTKQHVGWYYNGIAYHAQGHDSGVVKTDNKQYKSWTHYAIMKGLYDSKGNPIEMDKSLIKEEEIIDNKDVIKVLYSAKVTASSGSTVNMRTGPSTSGDIIKKVPIGALVDVVEEAGDWCQIVYDNKTGYMMSKFLVKQEGGEAVTETYYVKIQCASAQEAKRLAELLGQATVG
Other Proteins in cluster: phalp2_10781
Total (incl. this protein): 35 Avg length: 197,4 Avg pI: 8,51
Protein ID Length (AA) pI
3PKQY 187 6,47489
10CSE 215 8,13547
21BPr 187 9,31699
21zOC 187 9,24298
23J0f 153 9,61896
23JE1 187 9,39428
23apV 195 6,83366
23ba6 187 9,41208
23c50 214 9,19830
23rSu 173 9,39280
24LTV 199 9,25355
2qX9W 166 9,36076
3TIaB 369 7,11967
3WNRL 290 7,61514
3ZNZk 217 9,28733
3Zs9R 297 8,24101
3dZ6Y 139 9,73442
3fIMT 193 9,23479
3gjas 209 9,21152
3h8HC 139 9,81281
3o4It 152 5,88553
40maK 204 9,21171
4L3EH 213 9,25349
4SKR1 146 9,63011
4k9og 145 9,50195
4ke7U 192 9,64101
4kfxO 193 9,58215
4khio 225 8,32559
5MduG 151 8,83122
5WF09 151 7,73007
6cuPN 151 6,72896
7DLcN 139 9,62734
7q12x 180 5,04556
8naEh 280 5,38847
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12681
21Enh
 1 32,4% 148 4.713E-18
2 phalp2_10431
23i8B
 1 25,9% 135 1.246E-15
3 phalp2_21031
a3QQ
 2 24,3% 152 1.083E-14
4 phalp2_14251
3dPhf
 9 24,8% 149 3.697E-10
5 phalp2_29538
3tw0p
 2 21,1% 142 2.606E-08
6 phalp2_3087
3ussr
 2 24,6% 154 4.773E-08

Domains

Domains [InterPro]
Unannotated
SH3_3
Representative sequence (used for alignment): 3PKQY (187 AA)
Member sequence: A0A125V9F0 (283 AA)
1 187 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF08239

Taxonomy

  Name Taxonomy ID Lineage
Phage Peptoclostridium phage phiCDIF1296T
[NCBI] 		1677909 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
CP011968 [NCBI]
CDS location
range 3299660 -> 3300511
strand -
CDS
GTGAAATTAACTAAACTAAATATTAAAAAATATAGAGCACCTATATATAAATATGCTTTAGCAAATGTAAATTTGAGGTCTGCTAAATCTACCAATTCAAGTATCATAACAGTAATACCTCAGGGAGCTAAAATGGAAGTATTGGATGAAGAAGATGACTGGATTAAGGTGATGTACAATTCTCAAGAAGGATATGTGTATAAGGATTTGGTATCAGTAAGCGAATATGCTTGGAGTAACTTAAACTTAAGAGAAGATAAATCTACAACTTCCAATATAATTACAGTAATTCCTGAAAAATCTAGGGTTGAAGTCCTTCAAGTAGATGGAGATTGGAGTAAGGTTGTATATGATGATAAAATAGGATATGTTTTTAATTATTTTTTATCAATTGATGGGAATAAACCAAATGAATTAGATTATAAGTATTTTTATACTGACATGATTAAATTTGTTAACGAAAATAATATTAAAAGTACTAGCGATTATCTAATTGTAACAGACCTTAGAAATAAATATACTTATATTTTTAAGAAAGATAATGGAGGCTGGGGACAACTTTACAAGTGGCAATGTACTATAGGTAAGCCTGAGACTCCAACTATAACAGGTATATTTTATATAAGTGGAAGAAAACCTTCTTTTGGAACGGATGAGTATTCAGTTAAATATGCTACTAGAATTAAAGGTGGATATTACTATCATTCTGTGCTATATGATTCAACAGGAAGTTATATAATAGATGGCAGACTTGGTGAAGCTCTTAGTCATGGATGTATAAGATTAAGTACGGAAAATGCAAAGTGGATATATGATAATATACCAGATACAACAACAGTTATAATTCATTAA

Gene Ontology

Description Category Evidence (source)
GO:0008360 regulation of cell shape biological process None (UniProt)
GO:0016740 transferase activity molecular function None (UniProt)
GO:0071555 cell wall organization biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A0A125V9F0
Method AlphaFoldDB
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi00016c6504_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (3PKQY) rather than this protein.
PDB ID
3PKQY
Method AlphaFoldv2
Resolution 79.94
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50