Protein

Protein accession
A0A125V8L0 [UniProt]
Representative
13rsH
Source
UniProt (cluster: phalp2_11559)
Protein name
Phage-related cell wall hydrolase
Lysin probability
96%
PhaLP type
endolysin
Probability: 95% (predicted by ML model)
Protein sequence
MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYADLASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDILDELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILPSITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIYDDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAARLIELIQQYNLQLIDSEIQSEM
Physico‐chemical
properties
protein length:297 AA
molecular weight:34392,0 Da
isoelectric point:9,19
hydropathy:-0,53
Representative Protein Details
Accession
13rsH
Protein name
13rsH
Sequence length
327 AA
Molecular weight
35478,80910 Da
Isoelectric point
9,28920
Sequence
MKKTVAVLMASLMCMGGAAAVASPNVVKPVSAYAITQSQQQQFINNLGTAAQKGYAQYKILPSMTIAQAILESAWGQSTLSSRYYNFFGMKAGSNYHGETVTLQTTEEINGVLVRVNGTFRAYHSFDQGIEGYYQFITGYSRYSNLIGETDYKAACRKIREDGWATDSGYTNKLISLIERYDLTRFDTMVPVTEGYFRACASSYTSIVDALNSIGAESSFAYRKKIAAANNITNYSGTPAQNTTMLNLLKQGRLKKPSSGPSIVYFPACGQSYNSIVDALVSIGADSSYNYRCKIAAANSISGYSGTPAQNTSMLSLLKAGKLIKPN
Other Proteins in cluster: phalp2_11559
Total (incl. this protein): 53 Avg length: 301,5 Avg pI: 6,85
Protein ID Length (AA) pI
13rsH 327 9,28920
13AjU 299 5,74826
1nun2 300 5,55450
2mi3P 313 6,79439
3kPXF 243 8,30309
3r5ng 299 5,74826
3tuI4 259 8,27008
3wgB3 299 5,54666
4VCSI 299 5,54666
5KsbO 299 5,75281
5LW8t 299 5,75918
5PF7o 299 5,74826
5RFbo 299 5,74826
5Sp79 299 5,54666
5VLSO 299 5,74826
5VfNf 338 9,16787
5W0rZ 299 5,74826
5W8uK 338 9,01611
5WGxt 299 5,54660
5WoO6 299 5,74826
5YWh0 338 9,16787
5Z0lM 299 5,67886
60yJP 288 9,08690
61lsK 324 8,68668
632Xg 299 5,54666
647Wo 299 5,54666
64zrL 299 5,74826
6614P 300 5,27838
676SK 300 5,27156
68jtv 299 5,26240
6asWT 300 5,40501
6bOnJ 299 5,54666
6cIGq 288 9,17013
6dipY 338 9,16787
6gaS3 338 9,16787
6hzDB 338 9,09670
6iwys 338 9,16787
6j22M 299 5,54666
6jEaI 299 5,54666
6jOCz 299 5,38773
6pHyD 259 8,27763
6pT0l 338 9,16787
6pWgz 300 5,39006
6tZCY 299 5,54666
6uJRp 288 9,17013
6v0pC 299 5,54666
72BrU 251 9,01605
79g9d 255 8,60990
7rXPu 309 7,60343
8mJhF 299 5,54666
K36f 299 5,54666
NAHb 299 5,54666
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_19230
41fA9
 30 41,6% 228 2.501E-77
2 phalp2_35516
JUJC
 21 32,5% 310 1.213E-45
3 phalp2_21235
1gIfg
 3 36,5% 241 2.081E-40
4 phalp2_28108
7xE0g
 17 36,6% 210 1.776E-31
5 phalp2_20883
6PO0L
 1 30,6% 202 6.016E-31
6 phalp2_21762
3TRfz
 37 24,2% 314 1.360E-26
7 phalp2_1203
8F80g
 19 26,0% 219 6.332E-13

Domains

Domains [InterPro]
Disordered region
GLUCO
Unannotated
Unannotated
Representative sequence (used for alignment): 13rsH (327 AA)
Member sequence: A0A125V8L0 (297 AA)
1 327 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01832

Taxonomy

  Name Taxonomy ID Lineage
Phage Peptoclostridium phage phiCDIF1296T
[NCBI] 		1677909 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
CP011968 [NCBI]
CDS location
range 2385756 -> 2386649
strand -
CDS
ATGAAGAATAAAAAATTCATTGTTATAATACTGATAATATCAATTTTAATAGGTGTATTAGTGAAGGAATATTCATCTAGAGAGATAAAAAAGGATGATATAAATGTCAGTAAGTATATAAAATATGCTGATTTAGCAAGTAAAAATAATGCACAAGTTAACTGGAAGTATGTAGCTTCCATTGTTGCTGTGTTAAATAAAAATAACTTAAAAAACGTTAAGGATTCACAGATACAAGAAGTATCAGATTTATTTGTTAAGAATTTTTCTAAAAATAATAAAATAAATAAGTTAAGTGATATTTTGGATGAGTTAGAATTTAGTAATAGACAAAAAAGATTGGTTGATAATTATATAGACAATCTTAAGGATTATGGTATAAAACCAGAAAGATTGAAGTCTGATACAAAATATATGAAGTTTATTGATGAAATTAAAACAGAAGCAATACAAAATTATAAGGATTATAAAATACTTCCATCTATAACTATTGCACAAGCTATAATAGAATCTAGCTGGGGCAAGTCAACTTTGGCAAAACAATATAACAATCTATTTGGTATAAAGGCTGACGCTTATTGGAAAGGTAAGTCAGTGACTTTAGAAACGAAAGAACATTTAGATACAATTATAGATGATAAATTTAGAATATATGATGATAAAAATGAATCTATAAAAGACCATGCAAAATTTTTAGCCACAAATAAAAGGTATAAAAACAATGGTGTATTTGATGCAAAAACGTATATATATCAAGCTAAAGCATTAGAAAAGGCAGGTTATAGTACTGCGAAGGATGAAAATGGCAATAGTATATATGCAGCTCGTCTAATAGAATTAATTCAACAGTATAATCTTCAATTAATAGACAGTGAAATTCAAAGTGAAATGTAA

Gene Ontology

Description Category Evidence (source)
GO:0004040 amidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A0A125V8L0
Method AlphaFoldDB
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi0000da5432_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (13rsH) rather than this protein.
PDB ID
13rsH
Method AlphaFoldv2
Resolution 82.84
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50