Protein

Protein accession
A0A125V505 [UniProt]
Representative
7xlzz
Source
UniProt (cluster: phalp2_18606)
Protein name
Phage cell wall hydrolase
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MIINRSKDSSSVNINFTAKDMGFLLLQSEVSYNFKDKLVEDIAKQVFADNKLAIGNIPKTNVKYTKMFISVNGYDTIMSAYTEASKTTKKKYMIEANLDKFNIIEKGTVTLNIIFEEGFNLINTTFSESMENVKNKVLLVDQYGNKISEKVNNSLFKEVNVIMQKVIQQQENSTTDIENEFKGIERTCSLKGYGDTSCITGRGVKVKDSYTKLVGLFYIDTDKHTWQNGDYQIELELNFQNIMDEKSVGQDEQKEEISDLSGNGALNGREVKAEFTAYYPSNDPMEGGLYQKMDGKKLVPSNNTCAAPEVLKFKTQIQVKGTGTNIDGKTYTVTDRGGAIKVVNGIYKIDILMSSKKECYNFGRRKGTIIIGDGTGYTNFTGKVKELISIAKGKKGCKYVWGASGPNTFDCSGFTQWCYKKIGINIPRVSRAQGSVGKQVEKKSLQPGDLVFFSSKGPKGTIDHVGILIGNNEFIHSPHTGDVVKISSLKGSYYSKNYVGARRFL
Physico‐chemical
properties
protein length:505 AA
molecular weight:56221,4 Da
isoelectric point:9,06
hydropathy:-0,44
Representative Protein Details
Accession
7xlzz
Protein name
7xlzz
Sequence length
359 AA
Molecular weight
40363,99860 Da
Isoelectric point
5,00231
Sequence
VNFQQIDIPIASTVCFYVDDKELYRGMIINRSKDSSNNSISFVSKDMGFLLTQSEVSYNFKDKLVEDIAKQVFNDNKLAIGNIPKTNVKYTKMFIGVTGYDTIMSAYTEASKTTKKKYMIEANLDKFNVIEKGIVTLNVMFEEGSNLINTSFSESMENVKNKVLVVDQYGNKISEKVNDEIFKDVGIIMQKVIQQQENQTIDIDSEFKGIEQTCNLKGYGDVSCITGRGVKVKDSYTGLTGLFYIDTDKHNWDSNGNYEIDLDLNFQNIMDEKTAGQDEQKEESSDLNGEGTLNGREVKAEFTAYYPSNDPMEGGYYQAMDGKRLVPSNNTCAAPSKLKFKTKIQAKCPGTKIDGKTYT
Other Proteins in cluster: phalp2_18606
Total (incl. this protein): 28 Avg length: 391,1 Avg pI: 6,86
Protein ID Length (AA) pI
7xlzz 359 5,00231
3PSn2 298 6,23299
5ZE1n 471 8,36956
7274h 283 5,32191
79r5t 266 4,83014
79r6b 266 4,71277
7Pxqk 228 7,61599
7RsVC 283 5,32010
7k1LE 288 4,77649
7mq3j 325 5,19442
7mq3k 351 4,93410
7yzMj 334 5,11206
7yzvT 264 4,73755
8JA1e 359 5,02050
8JA2G 283 5,32191
A0A090C9K8 506 8,66927
A0A0A8WF62 506 8,58102
A0A0A8WES0 506 8,67308
Q24LH4 207 9,17284
J9QED2 414 8,18628
A0A090DCQ7 506 8,74902
A0A1V0DZX6 526 6,68872
A0A090D7Z5 515 8,57019
A0A0K2SUC1 515 8,57019
A0A125VBA0 558 7,47685
A0A6B7FQY1 515 8,57019
A0AAE7CTG3 515 8,57019
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27798
7xQBg
 127 67,5% 360 1.337E-171
2 phalp2_2344
4SDRd
 25 33,9% 368 1.889E-67
3 phalp2_22550
1qxeg
 1 30,4% 250 1.037E-34
4 phalp2_10188
xnok
 14 26,2% 248 1.107E-16
5 phalp2_1070
7dkQt
 1 20,0% 265 4.935E-05

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Peptoclostridium phage phiCDIF1296T
[NCBI] 		1677909 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
CP011968 [NCBI]
CDS location
range 1476005 -> 1477522
strand +
CDS
ATGATAATTAACAGATCTAAAGATTCAAGCAGTGTTAATATTAATTTTACAGCCAAGGATATGGGATTTTTACTTTTACAAAGTGAAGTGTCCTATAATTTTAAGGATAAGTTAGTAGAGGATATTGCAAAGCAAGTATTTGCAGATAACAAACTTGCAATTGGAAACATACCAAAGACTAATGTAAAATATACTAAAATGTTTATATCTGTAAACGGATATGATACTATAATGAGTGCTTACACAGAAGCAAGCAAAACTACAAAGAAAAAGTATATGATAGAGGCTAATCTTGATAAATTTAATATTATTGAGAAAGGAACTGTTACATTAAATATCATCTTTGAAGAAGGATTTAATCTTATCAATACGACTTTTTCTGAAAGTATGGAAAATGTAAAGAATAAAGTATTATTAGTTGACCAATATGGAAATAAAATTAGTGAGAAAGTTAATAATTCTTTATTTAAAGAAGTAAATGTGATAATGCAGAAAGTCATACAACAACAGGAAAATAGTACAACAGACATAGAAAACGAGTTTAAAGGAATTGAAAGAACGTGTTCTCTAAAAGGATATGGAGATACAAGTTGTATAACTGGTAGAGGTGTAAAGGTAAAAGATTCGTATACAAAATTGGTAGGATTATTCTATATAGATACAGATAAACATACATGGCAAAATGGAGATTATCAGATTGAATTAGAACTCAATTTTCAAAATATAATGGATGAAAAATCTGTAGGGCAAGATGAACAAAAAGAAGAAATTTCAGATTTAAGTGGTAATGGAGCATTAAATGGAAGAGAAGTAAAAGCAGAATTTACAGCATATTATCCATCAAATGATCCAATGGAAGGTGGCTTATATCAAAAGATGGATGGCAAAAAGCTTGTACCATCTAACAATACTTGTGCTGCTCCTGAAGTGCTTAAGTTTAAAACACAAATACAAGTAAAAGGCACTGGTACAAATATAGATGGAAAAACATATACAGTAACAGATAGGGGAGGAGCTATTAAGGTAGTTAATGGTATTTATAAAATAGATATATTAATGTCTAGTAAAAAAGAATGTTATAATTTTGGAAGAAGAAAAGGTACTATAATTATTGGAGATGGAACAGGATATACAAATTTCACAGGAAAGGTAAAAGAATTAATTAGCATAGCTAAGGGTAAAAAAGGATGTAAATATGTGTGGGGAGCAAGTGGACCAAATACTTTTGATTGCAGTGGGTTTACTCAGTGGTGTTATAAAAAAATAGGAATTAATATTCCTAGAGTATCCAGAGCACAAGGAAGTGTAGGAAAGCAAGTAGAAAAGAAAAGTTTGCAACCAGGAGATTTAGTTTTCTTTTCCTCAAAAGGACCTAAAGGAACTATAGATCATGTTGGTATATTAATTGGGAACAATGAATTTATACATTCTCCACATACTGGTGATGTGGTTAAAATATCTAGTCTAAAAGGAAGCTATTATTCTAAGAATTATGTAGGAGCAAGAAGATTTTTATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A0A125V505
Method AlphaFoldDB
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi00035e46b5_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7xlzz) rather than this protein.
PDB ID
7xlzz
Method AlphaFoldv2
Resolution 88.00
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50